Výsledky vyhledávání - "Charilaos Megas"

Mutational analysis of TRAF6 reveals a conserved functional role of the RING dimerization interface and a potentially necessary but insufficient role of RING-dependent TRAF6 polyubiquitination towards NF-κB activation

Autor: Charilaos Megas, Dario A. A. Vignali, George Mosialos, Eudoxia Hatzivassiliou, Qian Yin, Elli Marinopoulou, Paul Hadweh

Publikováno v: Cellular Signalling. 23:772-777

TRAF6 is an E3 ubiquitin ligase that plays a pivotal role in the activation of NF-κB by innate and adaptive immunity stimuli. TRAF6 consists of a highly conserved carboxyl terminal TRAF-C domain which is preceded by a coiled coil domain and an amino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811535e8270d2576f1f56293d5a33b3c
https://doi.org/10.1016/j.cellsig.2010.12.004

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