Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Charlène Rico"'
Publikováno v:
Veterinary and Comparative Oncology. 20:437-448
Canine mammary tumours (CMTs) are the most common neoplasms in intact bitches, and few chemotherapeutic options are available for highly invasive and metastatic tumours. Recent studies have shown the potential involvement of dysregulated Hippo signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd347bc2efc4f4d211b25ba0a5c3d759
https://doi.org/10.1111/vco.12789
https://doi.org/10.1111/vco.12789
Autor:
Derek Boerboom, Martin Morin, Marilène Paquet, Charlène Rico, Nicolas Gévry, Randy L. Johnson, Mayra Tsoi
Publikováno v:
FASEB J
Recent reports suggest that the Hippo signaling pathway influences ovarian follicle development; however, its exact roles remain unknown. Here, we examined the ovarian functions of the Hippo kinases large tumor suppressors (LATS)1 and 2, which serve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6f99cbcd2a54f1161f7e84a2d93e7b
https://doi.org/10.1096/fj.201900609r
https://doi.org/10.1096/fj.201900609r
Publikováno v:
Veterinary and Comparative Oncology. 16:630-635
Canine mammary tumours (CMTs) are common neoplasms in dogs that feature many of the clinical, genetic and molecular characteristics of human breast cancer. Despite their high metastatic potential, few adjuvant chemotherapeutic treatment options exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf79dcb398630be1a5018e42b4bb6de3
https://doi.org/10.1111/vco.12432
https://doi.org/10.1111/vco.12432
Publikováno v:
Veterinary and Comparative Oncology. 16:311-317
Valosin-containing protein (VCP), through its critical role in the maintenance of protein homeostasis, is a promising target for the treatment of several malignancies, including canine lymphoma. CB-5083, a first-in-class VCP inhibitor, exerts cytotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fe3ceaaaae9367c6c3d6dac96ee172
https://doi.org/10.1111/vco.12380
https://doi.org/10.1111/vco.12380
Autor:
Evelyne Lapointe, Marilène Paquet, Atefeh Abedini, Derek Boerboom, Gustavo Zamberlam, Philippe Godin, Charlène Rico, Francesco J. DeMayo
Publikováno v:
Endocrinology. 160(7)
WNT signaling regulates a variety of ovarian processes, including follicle development, granulosa cell (GC) proliferation and differentiation, steroidogenesis, and ovulation. The secreted frizzled-related proteins (SFRPs) comprise a family of WNT sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cabf059ccb1144191ca3f6bccb4f13e
https://pubmed.ncbi.nlm.nih.gov/30942852
https://pubmed.ncbi.nlm.nih.gov/30942852
Autor:
Charlène Rico, Nicolas Gévry, Mayra Tsoi, Barbara C. Vanderhyden, Alexandre Boyer, Marilène Paquet, Riitta Kaarteenaho, Guillaume St-Jean, Bojana Djordjevic, Derek Boerboom, Martin Morin, Atefeh Abedini, Adrien Levasseur, Ilkka Miinalainen
Publikováno v:
Development.
WNT signaling plays essential roles in the development and function of the female reproductive tract. Although crosstalk with the Hippo pathway is a key regulator of WNT signaling, whether Hippo itself plays a role in female reproductive biology rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7518aa6e91330df03ca1d67cfb26e2
https://doi.org/10.1242/dev.180430
https://doi.org/10.1242/dev.180430
Autor:
Charlène Rico, Pascal Mermillod, Laure Calais, Yann Locatelli, Michael J. Bertoldo, Cynthia Frapsauce, Nicolas Duffard, Jérémy Bernard
Publikováno v:
Animal Reproduction Science
Animal Reproduction Science, Elsevier Masson, 2014, 149 (3-4), pp.124-134. ⟨10.1016/j.anireprosci.2014.07.010⟩
Animal Reproduction Science, Elsevier Masson, 2014, 149 (3-4), pp.124-134. ⟨10.1016/j.anireprosci.2014.07.010⟩
The aim of the present study was to establish the presence of BMP type I and II receptor presence in preantral follicles and to investigate the effect of BMP4 supplementation on preantral follicle activation and development during organotypic culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d64f193466f704b0fe79c8837b71f0
https://doi.org/10.1016/j.anireprosci.2014.07.010
https://doi.org/10.1016/j.anireprosci.2014.07.010
Autor:
Marie-Eve Nadeau, Evelyne Lapointe, Derek Boerboom, Vikas Kumar, Marilène Paquet, Marie-Noëlle Laguë, Charlène Rico, Mayra Tsoi, Pavine L.C. Lefèvre, Aurore Dodelet-Devillers
Publikováno v:
Carcinogenesis. 33:2283-2292
Few targeted therapies have been developed for ovarian granulosa cell tumor (GCT), even though it represents 5% of all malignant ovarian tumors in women. As misregulation of PI3K/AKT signaling has been implicated in GCT development, we hypothesized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dfb3a97a3f0043b246763825764a9c
https://doi.org/10.1093/carcin/bgs263
https://doi.org/10.1093/carcin/bgs263
Autor:
Martine Bontoux, Claire Médigue, Danielle Monniaux, Peggy Jarrier, Stéphane Fabre, Charlène Rico, Frédérique Clément
Publikováno v:
Biology of Reproduction. 84:560-571
Anti-Mullerian hormone (AMH) is an endocrine marker that can help predict superovulatory responses to treatments administered to cows for embryo production. However, the optimal time of the estrous cycle at which a blood test should be performed for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83121c7fbe087c3d164e5e14eeb6fb14
https://doi.org/10.1095/biolreprod.110.088187
https://doi.org/10.1095/biolreprod.110.088187
Autor:
Vikas Kumar, Xiang Zhou, Ulrich Boehm, Ying Wang, Daniel J. Bernard, Charlène Rico, Marilène Paquet, Alexandre Boyer, Romain Lambrot, Christophe Céleste, Sarah Kimmins, Derek Boerboom
Publikováno v:
Endocrinology. 156(1)
Although classically considered a WNT signaling intermediary, β-catenin (CTNNB1) can also mediate GnRH induction of gonadotropin β-subunit (Fshb and Lhb) transcription in the murine gonadotrope-like cell line LβT2. Here, we assessed CTNNB1's role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6cd8cb015d00d7944b48353b454e01
https://pubmed.ncbi.nlm.nih.gov/25343272
https://pubmed.ncbi.nlm.nih.gov/25343272