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pro vyhledávání: '"Charlene M. Dawidczyk"'
Figure S1. Comparison of the dose of different nanomedicines from pre-clinical trials reported in a recent meta-study. Figure S2. Variations in tumor accumulation from 5 pre-clinical trials of nanomedicines in colon adenocarcinoma xenografts (C26).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c333cee1e40aebce22495380d298e8
https://doi.org/10.1158/0008-5472.22406024
https://doi.org/10.1158/0008-5472.22406024
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 13:1637-1644
Systemic drug delivery to a solid tumor involves a sequence of steps that determine efficacy and survival. Extravasation from circulation at the tumor site is a critical step in this sequence since it regulates how much of the drug accumulates in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1344687933b6490e63ee4603de4f37c
https://doi.org/10.1016/j.nano.2017.02.008
https://doi.org/10.1016/j.nano.2017.02.008
Autor:
Cindi L. Dennis, Julie A. Borchers, Martin G. Pomper, Lauren E. Woodard, Charlene M. Dawidczyk, Peter C. Searson, Esteban Velarde, Robert Ivkov, Anilchandra Attaluri
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Magnetic iron oxide nanoparticles (MIONs) have established a niche as a nanomedicine platform for diagnosis and therapy, but they present a challenging surface for ligand functionalization which limits their applications. On the other hand, coating M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776c1e2a3b8b1e54b1f33aa76f749a82
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1530
Quantitative evaluation of nanoparticle delivery to a tumor site can be invaluable for cross-platform comparison, a consideration not currently taken into account by many in the field of cancer nanomedicine (Dawidczyk et al., Front Chem 2:69, 2014).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2562580e68adda8fb96349994a962f6e
https://pubmed.ncbi.nlm.nih.gov/28150206
https://pubmed.ncbi.nlm.nih.gov/28150206
Publikováno v:
Methods in Molecular Biology ISBN: 9781493966448
Quantitative evaluation of nanoparticle delivery to a tumor site can be invaluable for cross-platform comparison, a consideration not currently taken into account by many in the field of cancer nanomedicine (Dawidczyk et al., Front Chem 2:69, 2014).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d2d485f51bbe7db9388e4a08eab2fe3
https://doi.org/10.1007/978-1-4939-6646-2_14
https://doi.org/10.1007/978-1-4939-6646-2_14
Publikováno v:
Cancer research. 75(19)
Nanoparticle-based delivery systems provide new opportunities to overcome the limitations associated with traditional small-molecule drug therapy for cancer and to achieve both therapeutic and diagnostic functions in the same platform. Preclinical tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104ca41784a83adc58b14084cd47928f
https://pubmed.ncbi.nlm.nih.gov/26249177
https://pubmed.ncbi.nlm.nih.gov/26249177
Publikováno v:
Frontiers in Chemistry, Vol 2 (2014)
Frontiers in Chemistry
Frontiers in Chemistry
The ability to efficiently deliver a drug or gene to a tumor site is dependent on a wide range of factors including circulation time, interactions with the mononuclear phagocyte system, extravasation from circulation at the tumor site, targeting stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410886590b4ac7e5e9ba5c41cdcbd387
Autor:
Martin G. Pomper, Luisa M. Russell, Peter C. Searson, Kwan Hyi Lee, Chloe Kim, Charlene M. Dawidczyk, Jeaho Park
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 187
The ability to efficiently deliver a drug to a tumor site is dependent on a wide range of physiologically imposed design constraints. Nanotechnology provides the possibility of creating delivery vehicles where these design constraints can be decouple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69028800a8bba5a959f2bdc4d96224a
https://pubmed.ncbi.nlm.nih.gov/24874289
https://pubmed.ncbi.nlm.nih.gov/24874289