Zobrazeno 1 - 4
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pro vyhledávání: '"Charlene Watterston"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009769 (2021)
Vessel growth integrates diverse extrinsic signals with intrinsic signaling cascades to coordinate cell migration and sprouting morphogenesis. The pro-angiogenic effects of Vascular Endothelial Growth Factor (VEGF) are carefully controlled during spr
Externí odkaz:
https://doaj.org/article/cd02e6b0683e443196d0ddc66ed48532
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008163 (2019)
As small regulatory transcripts, microRNAs (miRs) act as genetic 'fine tuners' of posttranscriptional events, and as genetic switches to promote phenotypic switching. The miR miR26a targets the BMP signalling effector, smad1. We show that loss of miR
Externí odkaz:
https://doaj.org/article/15c7cec7987b43b4ab5831bf2a8576a4
Autor:
Sarah J. Childs, Carrie L. Hehr, Charlene Watterston, Rami Halabi, Risa Mori-Kreiner, Sarah McFarlane
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Pathological blood vessel growth in the eye is implicated in several diseases that result in vision loss, including age-related macular degeneration and diabetic retinopathy. The limits of current disease therapies have created the need to id
Vascular smooth muscle cells (vSMC) are essential to the integrity of blood vessels, and therefore an attractive target of therapeutics aimed at improving vascular function. Smooth muscle cells are one of the few cell types that maintain plasticity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ec9a623bb6cbcee94dacbc1a073905