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Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation.

Autor: Eraña, Hasier, Díaz-Domínguez, Carlos M., Charco, Jorge M., Vidal, Enric, González-Miranda, Ezequiel, Pérez-Castro, Miguel A., Piñeiro, Patricia, López-Moreno, Rafael, Sampedro-Torres-Quevedo, Cristina, Fernández-Veiga, Leire, Tasis-Galarza, Juan, Lorenzo, Nuria L., Santini-Santiago, Aileen, Lázaro, Melisa, García-Martínez, Sandra, Gonçalves-Anjo, Nuno, San-Juan-Ansoleaga, Maitena, Galarza-Ahumada, Josu, Fernández-Muñoz, Eva, Giler, Samanta

Publikováno v: Acta Neuropathologica Communications; 9/7/2023, Vol. 11 Issue 1, p1-30, 30p

Detection of chronic wasting disease in mule and white-tailed deer by RT-QuIC analysis of outer ear.

Autor: Ferreira, Natalia C.¹, Charco, Jorge M.², Plagenz, Jakob¹, Orru, Christina D.¹, Denkers, Nathanial D.³, Metrick II, Michael A.¹, Hughson, Andrew G.¹, Griffin, Karen A.⁴, Race, Brent¹, Hoover, Edward A.³, Castilla, Joaquín^2,5, Nichols, Tracy A.⁶, Miller, Michael W.⁴, Caughey, Byron¹ bcaughey@nih.gov

Publikováno v: Scientific Reports. 4/8/2021, Vol. 11 Issue 1, p1-9. 9p.

Analysis of a large case series of fatal familial insomnia to determine tests with the highest diagnostic value

Autor: Kortazar-Zubizarreta, Izaro, Eraña, Hasier, Pereda, Arrate, Charco, Jorge M., Manero-Azua, África, Ruiz-Onandi, Rebeca, Aguirre, Urko, González-Chinchón, Gonzalo, Basque Prionopathy Study Group, Perez de Nanclares, Guiomar, Castilla, Joaquín

Fatal familial insomnia (FFI) is a rare prionopathy with unusually high incidence in the Basque Country. We report detailed data on clinical, diagnostic, histopathological, and biochemical characteristics of a recent FFI case series. The Basque Brain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::6945c3e9ad45e2bda2439cc82b97cab4
https://zenodo.org/record/7428479

Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies.

Autor: Eraña, Hasier^1,2 (AUTHOR), Charco, Jorge M.¹ (AUTHOR), Di Bari, Michele A.³ (AUTHOR), Díaz-Domínguez, Carlos M.¹ (AUTHOR), López-Moreno, Rafael¹ (AUTHOR), Vidal, Enric⁴ (AUTHOR), González-Miranda, Ezequiel¹ (AUTHOR), Pérez-Castro, Miguel A.¹ (AUTHOR), García-Martínez, Sandra^1,2 (AUTHOR), Bravo, Susana⁵ (AUTHOR), Fernández-Borges, Natalia¹ (AUTHOR), Geijo, Mariví⁶ (AUTHOR), D'Agostino, Claudia³ (AUTHOR), Garrido, Joseba⁶ (AUTHOR), Bian, Jifeng⁷ (AUTHOR), König, Anna^8,9 (AUTHOR), Uluca-Yazgi, Boran^8,9 (AUTHOR), Sabate, Raimon^10,11 (AUTHOR), Khaychuk, Vadim⁷ (AUTHOR), Vanni, Ilaria³ (AUTHOR)

Publikováno v: PLoS Pathogens. 10/23/2019, Vol. 15 Issue 10, p1-33. 33p.