Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Charles, Ramassamy"'
Autor:
Usma Munawara, Michael Catanzaro, Weili Xu, Crystal Tan, Katsuiku Hirokawa, Nabil Bosco, David Dumoulin, Abdelouahed Khalil, Anis Larbi, Simon Lévesque, Charles Ramassamy, Annelise E. Barron, Stephen Cunnane, Pascale B. Beauregard, Jean-Pierre Bellenger, Serafim Rodrigues, Mathieu Desroches, Jacek M. Witkowski, Benoit Laurent, Eric H. Frost, Tamas Fulop
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-25 (2021)
Abstract Background Alzheimer’s disease (AD) is the most common neurodegenerative disease ultimately manifesting as clinical dementia. Despite considerable effort and ample experimental data, the role of neuroinflammation related to systemic inflam
Externí odkaz:
https://doaj.org/article/6261844794f64438bcf02c6bb6efef09
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 7, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction In brain, extracellular vesicles (EVs) play an essential role in the neuron‐glia interface and ensure the crosstalk between the brain and the periphery. Some studies now link the pathway dysfunction of the EVs to apolipoprotei
Externí odkaz:
https://doaj.org/article/abc7c91dd639474091aef4ae8f46ea99
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction The substantial link between apolipoprotein E (APOE) ε4 allele and oxidative stress may underlie enhanced Alzheimer's disease (AD) risk. Here, we studied the impact of APOE ε4 on the level of apolipoproteins with antioxidant a
Externí odkaz:
https://doaj.org/article/79d6264e6ff34be1b6fdaf05e7c98789
Autor:
Mohamed Haddad, Roger Gaudreault, Gabriel Sasseville, Phuong Trang Nguyen, Hannah Wiebe, Theo Van De Ven, Steve Bourgault, Normand Mousseau, Charles Ramassamy
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2643 (2022)
The overall impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on our society is unprecedented. The identification of small natural ligands that could prevent the entry and/or replication of the coronavirus remains a pertinent app
Externí odkaz:
https://doaj.org/article/4a96c579c9c8446aa53d80630c4d08f6
Autor:
Pierre S. Haddad, Alain Doyen, Krista Coventry, Charles Ramassamy, Guy Rousseau, David H. St-Pierre, Marleny D.A. Saldaña
Publikováno v:
Journal of Natural Health Product Research. 4:1-26
Autor:
Florian Bernard-Patrzynski, Marc-André Lécuyer, Ina Puscas, Imane Boukhatem, Marc Charabati, Lyne Bourbonnière, Charles Ramassamy, Grégoire Leclair, Alexandre Prat, V Gaëlle Roullin
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226302 (2019)
Primary cell isolation from the central nervous system (CNS) has allowed fundamental understanding of blood-brain barrier (BBB) properties. However, poorly described isolation techniques or suboptimal cellular purity has been a weak point of some pub
Externí odkaz:
https://doaj.org/article/5124970efe8d4019966a3720a73640a9
Autor:
Frederik Desmarais, Vincent Hervé, Karl F. Bergeron, Gaétan Ravaut, Morgane Perrotte, Guillaume Fyfe-Desmarais, Eric Rassart, Charles Ramassamy, Catherine Mounier
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4118 (2021)
Apolipoprotein D (ApoD) is a secreted lipocalin associated with neuroprotection and lipid metabolism. In rodent, the bulk of its expression occurs in the central nervous system. Despite this, ApoD has profound effects in peripheral tissues, indicatin
Externí odkaz:
https://doaj.org/article/6666592feaa74dc0b91334e162e2b1c9
Publikováno v:
Foods, Vol 10, Iss 1, p 63 (2020)
Black chokeberry (Aronia melanocarpa) fruits are rich in anthocyanins, which are vital secondary metabolites that possess antioxidative properties. The aim of this study was to isolate and purify the anthocyanins from black chokeberry by simulated mo
Externí odkaz:
https://doaj.org/article/b15cffe6aa8643fda271d2677d687a10
Autor:
Jean-Michel Rabanel, Marziye Mirbagheri, Mateusz Olszewski, Guojun Xie, Marine Le Goas, Pierre-Luc Latreille, Hermine Counil, Vincent Hervé, Rummenigge Oliveira Silva, Charlotte Zaouter, Vahid Adibnia, Mariana Acevedo, Marc J. Servant, Vincent A. Martinez, Shunmoogum A. Patten, Krzysztof Matyjaszewski, Charles Ramassamy, Xavier Banquy
Publikováno v:
ACS nano.
Drug nanocarriers (NCs) capable of crossing the vascular endothelium and deeply penetrating into dense tissues of the CNS could potentially transform the management of neurological diseases. In the present study, we investigated the interaction of bo
Autor:
Charles Ramassamy, Tamas Fulop, Morgane Perrotte, Mohamed Raâfet Ben Khedher, Aurelie Lepage, Elise Madec, Mohamed Haddad
Publikováno v:
Journal of Alzheimer's Disease. 84:227-237
Background: Growing evidence supports that receptor for advanced glycation end products (RAGE) and glyoxalase-1 (GLO-1) are implicated in the pathophysiology of Alzheimer’s disease (AD). Extracellular vesicles (EVs) are nanovesicles secreted by alm