Výsledky vyhledávání - "Charla Sweeley"

Exploration of β-turn scaffolding motifs as components of sialyl LeX mimetics and their relevance to P-selectin

Autor: Charla Sweeley, Hartmuth C. Kolb, Grant McNaughton-Smith, Stephen Hanessian, John L. Magnani, Hoan K. Huynh, Beat Ernst, Gurijala V. Reddy

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 8:2803-2808

Monocyclic and bicyclic lactam units representing β-turn surrogates were incorporated into a sialyl Le X structure by replacement of the natural sugar components. Low micromolar activity was found in a new P-selectin binding assay.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e581619e93e1cc71d87dd64e17df05
https://doi.org/10.1016/s0960-894x(98)00500-9

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Activation of protein kinase C isozymes by contractile stimuli in arterial smooth muscle

Autor: C. M. Schworer, Harold A. Singer, Charla Sweeley, Holly A. Benscoter

Publikováno v: Archives of biochemistry and biophysics. 299(2)

Protein kinase C (PKC) has been proposed to be involved in the regulation of vascular smooth muscle (VSM) contractile activity. However, little is known in detail about the activation of this kinase or specific isozymes of this kinase by contractile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabf1cb7ff286b9033207e115fb0e0de
https://pubmed.ncbi.nlm.nih.gov/1444471

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