Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Charles A, Marsden"'
Autor:
Si Qin, Mark Epping-Jordan, David A. Kendall, Charles A. Marsden, Ben H.C. Westerink, David E. Ray, Emmanuel Le Poul, Kevin C. F. Fone, Nektaria Papadopoulou, Nisha Kurian, Tyson V. Sharp, Madeleine V. King, Thomas I. F. H. Cremers
Publikováno v:
Neuropsychopharmacology, 39(2), 464-476. Nature Publishing Group
Glutamate is the principle excitatory neurotransmitter in the mammalian brain, and dysregulation of glutamatergic neurotransmission is implicated in the pathophysiology of several psychiatric and neurological diseases. This study utilized novel lenti
Publikováno v:
Neuropharmacology
The cognitive effects of MDMA (‘Ecstasy’) are controversial, particularly in the case of acute administration of low doses. Latent inhibition (LI) refers to the reduction in conditioning to a stimulus that has received non-reinforced pre-exposure
Publikováno v:
Pharmacology Biochemistry and Behavior. 102:357-365
The endocannabinoid signalling system is widely accepted to play a role in controlling the affective state. Plant cannabinoids are well known to have behavioural effects in animals and humans and the cannabinoid CB(1) receptor antagonist rimonabant h
Publikováno v:
Pharmacology Biochemistry and Behavior. 100:506-512
Recent findings indicate that CB1 receptor blockade might be relevant to the action of antidepressant drugs as inhibition of endocannabinoid function can increase synaptic availability of neurotransmitters; an effect also seen with chronic antidepres
Publikováno v:
Psychopharmacology. 221:239-247
Several pre-clinical and human-based studies have shown that acutely administered cannabidiol (CBD) can produce anxiolytic-like effects The present study investigated the effects of chronic administration of CBD on rat behaviour and on the expression
Publikováno v:
Neuropharmacology. 61:400-407
There is increasing awareness of the importance that early environmental factors have on brain development and their role in the neurobiology of neurodevelopmental disorders including schizophrenia. The isolation reared rat attempts to model adverse
Publikováno v:
Advances in Medical Sciences. 56:71-79
Purpose: To examine the effect of dopamine depletion in nucleus accumbens on trace conditioning; to distinguish the role of core and shell sub-regions, as far as possible. Material/Methods: 6-hydroxydopamine was used to lesion dopamine terminals with
Publikováno v:
Behavioral Neuroscience
There is good evidence that the medial prefrontal cortex (mPFC) is involved in different aspects of recognition memory. However, the mPFC is a heterogeneous structure, and the contribution of the prelimbic (PL) and infralimbic (IL) cortices to recogn
Publikováno v:
The International Journal of Neuropsychopharmacology. 15:471-484
Dopamine D3 receptors are densely expressed in mesolimbic projection areas, and selective antagonists enhance cognition, consistent with their potential therapeutic use in the treatment of schizophrenia. This study examines the effect of dopamine D3
Publikováno v:
Phytotherapy Research. 25:858-862
Bergamot essential oil (BEO), Citrus aurantium subsp. bergamia (Risso) Wright & Arn. (Rutaceae), is used widely in aromatherapy to reduce stress and anxiety despite limited scientific evidence. A previous study showed that BEO significantly increased