Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Charlene M. Vikse"'
Publikováno v:
Radiotherapy and Oncology. 51:179-185
Hypoxic cells are present in some solid tumours and are known to limit radiocurability. To compare two measures of tumour hypoxia, 25 patients with locally advanced disease and accessible tumours or metastatic nodes were examined using an oxygen micr
Publikováno v:
Radiotherapy and Oncology. 50:113-119
Background and purpose : Approximately 18% of the cells recovered by rapid mechanical dissociation of SiHa xenograft tumours contain large numbers of DNA strand breaks. The number of damaged cells increases to 30–40% 4–6 h after exposure to 5 or
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 29:487-491
Purpose: To apply the alkaline comet assay to the detection of radiobiologically hypoxic cells in solid tumors and normal tissues of mice, and to examine the influence of strand break repair on the oxygen enhancement ratio measured using the alkaline
Publikováno v:
International journal of radiation oncology, biology, physics. 22(3)
Oxygen diffusion distance was measured in solid tumor “cubes” prepared by excising the tumor from the mouse and incubating 1–2 mm sided tumor cubes in spinner culture flasks with fluorescent drugs (AF-2 or DM113) which bind to hypoxic cells. Af