Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Charlene E Kan"'
Supplementary Figure 4 from p53-Mediated Growth Suppression in Response to Nutlin-3 in Cyclin D1–Transformed Cells Occurs Independently of p21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d6a7f5ba2ba1358d118deb6a0ba4b1
https://doi.org/10.1158/0008-5472.22368212.v1
https://doi.org/10.1158/0008-5472.22368212.v1
Interaction of cyclin D1 with cyclin-dependent kinases (CDK) results in the hyperphosphorylation of the RB family of proteins, thereby inactivating the tumor-suppressive function of RB. Our previous findings suggest that constitutive cyclin D1/CDK ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26084b32202f247d77905b9065e459bc
https://doi.org/10.1158/0008-5472.c.6495854.v1
https://doi.org/10.1158/0008-5472.c.6495854.v1
Supplementary Figure Legends 1-4 from p53-Mediated Growth Suppression in Response to Nutlin-3 in Cyclin D1–Transformed Cells Occurs Independently of p21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d6ddf5b2e70148ae4adb69ff72f686
https://doi.org/10.1158/0008-5472.22368209
https://doi.org/10.1158/0008-5472.22368209
Supplementary Figure 3 from p53-Mediated Growth Suppression in Response to Nutlin-3 in Cyclin D1–Transformed Cells Occurs Independently of p21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1a02350a03204f6846f9960d472e9e
https://doi.org/10.1158/0008-5472.22368215
https://doi.org/10.1158/0008-5472.22368215
Autor:
Charlene E Kan, David B. Mansur
The local treatment of cutaneous melanoma with surgical excision is well-established; however, the role of adjuvant radiation is not well-defined. Characteristics of the primary melanoma can indicate a higher local recurrence risk and thus warrant co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084133c70ba111e8543a6b2daab4dd18
https://europepmc.org/articles/PMC6094658/
https://europepmc.org/articles/PMC6094658/
Autor:
Martha R. Stampfer, Charlene E. Kan, Mark W. Jackson, James Graham, David Danielpour, Rocky Cipriano
Publikováno v:
Proceedings of the National Academy of Sciences. 108:8668-8673
Oncogene-induced senescence (OIS), the proliferative arrest engaged in response to persistent oncogene activation, serves as an important tumor-suppressive barrier. We show here that finite lifespan human mammary epithelial cells (HMEC) undergo a p16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5817085067132b5eff821f9c9bf376
https://doi.org/10.1073/pnas.1015022108
https://doi.org/10.1073/pnas.1015022108
Autor:
Christopher C. Barney, Douglas A Murrey, Maria A. Burnatowska-Hledin, Ping Zhao, Jennifer B Kossoris, Charlene E Kan, Jessica L Abbott, Christa J. Van Dort, Rebecca L Shearer
Publikováno v:
Biochemical and Biophysical Research Communications. 319:817-825
Vasopressin-activated calcium-mobilizing (VACM-1), a cul-5 gene, is localized on chromosome 11q22-23 close to the gene for Ataxia Telangiectasia in a region associated with a loss of heterozygosity in breast cancer tumor samples. To examine the biolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c26dd1462ab05fafe1b667f88d8e88
https://doi.org/10.1016/j.bbrc.2004.05.057
https://doi.org/10.1016/j.bbrc.2004.05.057
Publikováno v:
Cancer research. 71(22)
Cytokines play an important role in creating an inflammatory microenvironment, which is now considered a hallmark of cancer. Although tumor cells can exploit cytokine signaling to promote growth, invasion, and metastasis, the response of normal and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bb593690a6606074157a5a867f75a9
https://pubmed.ncbi.nlm.nih.gov/21975934
https://pubmed.ncbi.nlm.nih.gov/21975934
Publikováno v:
Cancer research. 67(20)
Interaction of cyclin D1 with cyclin-dependent kinases (CDK) results in the hyperphosphorylation of the RB family of proteins, thereby inactivating the tumor-suppressive function of RB. Our previous findings suggest that constitutive cyclin D1/CDK ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208b2192c9c1db4f7f89ed786fb50de4
https://pubmed.ncbi.nlm.nih.gov/17942917
https://pubmed.ncbi.nlm.nih.gov/17942917