Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Charles, Annicelli"'
Autor:
Jaechul Lim, Erica V. Lin, Jun Young Hong, Bharat Vaidyanathan, Steven A. Erickson, Charles Annicelli, Ruslan Medzhitov
Publikováno v:
Journal of Experimental Medicine. 219
IgE mediates allergic responses by coating mast cell or basophil surfaces and inducing degranulation upon binding a specific allergen. IgE can also be spontaneously produced in the absence of foreign allergens; yet the origin, regulation, and functio
Autor:
Karen, Agaronyan, Lokesh, Sharma, Bharat, Vaidyanathan, Keith, Glenn, Shuang, Yu, Charles, Annicelli, Talia D, Wiggen, Mitchell R, Penningroth, Ryan C, Hunter, Charles S, Dela Cruz, Ruslan, Medzhitov
Publikováno v:
Immunity. 55:895-911.e10
Different effector arms of the immune system are optimized to protect from different classes of pathogens. In some cases, pathogens manipulate the host immune system to promote the wrong type of effector response-a phenomenon known as immune deviatio
Autor:
Maya E Kotas, Hui-Young Lee, Matthew P Gillum, Charles Annicelli, Blas A Guigni, Gerald I Shulman, Ruslan Medzhitov
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25478 (2011)
Invariant natural killer T cells (iNKTs) are innate-like T cells that are highly concentrated in the liver and recognize lipids presented on the MHC-like molecule CD1d. Although capable of a myriad of responses, few essential functions have been desc
Externí odkaz:
https://doaj.org/article/5305b80ee5884dca8f59a7912f37b10e
Autor:
Jun Young Hong, Fernando Carvalho, Jaechul Lim, Ruslan Medzhitov, W. K. Eddie Ip, Charles Annicelli, Jen Young Cho, Bharat Vaidyanathan, Shuang Yu
Publikováno v:
Cell. 180:847-861.e15
Early life environmental exposure, particularly during perinatal period, can have a life-long impact on organismal development and physiology. The biological rationale for this phenomenon is to promote physiological adaptations to the anticipated env
Autor:
Charles Annicelli, Michael J. Jurczak, Maya E. Kotas, Ruslan Medzhitov, Matthew P. Gillum, Gary W. Cline, Gerald I. Shulman
Publikováno v:
Proceedings of the National Academy of Sciences. 110:4810-4815
Caspase-1 is a cysteine protease that can be activated by both endogenous and exogenous inflammatory stimuli and has been shown to have important functions in processes as diverse as proteolytic activation of cytokines, cell death, and membrane repai
Publikováno v:
Cell Host & Microbe. 7(2):103-114
SummaryMulticellular organisms are continuously exposed to many different pathogens. Because different classes of pathogens require different types of immune responses, understanding how an ongoing immune response to one type of infection affects the
Autor:
Ruslan Medzhitov, Charles Annicelli, Hui-Young Lee, Blas A. Guigni, Maya E. Kotas, Gerald I. Shulman, Matthew P. Gillum
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25478 (2011)
PLoS ONE
PLoS ONE
Invariant natural killer T cells (iNKTs) are innate-like T cells that are highly concentrated in the liver and recognize lipids presented on the MHC-like molecule CD1d. Although capable of a myriad of responses, few essential functions have been desc