Výsledky vyhledávání - "Charing C. N. Chong"

‘Potentially curative therapies’ for hepatocellular carcinoma: how many patients can actually be cured?

Autor: Alessandro Cucchetti, Omar Elshaarawy, Guohong Han, Charing C. N. Chong, Carla Serra, Joanne Marie O’Rourke, Richard Crew, Cristina Felicani, Giorgio Ercolani, Tahir Shah, Arndt Vogel, Paul B. S. Lai, Philip J. Johnson

Publikováno v: British Journal of Cancer. 128:1665-1671

Background Treatment of hepatocellular carcinoma (HCC) is predicated on early diagnosis such that ‘curative therapies’ can be successfully applied. The term ‘curative’ is, however, poorly quantitated. We aimed to complement our previous work

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fd28f5323a69af63e473097f652b1cf
https://doi.org/10.1038/s41416-023-02188-z

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A retrospective comparative study of robotic distal pancreatectomy with or without splenic vessel and spleen preservation

Autor: Sunny Y.S. Cheung, Charing C N Chong, Hon Ting Lok, Kit Fai Lee, Eugene Yee Juen Lo, Paul B.S. Lai, John Wong, Andrew K Y Fung

Publikováno v: The Surgeon. 20:129-136

Background Robotic distal pancreatectomy has been accepted to be safe and effective for pancreatic tail lesion. Whether spleen preservation by preserving the splenic vessels with robot assistance is feasible and beneficial remains controversial. Here

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057f3821a2bb76def7f7d034e6046c46
https://doi.org/10.1016/j.surge.2021.02.004

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Liver stiffness measurement predicts short-term and long-term outcomes in patients with hepatocellular carcinoma after curative liver resection

Autor: Ruby Siu-Ting Lau, Kit-Fai Lee, Kandy Kam-Cheung Wong, Grace Lai-Hung Wong, Vincent Wai-Sun Wong, Andrew K Y Fung, Charing C N Chong, John Wong, Eugene Jun-Yee Lo, Henry Lik-Yuen Chan, Philip Ching-Tak Ip, Paul B.S. Lai, Kelvin K. Ng

Publikováno v: The Surgeon. 20:78-84

Hepatocellular carcinoma is one of the commonest cancer in the world. Despite curative resection, recurrence remains the largest challenge. Many risk factors were identified for predicting recurrence, including liver fibrosis and cirrhosis. Transient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5531fb7c34a44388d0aadf278fd8eb2
https://doi.org/10.1016/j.surge.2021.01.004

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Asia-Pacific multicentre randomized trial of laparoscopicversusopen major hepatectomy for hepatocellular carcinoma (AP-LAPO trial)

Autor: Kelvin K C Ng, Charing C N Chong, Kit-Fai Lee, Paul B S Lai, Thomas K C Cheng, Hua-Wei Chen, Bin Yi, Ji-Wei Huang

Publikováno v: BJS Open. 7

BackgroundHepatocellular carcinoma is the sixth most common malignancy in the world. Major hepatectomy (resection of greater than or equal to three liver segments) is needed if a tumour is large or close to major blood vessels. Despite low mortality,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b367d4801d1b4b9887ad8c3e3c07b28
https://doi.org/10.1093/bjsopen/zrac166

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Comparison of Survival Outcomes in Transarterial Ethanol Ablation and Liver Resection for Solitary Hepatocellular Carcinoma ≤ 5 cm in Patients Stratified by Liver Function

Autor: Carmen C.M. Cho, Charing C N Chong, Kit Fai Lee, Joyce W.Y. Hui, Simon C.H. Yu, John Wong, Sunny Y.S. Cheung

Publikováno v: CardioVascular and Interventional Radiology. 45:315-327

PURPOSE To compare the survival outcomes of patients treated with transarterial ethanol ablation (TEA) with those treated with liver resection (LR) for solitary HCC less than 5 cm in diameter, in patients stratified according to liver function using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9769a568d16dfe51b95c458bdf705419
https://doi.org/10.1007/s00270-021-02768-7

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A phase II clinical study on the efficacy and predictive biomarker of pegylated recombinant arginase on hepatocellular carcinoma

Autor: Charing C N Chong, Anthony W.H. Chan, Leung Li, Yat M Lau, Cheuk Man Chu, Tony Mok, Paul N. M. Cheng, Simon C.H. Yu, Angela M Liu, Kelvin K. Ng, Winnie Yeo, Stephen L. Chan, Landon L. Chan

Publikováno v: Investigational New Drugs

Background: Pegylated recombinant human arginase (PEG-BCT-100) is an arginine depleting drug. Preclinical studies showed that HCC is reliant on exogenous arginine for growth due to the under-expression of the arginine regenerating enzymes argininosuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1fd93c2530989f99b6c97af45f5bcb
https://doi.org/10.1007/s10637-021-01111-8

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Comparison of long-term survival outcome after curative hepatectomy between selected patients with non-colorectal and colorectal liver metastasis: A propensity score matching analysis

Autor: H.T. Lok, John Wong, Andrew K Y Fung, Sunny Y.S. Cheung, Charing C N Chong, Kelvin K. Ng, Kit-Fai Lee, Paul B.S. Lai

Publikováno v: Asian Journal of Surgery, Vol 44, Iss 2, Pp 459-464 (2021)

Background Liver resection is an established treatment of choice for colorectal liver metastasis (CLM). However, the role of hepatectomy for non-colorectal liver metastasis (NCLM) is less clear. Patients and method From 2004 to 2017, 264 patients rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8f5dcd1d06640c1494d2c17b0262db
https://doi.org/10.1016/j.asjsur.2020.10.019

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Genetic variation in ABCB5 associates with risk of hepatocellular carcinoma

Autor: Siu T. Cheung, Idy C.Y. Leung, Charing C N Chong, Anthony W.H. Chan, Stephen L. Chan, Philip Chun Yeung, Kelvin K. Ng, Tan T. Cheung, Patrick Ming-Kuen Tang, Paul B.S. Lai

Publikováno v: Journal of Cellular and Molecular Medicine

Expression of ATP‐binding cassette B5 (ABCB5) has been demonstrated to confer chemoresistance, enhance cancer stem cell properties and associate with poor prognosis in hepatocellular carcinoma (HCC). The aim of this study was to evaluate the geneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894ad24e887e6dade3c608426092fe5e
https://doi.org/10.1111/jcmm.15691

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