Barriers to implementing antimicrobial stewardship programs in three low- and middle-income country tertiary care settings: findings from a multi-site qualitative study

Autor: Robert Rolfe, Charles Kwobah, Florida Muro, Anushka Ruwanpathirana, Furaha Lyamuya, Champica Bodinayake, Ajith Nagahawatte, Bhagya Piyasiri, Tianchen Sheng, John Bollinger, Chi Zhang, Truls Ostbye, Shamim Ali, Richard Drew, Peter Kussin, Deverick J. Anderson, Christopher W. Woods, Melissa H. Watt, Blandina T. Mmbaga, L. Gayani Tillekeratne

Publikováno v: Antimicrobial Resistance and Infection Control, Vol 10, Iss 1, Pp 1-11 (2021)

Abstract Background Antimicrobial resistance has been named as one of the top ten threats to public health in the world. Hospital-based antimicrobial stewardship programs (ASPs) can help reduce antimicrobial resistance. The purpose of this study was

Externí odkaz: https://doaj.org/article/61e2f5e9cce04fc3b6e1a886e93f165a

Point-prevalence survey of antibiotic use at three public referral hospitals in Kenya.

Autor: Sylvia Omulo, Margaret Oluka, Loice Achieng, Eric Osoro, Rosaline Kinuthia, Anastasia Guantai, Sylvia Adisa Opanga, Marion Ongayo, Linus Ndegwa, Jennifer R Verani, Eveline Wesangula, Jarred Nyakiba, Jones Makori, Wilson Sugut, Charles Kwobah, Hanako Osuka, M Kariuki Njenga, Douglas R Call, Guy H Palmer, Daniel VanderEnde, Ulzii-Orshikh Luvsansharav

Publikováno v: PLoS ONE, Vol 17, Iss 6, p e0270048 (2022)

Antimicrobial stewardship encourages appropriate antibiotic use, the specific activities of which will vary by institutional context. We investigated regional variation in antibiotic use by surveying three regional public hospitals in Kenya. Hospital

Externí odkaz: https://doaj.org/article/379ed76c1c1342e1a996f444599667de

Sickle Cell Disease and HIV

Autor: Esther Brenda Odera MBChB, Charles Kwobah MBChB, Geren Stone MD, Faraj Some MBChB, MMED, Rachel Christine Vreeman MD, MS

Publikováno v: Journal of the International Association of Providers of AIDS Care, Vol 13 (2014)

Sickle cell disease (SCD) is a genetic disorder resulting from a mutation in the hemoglobin (Hb) gene. Sickle cell disease results in chronic anemia and a variety of acute and chronic complications that can lead to early mortality. A child with both

Externí odkaz: https://doaj.org/article/737e1080cad84e5fb288077615ccc399

Neurocognitive function at the first-line failure and on the second-line antiretroviral therapy in Africa: Analyses from the EARNEST trial

Autor: Earnest Trial Team, Nicholas I. Paton, Jennifer Thompson, Alejandro Arenas-Pinto, James Hakim, Andrew Kambugu, Charles Kwobah, Sarah Walker, Raymond Mwebaze, D. Tumukunde, Anne Hoppe, Joep J. van Oosterhout, James Abach

OBJECTIVE: To assess neurocognitive function at the first-line antiretroviral therapy failure and change on the second-line therapy. DESIGN: Randomized controlled trial was conducted in 5 sub-Saharan African countries. METHODS: Patients failing the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc486dbfa7a505f63ef84ab3c4ee6416
https://doi.org/10.1097/qai.0000000000000898

Point-prevalence survey of antibiotic use at three public referral hospitals in Kenya.

Autor: Omulo, Sylvia^1,2,3 (AUTHOR) sylvia.omulo@wsu.edu, Oluka, Margaret⁴ (AUTHOR), Achieng, Loice⁵ (AUTHOR), Osoro, Eric^1,2 (AUTHOR), Kinuthia, Rosaline⁶ (AUTHOR), Guantai, Anastasia⁴ (AUTHOR), Opanga, Sylvia Adisa⁷ (AUTHOR), Ongayo, Marion⁸ (AUTHOR), Ndegwa, Linus⁹ (AUTHOR), Verani, Jennifer R.⁹ (AUTHOR), Wesangula, Eveline¹⁰ (AUTHOR), Nyakiba, Jarred¹⁰ (AUTHOR), Makori, Jones¹¹ (AUTHOR), Sugut, Wilson¹² (AUTHOR), Kwobah, Charles^12,13 (AUTHOR), Osuka, Hanako¹⁴ (AUTHOR), Njenga, M. Kariuki^1,2 (AUTHOR), Call, Douglas R.¹ (AUTHOR), Palmer, Guy H.^1,2 (AUTHOR), VanderEnde, Daniel¹⁴ (AUTHOR)

Publikováno v: PLoS ONE. 6/16/2022, Vol. 17 Issue 6, p1-11. 11p.