Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Charlene M. Mello"'
Publikováno v:
Langmuir. 36:12383-12393
Lipopolysaccharide (LPS) is a component of the outer membrane of Gram-negative bacteria. Recently, a label-free immobilized antimicrobial peptide (AMP) surface plasmon resonance platform was developed to successfully distinguish LPS from multiple bac
Publikováno v:
The Analyst. 144:7242-7249
Rapid detection and identification of bacteria is important for human health, biodefense, and food safety. Small arrays of different antimicrobial peptides (AMPs) enable the identification of lipopolysaccharide (LPS) samples from a variety of bacteri
Publikováno v:
ACS Biomaterials Science & Engineering. 2:1894-1904
The immobilization of antimicrobial peptides (AMPs) to surfaces, enabling their utilization in biosensor and antibacterial/antifouling coating applications, is typically performed using rigid, solid support materials such as glass or gold and may req
Publikováno v:
Applied Biochemistry and Biotechnology. 180:10-25
Botulinum neurotoxin (BoNT), a category A agent, is the most toxic molecule known to mankind. The endopeptidase activity of light chain domain of BoNT is the cause for the inhibition of the neurotransmitter release and the flaccid paralysis that lead
Publikováno v:
Chemical Physics Letters. 619:247-255
Surface immobilized peptides/proteins have important applications such as antimicrobial coating and biosensing. We report a study of such peptides/proteins using sum frequency generation vibrational spectroscopy and ATR-FTIR. Immobilization on surfac
Autor:
Xiaofeng Han, Yuwei Liu, Fu-Gen Wu, Joshua Jansensky, Taehoon Kim, Zhan Chen, Zunliang Wang, Charles L. Brooks, Jianfeng Wu, Chuanwu Xi, Charlene M. Mello
Publikováno v:
The Journal of Physical Chemistry B. 118:2904-2912
Molecular structures such as conformation and orientation are crucial in determining the activity of peptides immobilized to solid supports. In this study, sum frequency generation (SFG) vibrational spectroscopy was applied to investigate such struct
Publikováno v:
Langmuir. 29:11705-11712
Sum frequency generation (SFG) vibrational spectroscopy and attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) were used to investigate the orientation of N-terminus cysteine-modified cecropin P1 (cCP1) at the polystyrene
Autor:
Nina C. Shapley, Anubhav Tripathi, Paul Calvert, Kristin Gilida, Kenneth Morabito, Da Peng Li, Charlene M. Mello
Publikováno v:
Advanced Materials Research. 441:192-199
Natural dyes are normally unstable to photooxidation by UV light. We have measured the stability of a number of natural dyes in combination with high concentrations of antioxidants, excited state quenchers, and UV absorbers. We find that certain comb
Publikováno v:
The Journal of Physical Chemistry B. 115:15228-15235
Antimicrobial peptides (AMPs) are naturally occurring polymers that can kill bacteria by destabilizing their membranes. A quartz crystal microbalance with dissipation monitoring (QCM-D) was used to better understand the action of the AMP chrysophsin-
Autor:
Michael Blank, Michael Blind, Tzuu-Wang Chang, Shuowei Cai, Bal Ram Singh, Pavithra Janardhanan, Charlene M. Mello
Publikováno v:
Biochemical and Biophysical Research Communications. 396:854-860
The category A agent, botulinum neurotoxin (BoNT), is the most toxic molecule known to mankind. The endopeptidase activity of light chain domain of BoNT is the cause for the inhibition of the neurotransmitter release and the flaccid paralysis that le