Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Charito S. Buensuceso"'
Publikováno v:
Seminars in Thrombosis and Hemostasis. 30:427-439
The major platelet integrin alpha (IIb)beta (3) is the main receptor involved in platelet functions such as aggregation and spreading on extracellular matrix. Like all other integrins, alpha (IIb)beta (3) is capable of transducing signals both from i
Publikováno v:
Journal of Biological Chemistry. 278:15217-15224
In platelets, bidirectional signaling across integrin alpha(IIb)beta(3) regulates fibrinogen binding, cytoskeletal reorganization, cell aggregation, and spreading. Because these responses may be influenced by the clustering of alpha(IIb)beta(3) heter
Publikováno v:
Journal of Biological Chemistry. 272:19666-19671
Sustained activation of extracellular signal-regulated kinase 1/2 (ERK1/2) is critical for initiating differentiation of the PC12 cell to a sympathetic-like neurone. The neuropeptide, pituitary adenylyl cyclase-activating peptide (PACAP), has been de
Publikováno v:
Biomaterials. 32(36)
Fibrin Pad is a hemostatic pad designed to control surgical-related bleeding. It consists of a fully absorbable composite matrix scaffold coated with human-derived active biologics that immediately form a fibrin clot upon contact with targeted bleedi
Publikováno v:
MRS Proceedings. 1236
Flat coupons prepared from cobalt chromium alloy (CoCr) were modified using different methods (low energy excimer laser processing, electron beam irradiation, and immobilized covalently-bound heparin coating). Human coronary artery endothelial cell (
Autor:
Achim Obergfell, William B. Kiosses, Charito S. Buensuceso, Toshiaki Kawakami, Koji Eto, Elena García Arias-Salgado, Sanford J. Shattil, Alessandra Soriani
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
10 páginas, 9 figuras -- PAGS nros. 644-653
Studies with inhibitors have implicated protein kinase C (PKC) in the adhesive functions of integrin αIIbβ3 in platelets, but the responsible PKC isoforms and mechanisms are unknown. αIIbβ3 intera
Studies with inhibitors have implicated protein kinase C (PKC) in the adhesive functions of integrin αIIbβ3 in platelets, but the responsible PKC isoforms and mechanisms are unknown. αIIbβ3 intera
Publikováno v:
Seminars in thrombosis and hemostasis. 30(4)
The major platelet integrin alpha (IIb)beta (3) is the main receptor involved in platelet functions such as aggregation and spreading on extracellular matrix. Like all other integrins, alpha (IIb)beta (3) is capable of transducing signals both from i
Autor:
Sanford J. Shattil, Attila Mócsai, Koji Eto, Joan S. Brugge, Achim Obergfell, Charito S. Buensuceso, Sheri L. Moores, Clifford A. Lowell
Publikováno v:
The Journal of Cell Biology
Integrins regulate cell adhesion and motility through tyrosine kinases, but initiation of this process is poorly understood. We find here that Src associates constitutively with integrin alphaIIbbeta3 in platelets. Platelet adhesion to fibrinogen cau
Publikováno v:
The Journal of biological chemistry. 275(17)
In studies to define mechanisms of ERK activation in Chinese hamster ovary cells, we have observed an inverse correlation between CRKII-C3G complex formation and ERK activity. That is, we were able to coprecipitate the guanine nucleotide exchange fac
Autor:
Charito S Buensuceso
Publikováno v:
Seminars in Thrombosis & Hemostasis; 2004, Vol. 30 Issue 4, p427-439, 13p