Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Charles, Glaus"'
Autor:
Nancy Chen, David E. Ehmann, Robert Crooker, Katayoun Derakhchan, Xiaodong Fang, Brian Felice, Elizabeth J. Galbreath, Charles Glaus, Hongbo Gu, Yan Huang, Christine Li, Xing Li, Nan Liu, Kathleen Palmieri, Damir Simic, Joseph Sypek, Susan Thompson, Christopher T. Winkelmann, Vivian W. Choi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 286-302 (2023)
Mucopolysaccharidosis II (MPS II) is a rare lysosomal storage disease characterized by deficient activity of iduronate-2-sulfatase (I2S), leading to pathological accumulation of glycosaminoglycans (GAGs) in tissues. We used iduronate-2-sulfatase knoc
Externí odkaz:
https://doaj.org/article/b33a6cf79e06450e92ea9144dc1312b7
Autor:
Vincent A. Stadelmann, Gabrielle Boyd, Martin Guillot, Jean-Guy Bienvenu, Charles Glaus, Aurore Varela
Publikováno v:
International Journal of Biomedical Imaging, Vol 2021 (2021)
Objective. While microCT evaluation of atherosclerotic lesions in mice has been formally validated, existing image processing methods remain undisclosed. We aimed to develop and validate a reproducible image processing workflow based on phosphotungst
Externí odkaz:
https://doaj.org/article/de3c6ee816b44f3bbfc576a3d40cfb50
Autor:
Pedro J. Beltran, Courtney Beers, Rafael Ponce, Andrea M. Boden, David H. Cordover, Kenneth Ganley, Charles Glaus, Kim Merriam, Oluwatayo F. Ikotun, Brian Belmontes, Tiep Le, Becky Yang, Jinghui Zhan, Karen Fitzgerald, James B. Rottman, Petia Mitchell, Julia Piasecki, Keegan Cooke, Achim K. Moesta
Supp Figures S1 to S6 and Supp Tables S1 to S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503f6582b7cb25df46e86a0d409ba0b5
https://doi.org/10.1158/1078-0432.22463246
https://doi.org/10.1158/1078-0432.22463246
Autor:
Pedro J. Beltran, Courtney Beers, Rafael Ponce, Andrea M. Boden, David H. Cordover, Kenneth Ganley, Charles Glaus, Kim Merriam, Oluwatayo F. Ikotun, Brian Belmontes, Tiep Le, Becky Yang, Jinghui Zhan, Karen Fitzgerald, James B. Rottman, Petia Mitchell, Julia Piasecki, Keegan Cooke, Achim K. Moesta
Purpose: Talimogene laherparepvec, a new oncolytic immunotherapy, has been recently approved for the treatment of melanoma. Using a murine version of the virus, we characterized local and systemic antitumor immune responses driving efficacy in murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290bbe6502f2d8ee72ab096276248d16
https://doi.org/10.1158/1078-0432.c.6525350.v1
https://doi.org/10.1158/1078-0432.c.6525350.v1
Autor:
Brad Herberich, Thomas Nixey, Lin Yin, Tayo Ikotun, Kelvin K. C. Sham, Jason Long, Hongyan Li, Charles Glaus, Xuhai Be, Les P. Miranda, Yuan Cheng, Marcus Soto, James R. Falsey, Bryan D. Moyer, Robert S. Foti, Christopher M. Tegley, Chawita Netirojjanakul, Linh Tran, Kip P. Conner, Jennifer Aral, Liyue Huang, Kaustav Biswas, Justin K. Murray, Bin Wu, Loren Berry, Dean Hickman, Dan A. Rock
Publikováno v:
Drug Metabolism and Disposition. 47:1111-1121
The identification of nonopioid alternatives to treat chronic pain has received a great deal of interest in recent years. Recently, the engineering of a series of Nav1.7 inhibitory peptide-antibody conjugates has been reported, and herein, the precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aafa704103c2cd45fe6f198cffc5d5f
https://doi.org/10.1124/dmd.119.087742
https://doi.org/10.1124/dmd.119.087742
Autor:
