Digital microfluidic isolation of single cells for -Omics

Autor: Julian Lamanna, Erica Y. Scott, Harrison S. Edwards, M. Dean Chamberlain, Michael D. M. Dryden, Jiaxi Peng, Barbara Mair, Adam Lee, Calvin Chan, Alexandros A. Sklavounos, Austin Heffernan, Farhana Abbas, Charis Lam, Maxwell E. Olson, Jason Moffat, Aaron R. Wheeler

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

Multi-Omic approaches are a powerful way for obtaining in-depth understanding of a cell’s state. Here the authors present DISCO, combining digital microfluidics, laser cell lysis, and artificial intelligence-driven image processing to analyze singl

Externí odkaz: https://doaj.org/article/f14d36deac8249f8ad452834eda79d88

Randomised multicentre effectiveness trial of rapid syndromic testing by panel assay in children presenting to European emergency departments with acute respiratory infections—trial protocol for the ADEQUATE Paediatric trial

Autor: Alexander Ross, Andrew Atkinson, Maarten J Postma, Federica Vanoni, Julia A Bielicki, Fernando Antoñanzas, Herman Goossens, Elias Iosifidis, Emmanuel Roilides, Mark Lyttle, Elia Vitale, Malte Kohns Vasconcelos, Florence Allantaz, Claire Hawksworth, Pablo Rojo, Dalia Dawoud, Surbhi Malhotra-Kumar, Silke Peter, Hanna Renk, Marc Bonten, Manuel Gijon, Maggie Nyirenda Nyang’wa, Thea van Asselt, Anthony Hemeson, Cristina Prat Aymerich, Simon van der Pol, Parthena Savvidou, Sophie Vandepitte, Emma Gardiner, Michelle Clements, Yasmine Yau, Giulio Vecchia, Federica D’Ambrosio, Wietske Bouwman, Marjolein van Esschoten, Frank Leus, David de Pooter, Leen Timbermont, Juan Pablo Rodriguez Ruiz, Benjamin Hommel, Marie Tessonneau, Jean-Louis Tissier, Philippe Cleuziat, Pim van Dorst, Paula Rojas, Marino Gonzales, Harry Heijerman, Henri van Werkhoven, Maria Simitsopoulou, Kalliopi Pantzartzi, Kostas Zarras, Argyro Ftergioti, Maria Kitsou, Aristea Karypiadou, Charis Lampada, Konstantina Charisi, Olga Tsiatsiou, Elsa Chorafa, Elisavet Michailidou, Ann-Kathrin Stiegler, Carmen Junk, Kristina Kiesel, Maren Belschner, Maike Seyfried, Kristina Schmauder, Tobias Walter, Dominic Imort, Fabian Behret, Rahel Berger, Leon Pfeiffer, Emanuela Früh, Elena Robinson, Andrea Marten, Claudia Werner, Rosa Calderón, Fátima Machín, Laura Cabello, Andrea Seoane, Sofía Mesa, Lidia Oviedo, Luisa Barón, Irene Hernández, Lisa Capozzi, Louisa Brock, Cecilia Hultin, Louise F Hill, Alessia Severi Conti, Gianluca Gualco

Publikováno v: BMJ Open, Vol 14, Iss 4 (2024)

Introduction Syndromic panel assays, that is, using one test to simultaneously target multiple pathogens with overlapping signs and symptoms, have been integrated into routine paediatric care over the past decade, mainly for more severely ill and hos

Externí odkaz: https://doaj.org/article/d5c0be897b4147ba974e10f2eee0d1ef

A digital microfluidic system for serological immunoassays in remote settings

Autor: Edward A. Sykes, Alaine Knipes, Nina Marano, Paul M. Chege, Peter Borus, Charis Lam, Maurice Ope, Rosemary Nzunza, Ngina Kisangau, Christopher Dixon, Darius G. Rackus, Eugene Lam, Michael D. M. Dryden, M. Dean Chamberlain, Ryan Fobel, Christian Fobel, Alphonsus H. C. Ng, Paul A. Rota, Mohd Afiq Mohd Asri, Victor Lee, John Wagacha Burton, John Kiogora, Aaron R. Wheeler, Man Ho, Aimee Summers, Heather M. Scobie, Michael Karuingi, Rachael Joseph, Nooman S. Mufti, Julian Lamanna, Mary Njuguna

Publikováno v: Science Translational Medicine. 10

Serosurveys are useful for assessing population susceptibility to vaccine-preventable disease outbreaks. Although at-risk populations in remote areas could benefit from this type of information, they face several logistical barriers to implementation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c270a747259421ba7c3169ec2ca55baa
https://doi.org/10.1126/scitranslmed.aar6076