Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Charareh Pourzand"'
Autor:
Elise Abboud, Doha Chrayteh, Nadia Boussetta, Héloise Dalle, Mariangela Malerba, Ting-Di Wu, Morgane Le Gall, Olivier Reelfs, Charareh Pourzand, Mark Mellett, Florence Assan, Hervé Bachelez, Joël Poupon, Selim Aractingi, Sophie Vaulont, Pierre Sohier, Bénédicte Oules, Zoubida Karim, Carole Peyssonnaux
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Psoriasis is a multifactorial, chronic inflammatory skin disease with unresolved questions on its primary events. Iron overload has been described in the epidermis of psoriasis patients, but its relevance remains unknown. We found that the k
Externí odkaz:
https://doaj.org/article/d29cac6e7c934ad798dc63142501910f
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Friedreich’s ataxia (FRDA) is a rare childhood neurologic disorder, affecting 1 in 50,000 Caucasians. The disease is caused by the abnormal expansion of the GAA repeat sequence in intron 1 of the FXN gene, leading to the reduced expression of the m
Externí odkaz:
https://doaj.org/article/13dd17eaca024e55a429ab1271c3c43d
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/5087f96bc5704532b5374ee2186b4f07
Publikováno v:
Molecules, Vol 28, Iss 18, p 6467 (2023)
The chemical nature of intracellular labile iron pools (LIPs) is described. By virtue of the kinetic lability of these pools, it is suggested that the isolation of such species by chromatography methods will not be possible, but rather mass spectrome
Externí odkaz:
https://doaj.org/article/1628d8aa47c74dadacb1fe498870d32a
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Iron is a double-edged sword. It is vital for all that’s living, yet its deficiency or overload can be fatal. In humans, iron homeostasis is tightly regulated at both cellular and systemic levels. Extracellular vesicles (EVs), now known as major pl
Externí odkaz:
https://doaj.org/article/05aaead17373430f8e8f7cc99d853263
Autor:
Vega Widya Karisma, Wei Wu, Mingxing Lei, Huawen Liu, Muhammad Farrukh Nisar, Matthew D. Lloyd, Charareh Pourzand, Julia Li Zhong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Light has attracted special attention as a stimulus for triggered drug delivery systems (DDS) due to its intrinsic features of being spatially and temporally tunable. Ultraviolet A (UVA) radiation has recently been used as a source of external light
Externí odkaz:
https://doaj.org/article/2daa0fbbf286444d933909b4b55a1937
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 471 (2022)
Reactive oxygen species (ROS) are necessary for normal cell signaling and the antimicrobial defense of the skin. However excess production of ROS can disrupt the cellular redox balance and overwhelm the cellular antioxidant (AO) capacity, leading to
Externí odkaz:
https://doaj.org/article/8eab3d601a5240c8a939aaf15b628d79
Publikováno v:
Pharmaceutics, Vol 3, Iss 2, Pp 125-140 (2011)
Gene silencing by siRNA (synthetic dsRNA of 21-25 nucleotides) is a well established biological tool in gene expression studies and has a promising therapeutic potential for difficult-to-treat diseases. Five fatty acids of various chain length and ox
Externí odkaz:
https://doaj.org/article/b0becfcca2894d21905a671c7e0b8397
Publikováno v:
ACS Bio & Med Chem Au. 2:642-654
Publikováno v:
Biochemical Society Transactions. 50:975-985
5-Aminolevulinic acid-based photodynamic therapy (ALA-PDT) was first implemented over three decades ago and has since been mainly part of clinical practice for the management of pre-cancerous and cancerous skin lesions. Photodynamic therapy relies on