Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Charles, Dinarello"'
Autor:
Eunjeong Lee, Jasmina S. Redzic, Travis Nemkov, Anthony J. Saviola, Monika Dzieciatkowska, Kirk C. Hansen, Angelo D’Alessandro, Charles Dinarello, Elan Z. Eisenmesser
Publikováno v:
Molecules, Vol 27, Iss 14, p 4494 (2022)
Toll-interleukin receptor (TIR) domains have emerged as critical players involved in innate immune signaling in humans but are also expressed as potential virulence factors within multiple pathogenic bacteria. However, there has been a shortage of st
Externí odkaz:
https://doaj.org/article/d24b68bd4a8d449685f8cbbcd76342ea
Autor:
Christel Rothe Brinkmann, Jesper Falkesgaard Højen, Thomas Aagaard Rasmussen, Anne Sofie Kjær, Rikke Olesen, Paul W. Denton, Lars Østergaard, Zhengyu Ouyang, Mathias Lichterfeld, Xu Yu, Ole Schmeltz Søgaard, Charles Dinarello, Martin Tolstrup
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT Histone deacetylase inhibitors (HDACi) modulate the transcriptional activity of all cells, including innate and adaptive immune cells. Therefore, we aimed to evaluate immunological effects of treatment with the HDACi panobinostat in HIV-infe
Externí odkaz:
https://doaj.org/article/42a41f93e9564a62ab717ed0df2a75eb
Autor:
Shi Biao Chia, Catherine Pham-Danis, Hannah Scarborough, Nathaniel Little, Etienne P. Danis, Andrew E. Goodspeed, Charles Dinarello, James DeGregori
Publikováno v:
Cancer Research. 82:A026-A026
Aging is a major risk factor in increased lung cancer incidence. While most research has focused on age-associated mutation accumulation to explain the late-life increase in cancer incidence, there are tissue environmental forces that both impede and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35f092da13bbff9bc171c92a22a5f640
https://doi.org/10.1158/1538-7445.evodyn22-a026
https://doi.org/10.1158/1538-7445.evodyn22-a026
Autor:
Wolfgang Schleicher, James Chavez, Rachel Culp-Hill, Angelo D'Alessandro, charles Dinarello, Rachel Gessner, Gang Huang, Zhonghe Ke, Taylor Mills, Eric Pietras, Isak Tengesdal, Jennifer Trowbridge
Publikováno v:
Experimental Hematology. 111:S136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70dcd75673ce0367f0755382d5d6878f
https://doi.org/10.1016/j.exphem.2022.07.239
https://doi.org/10.1016/j.exphem.2022.07.239
THU0010 THE ANTI-INFLAMMATORY CYTOKINE INTERLEUKIN 37 IS AN ENDOGENOUS INHIBITOR OF TRAINED IMMUNITY
Autor:
Giulio Cavalli, Mark Gresnict, Rob Arts, Travis Nemkov, Angelo D’alessandro, Silvia Giugliano, Elan Eisenmesser, Lorenzo Dagna, Leo Joosten, Mihai Netea, Charles Dinarello
Publikováno v:
Poster Presentations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::430f117d32c953f4ad682bc0c3525ae1
https://doi.org/10.1136/annrheumdis-2019-eular.3008
https://doi.org/10.1136/annrheumdis-2019-eular.3008
Autor:
Christel Rothe, Brinkmann, Jesper Falkesgaard, Højen, Thomas Aagaard, Rasmussen, Anne Sofie, Kjær, Rikke, Olesen, Paul W, Denton, Lars, Østergaard, Zhengyu, Ouyang, Mathias, Lichterfeld, Xu, Yu, Ole Schmeltz, Søgaard, Charles, Dinarello, Martin, Tolstrup
Publikováno v:
mSphere
The effect of treatment with histone deacetylase inhibitors on the immune system in HIV-infected individuals is not clear. Analysis of results from a clinical trial in which 15 HIV-infected individuals received 12 doses of panobinostat identified a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09e95ccfacf73e16544d540d735c53dc
https://pubmed.ncbi.nlm.nih.gov/29468194
https://pubmed.ncbi.nlm.nih.gov/29468194
Publikováno v:
The Journal of Immunology. 192:69.4-69.4
To perform their expected functions, immune molecules must be targeted to specific cellular compartments such as the plasma membrane. Improper protein targeting can lead to major forms of immune disease such as immunodeficiency and persistent inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::948de8ce4452e0a3a41c1ad69d183627
https://doi.org/10.4049/jimmunol.192.supp.69.4
https://doi.org/10.4049/jimmunol.192.supp.69.4
Autor:
Claudia Nold, Marcel Nold, Ina Rudloff, Camden Lo, Niamh Mangan, Bjoern Rotter, Jarod Zepp, Tania Azam, Suzhao Li, Ashley Mansell, Philip Bufler, Cecilia Garlanda, Alberto Mantovani, Charles Dinarello
Publikováno v:
The Journal of Immunology. 190:184.7-184.7
IL-37 is a powerful anti-inflammatory IL-1 family member with activity against a broad spectrum of inflammatory assaults. One mechanism by which this beneficial effect is mediated is via intracellular association with Smad3; however, the cell surface
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e33b769dc078f5eaa101b5811517bc7
https://doi.org/10.4049/jimmunol.190.supp.184.7
https://doi.org/10.4049/jimmunol.190.supp.184.7