Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Charisse Y-J. Kuo"'
Publikováno v:
International Journal of Translational Medicine, Vol 4, Iss 3, Pp 402-418 (2024)
While existing local therapies partially restore vision loss from diabetic retinopathy (DR), there is currently no reliable treatment to prevent the onset or stop the progression of the disease. This review seeks to explore the inflammatory molecular
Externí odkaz:
https://doaj.org/article/bf156e7da43d476ca458edfa7b709761
Publikováno v:
Future Pharmacology, Vol 3, Iss 3, Pp 612-624 (2023)
The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) protein 3 (NLRP3) inflammasome pathway is believed to mediate chronic inflammation in diabetic retinopathy (DR); however, its impact on the progression of DR remains to be elucid
Externí odkaz:
https://doaj.org/article/66fce5b360ac4b8fa362ecca7138fb52
Publikováno v:
BMC Ophthalmology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Activation of the NOD-like receptor protein 3 (NLRP3) inflammasome pathway has been implicated in Diabetic retinopathy (DR) pathogenesis, but its impact on DR development and progression remains unclear. Therefore, the primary aim of this sy
Externí odkaz:
https://doaj.org/article/e4faf2fec8c24f81ad997c7b0d8b27f0
Autor:
Charisse Y-J. Kuo, Jack J. Maran, Emma G. Jamieson, Ilva D. Rupenthal, Rinki Murphy, Odunayo O. Mugisho
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14471
The aim of this study was to characterize the role of nucleotide-binding oligomerization domain- (NOD-) like receptor (NLR) protein 3 (NLRP3) inflammasome activation in the onset of diabetic retinopathy (DR) using retina and vitreous from donors with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b957d40ddced7cf84b965dda864c44d
Publikováno v:
Acta Diabetologica. 57:13-22
The retinal pigment epithelium (RPE) is an important component of the outer blood–retinal barrier (BRB) that separates the choroid from the rest of the retina. Loss of RPE-mediated BRB integrity is a key feature of diabetic macular oedema (DME), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c0c045f0bbcf363aa0ce57bbb5b261
https://doi.org/10.1007/s00592-019-01352-3
https://doi.org/10.1007/s00592-019-01352-3
Autor:
Odunayo O Mugisho, Ilva D. Rupenthal, Colin R. Green, Avik Shome, Henry H. Louie, Charisse Y J Kuo
Publikováno v:
Experimental eye research. 202
Diabetic retinopathy (DR), the most common ocular complication associated with diabetes, is a chronic vascular and inflammatory disease that leads to vision loss. The inflammasome pathway, a key part of the innate immune system, is required to activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909337a35c3d1453ec4bbb09838b4454
https://pubmed.ncbi.nlm.nih.gov/33285185
https://pubmed.ncbi.nlm.nih.gov/33285185