Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Charbel Eid"'
Autor:
Anton Valouev, Elena Zotenko, Matthew Snyder, Charbel Eid, Ngan Nguyen, Jun Min, Yupeng He, Ariel Jaimovich, Haley Axelrod, Prashanthi Natarajan, Anna Hartwig, Noam Vardi, Tam Banh, Andrew Kennedy, William Greenleaf, Stefanie Mortimer, Sven Duenwald, Darya Chudova, AmirAli Talasaz
Publikováno v:
Cancer Research. 82:2141-2141
Background: A blood-based cancer screening test must exhibit performance metrics optimized for the cancer of interest based on associated clinical diagnostic pathways and demonstrate an ability to detect disease at an early stage when intervention ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2baa2ae25b9d4081620f5dbd967d96e3
https://doi.org/10.1158/1538-7445.am2022-2141
https://doi.org/10.1158/1538-7445.am2022-2141
Autor:
Anton Valouev, Elena Zotenko, Matthew Snyder, Charbel Eid, Ngan Nguyen, Jun Min, Yupeng He, Ariel Jaimovich, Haley Axelrod, Prashanthi Natarajan, Kathryn Pendleton, Anna Hartwig, Noam Vardi, Tam Banh, Drew Kennedy, William Greenleaf, Stefanie Mortimer, Sven Duenwald, Darya Chudova, AmirAli Talasaz
Publikováno v:
Journal of Clinical Oncology. 40:3542-3542
3542 Background: Cancer screening in asymptomatic individuals who meet guideline criteria has yielded reductions in cancer death rates. However, adherence to screening guidelines remains below targets set forth by leading health-care organizations. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92dd3705060f0c62da634f9e216cb69c
https://doi.org/10.1200/jco.2022.40.16_suppl.3542
https://doi.org/10.1200/jco.2022.40.16_suppl.3542
Autor:
Charbel Eid, Juan G. Santiago
Publikováno v:
Lab on a Chip. 18:11-26
This review discusses research developments and applications of isotachophoresis (ITP) to the initiation, control, and acceleration of chemical reactions, emphasizing reactions involving biomolecular reactants such as nucleic acids, proteins, and liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138da403e9bb28dfd77d96cddb767b90
https://doi.org/10.1039/c7lc00852j
https://doi.org/10.1039/c7lc00852j
Publikováno v:
The Analyst. 142:2094-2099
We present a novel microfluidic device for size-based nucleic acid (NA) fractionation using isotachophoresis (ITP) and an ionic spacer. Our rapid-prototyped laser-cut plastic device has easily modifiable channel dimensions, can process up to 10 μL o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5cdd0c3b5d09fb58d4b1fd829e900c
https://doi.org/10.1039/c7an00431a
https://doi.org/10.1039/c7an00431a
Autor:
Charbel Eid, Juan G. Santiago
Publikováno v:
The Analyst. 142:48-54
We present a new approach which enables lysis, extraction, and detection of inactivated Listeria monocytogenes cells from blood using isotachophoresis (ITP) and recombinase polymerase amplification (RPA). We use an ITP-compatible alkaline and protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f6ce6a969fa7b4f93e343a6b7edb2d
https://doi.org/10.1039/c6an02119k
https://doi.org/10.1039/c6an02119k
Autor:
Juan G. Santiago, Charbel Eid
Publikováno v:
Analytical Chemistry. 88:11352-11357
We present an analytical model useful in the design of peak-mode isotachophoresis (ITP) experiments. The model quantifies sample influx and production rates, the latter in applications where ITP is used to accelerate chemical reactions. We include an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fb9f9e65696f04bd479b020cbd30ea
https://doi.org/10.1021/acs.analchem.6b03467
https://doi.org/10.1021/acs.analchem.6b03467
Autor:
Elena Zotenko, Paul Sample, Oscar Westesson, Jessica Kurata, Jason Dean, Will Greenleaf, Charbel Eid, Haley D. Axelrod, Darya Chudova, Ruth McCole, Ariel Jaimovich, Victoria M. Raymond, Yu Kong, Yupeng He, AmirAli Talasaz, Matthew William Snyder, Mohit Goel, Anna Hartwig
Publikováno v:
Cancer Research. 80:2316-2316
Introduction: A novel non-invasive blood-based cell-free DNA (cfDNA) analysis incorporating genomic and epigenomic assessment has demonstrated high sensitivity and specificity in patients with newly diagnosed colorectal cancer (CRC) (Kim, et al. CCR,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5057963a1be80e5eec8882dc30ef707a
https://doi.org/10.1158/1538-7445.am2020-2316
https://doi.org/10.1158/1538-7445.am2020-2316
Publikováno v:
Analytical chemistry. 87(13)
We present an on-chip electrophoretic assay for rapid protein detection with a SOMAmer (Slow Off-Rate Modified Aptamer) reagent. We used isotachophoresis (ITP) coupled with an ionic spacer to both react and separate SOMAmer-protein complex from free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47ee592aa1562cc153e03c5d4609898
https://pubmed.ncbi.nlm.nih.gov/26024067
https://pubmed.ncbi.nlm.nih.gov/26024067
Publikováno v:
The Analyst. 138:3117
We present an on-chip electrophoretic assay for rapid and high sensitivity nucleic acid (NA) detection. The assay uses isotachophoresis (ITP) to enhance NA hybridization and an ionic spacer molecule to subsequently separate reaction products. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f902b53bad16586c66e0d6efce67e0cb
https://doi.org/10.1039/c3an00374d
https://doi.org/10.1039/c3an00374d