Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Charlene Babra Waryah"'
Autor:
Colette Moses, Fiona Nugent, Charlene Babra Waryah, Benjamin Garcia-Bloj, Alan R. Harvey, Pilar Blancafort
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 287-300 (2019)
PTEN expression is lost in many cancers, and even small changes in PTEN activity affect susceptibility and prognosis in a range of highly aggressive malignancies, such as melanoma and triple-negative breast cancer (TNBC). Loss of PTEN expression occu
Externí odkaz:
https://doaj.org/article/503bcc715184465fa441c4798c38d35c
Autor:
Jully Gogoi-Tiwari, Vincent Williams, Charlene Babra Waryah, Paul Costantino, Hani Al-Salami, Sangeetha Mathavan, Kelsi Wells, Harish Kumar Tiwari, Nagendra Hegde, Shrikrishna Isloor, Hesham Al-Sallami, Trilochan Mukkur
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170668 (2017)
BACKGROUND:Biofilm formation by Staphylococcus aureus is an important virulence attribute because of its potential to induce persistent antibiotic resistance, retard phagocytosis and either attenuate or promote inflammation, depending upon the diseas
Externí odkaz:
https://doaj.org/article/95c6201ac4ca43c4917c5c7e3d89744b
Autor:
Jully Gogoi-Tiwari, Vincent Williams, Charlene Babra Waryah, Sangeetha Mathavan, Harish Kumar Tiwari, Paul Costantino, Trilochan Mukkur
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148383 (2016)
Protein A, encoded by the spa gene, is one of the major immune evading MSCRAMM of S. aureus, demonstrated to be prevalent in a significant percentage of clinical bovine mastitis isolates in Australia. Given its' reported significance in biofilm forma
Externí odkaz:
https://doaj.org/article/246cf765bcd44734acbb694b75df1ea2
Autor:
Alan R. Harvey, Colette Moses, Charlene Babra Waryah, Pilar Blancafort, Fiona Nugent, Benjamin Garcia-Bloj
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss, Pp 287-300 (2019)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
PTEN expression is lost in many cancers, and even small changes in PTEN activity affect susceptibility and prognosis in a range of highly aggressive malignancies, such as melanoma and triple-negative breast cancer (TNBC). Loss of PTEN expression occu
Autor:
K. Swaminathan Iyer, Edina Wang, Marck Norret, Benjamin F. Dessauvagie, Diwei Ho, Colette Moses, Anabel Sorolla, Jessica A. Kretzmann, Pilar Blancafort, Amy L. Kretzmann, Nicole M. Smith, Cameron W. Evans, Andrew Redfern, Charlene Babra Waryah, Mark J. Hackett
Publikováno v:
Chemical Science. 10:7718-7727
Aberrant gene expression is a hallmark of cancer. Although transcription is traditionally considered ‘undruggable’, the development of CRISPR-associated protein 9 (Cas9) systems offers enormous potential to rectify cancer-associated transcription
Autor:
Kevin D. G. Pfleger, Wan Jun Tie, Joseph Cursons, Bum-Kyu Lee, Piotr Kozlowski, Edina Wang, Rabab Rashwan, Ciara Duffy, Mohit Jain, Magdalena Ratajska, Wojciech Biernat, Pilar Blancafort, Piotr Czapiewski, Anabel Sorolla, Agustin Sgro, Andrew J. Woo, Christina Curtis, Jeremy Parry, Kim A. Lagerborg, Charlene Babra Waryah, Elizabeth K. M. Johnstone, Jonghwan Kim, Bartosz Wasag, Eleanor A. Woodward, Javier A. Menendez, Nathan J. Pavlos, Emily Golden, Andrew Redfern, Iwona Kardaś, Heng B. See, Elisabet Cuyàs, Adam Gorczyński
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Adipogenesis associated Mth938 domain containing (AAMDC) represents an uncharacterized oncogene amplified in aggressive estrogen receptor-positive breast cancers. We uncover that AAMDC regulates the expression of several metabolic enzymes involved in
Autor:
Jully Gogoi-Tiwari, Doddamane Rathnamma, Avinash S. Bhat, B.M. Akshatha, Bibek Ranjan Shome, V. Nuthanalakshmi, H. A. Upendra, B. H. Veeresh, B.M. Veeregowda, Akhauri Yash Sinha, Charlene Babra Waryah, Nagendra R. Hegde, K. Nithin Prabhu, Shrikrishna Isloor, Raju Sunagar, Raveendra Hegde, S. Sundareshan, Trilochan Mukkur
Publikováno v:
Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases. 41:39
Biofilm formation is an important virulence determinant of Staphylococcus aureus which is a major etiological agent of bovine mastitis. Here, 132 bovine mastitis-associated S. aureus were subjected to biofilm production, antimicrobial susceptibility,
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1767
The completion of genome, epigenome, and transcriptome mapping in multiple cell types has created a demand for precision biomolecular tools that allow researchers to functionally manipulate DNA, reconfigure chromatin structure, and ultimately reshape
Autor:
Nagendra R. Hegde, Paul Costantino, Kelsi Wells, Karina Yui Eto, Modiri Tau, Shrikrishna Isloor, Charlene Babra Waryah, Trilochan Mukkur, Harish Kumar Tiwari, Jully Gogoi-Tiwari
Publikováno v:
Virulence. 6:419-423
Staphylococcus aureus is one of the major contagious pathogens causing bovine mastitis worldwide.1 It causes contagious mastitis resulting either clinical or subclinical mastitis with increase in the number of somatic cell count (SCC) in milk. More t
Autor:
Nigel Chen-Tan, Andreas Vilcinskas, Joshua T. Ravensdale, Jochen Wiesner, Trilochan Mukkur, Jully Gogoi-Tiwari, Dulantha Ulluwishewa, Paul Costantino, Anke Gökçen, Charlene Babra Waryah, Kelsi Wells
Publikováno v:
Microbial drug resistance (Larchmont, N.Y.). 23(3)
Staphylococcus aureus in biofilms is highly resistant to the treatment with antibiotics, to which the planktonic cells are susceptible. This is likely to be due to the biofilm creating a protective barrier that prevents antibiotics from accessing the