Bryan D. Moyer, Brad Herberich, Kaustav Biswas, Kenneth W. Walker, Beth D. Youngblood, Jennifer Aral, Tayo Ikotun, Min-Hwa Jasmine Lin, Linh Tran, Thomas Kornecook, Hongyan Li, Thomas Nixey, Joseph Ligutti, Shanti Amagasu, Li Yin, Xuhai Be, Kristin L. Andrews, Christopher M. Tegley, Charles Glaus, Marcus Soto, Les P. Miranda, James R. Falsey, Jason Long, Yuan Cheng, Robert S. Foti, Hossein Salimi-Moosavi, Kelvin Sham, Christopher P Ilch, Bin Wu, Justin K. Murray, Margaret Karow, Chawita Netirojjanakul, Liz Doherty
Publikováno v:
ACS Chemical Biology. 14:806-818
Drug discovery research on new pain targets with human genetic validation, including the voltage-gated sodium channel NaV1.7, is being pursued to address the unmet medical need with respect to chronic pain and the rising opioid epidemic. As part of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68d1aa4016111a37796e962e98dcd944
https://doi.org/10.1021/acschembio.9b00183
https://doi.org/10.1021/acschembio.9b00183
Autor:
Qiang Zhang, Eun Chul Cho, Younan Xia, Lihong V. Wang, Michael J. Welch, Miaoxin Yang, Charles Glaus, Jingyi Chen, Claire M. Cobley, Chulhong Kim
Publikováno v:
Adv Funct Mater
Gold nanocages represent a novel class of nanostructures, well-suited for biomedical applications. They can be readily prepared via the galvanic replacement reaction between silver nanocubes and chloroauric acid. Their optical resonance peaks can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac3dd682f9188271735484a2fdc4822
https://pubmed.ncbi.nlm.nih.gov/33907543
https://pubmed.ncbi.nlm.nih.gov/33907543
Autor:
Charles Glaus, Luc Bracoud, Chris J Conklin, John D. Port, Leslie Jacobsen, Joyce Suhy, David Scott
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59f6cde666a0e683fb1f9a55a7578fdf
https://doi.org/10.1002/alz.039016
https://doi.org/10.1002/alz.039016
Autor:
Alison Wolfreys, Marina Stolina, Aimee M. Deaton, Sheetal V. Kumar, Jun Yin, Gabrielle Boyd, James R. Turk, Charles Glaus, Emily M. de Koning, Lucas D. Ward, Aurore Varela, Yusheng Qu, Gill Holdsworth, Jean-Guy Bienvenu, Yudong D. He, Martin Guillot, Melanie Felx, Denise Dwyer, Michael J. Engwall, Rogely W. Boyce, Kathrin Locher
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 115
Romosozumab (EVENITY™ [romosozumab-aqqg in the US]) is a humanized monoclonal antibody that inhibits sclerostin and has been approved in several countries for the treatment of osteoporosis in postmenopausal women at high risk of fracture. Sclerosti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869719aab28883f3928edc99a9d7aba0
https://pubmed.ncbi.nlm.nih.gov/32590049
https://pubmed.ncbi.nlm.nih.gov/32590049
Autor:
Andrea Boden, James B. Rottman, David Cordover, Tiep Le, Oluwatayo Ikotun, Kenneth Ganley, Julia C. Piasecki, Rafael Ponce, Brian Belmontes, Karen Fitzgerald, Jinghui Zhan, Charles Glaus, Kim Merriam, Achim K. Moesta, Courtney Beers, Pedro J. Beltran, Keegan Cooke, Petia Mitchell, Becky Yang
Publikováno v:
Clinical Cancer Research. 23:6190-6202
Purpose: Talimogene laherparepvec, a new oncolytic immunotherapy, has been recently approved for the treatment of melanoma. Using a murine version of the virus, we characterized local and systemic antitumor immune responses driving efficacy in murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa52854c59f28d894047f27b92c5c1e
https://doi.org/10.1158/1078-0432.ccr-17-0681
https://doi.org/10.1158/1078-0432.ccr-17-0681