Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Charalampos Labrakakis"'
Autor:
Despoina Liang, Charalampos Labrakakis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9185 (2024)
The insular cortex is an important hub for sensory and emotional integration. It is one of the areas consistently found activated during pain. While the insular’s connections to the limbic system might play a role in the aversive and emotional comp
Externí odkaz:
https://doaj.org/article/9c017d9cad974532af4aed60f405f202
Publikováno v:
Frontiers in Pain Research, Vol 4 (2024)
Neuropathic pain, a type of chronic pain caused by injury or disease of the somatosensory system, affects ∼10% of the general population and is difficult to treat. It is strongly associated with mood disorder comorbidities and impairs quality of li
Externí odkaz:
https://doaj.org/article/6b0de167398e4e639a7dcb453a942f81
Autor:
Nikolaos P. Tzavellas, Konstantinos I. Tsamis, Andreas P. Katsenos, Athena S. Davri, Yannis V. Simos, Ilias P. Nikas, Stefanos Bellos, Panagiotis Lekkas, Foivos S. Kanellos, Spyridon Konitsiotis, Charalampos Labrakakis, Patra Vezyraki, Dimitrios Peschos
Publikováno v:
Cells, Vol 13, Iss 5, p 434 (2024)
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder, yet its underlying causes remain elusive. The conventional perspective on disease pathogenesis attributes alterations in neuronal excitability to molecular changes resulting
Externí odkaz:
https://doaj.org/article/6729a928487d42e69274516b192c8ad8
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/a9de4fecd2a44dd3b2dc60dc4a3151d0
Autor:
Charalampos Labrakakis
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5736 (2023)
The transition from normal to chronic pain is believed to involve alterations in several brain areas that participate in the perception of pain. These plastic changes are then responsible for aberrant pain perception and comorbidities. The insular co
Externí odkaz:
https://doaj.org/article/7f463cbfab3149be8ffc327d174640b2
Autor:
Louis-Etienne Lorenzo, Agnieszka A. Zurek, Jimena Perez-Sanchez, Irene Lecker, Robert P. Bonin, Erica M. Bridgwater, Charalampos Labrakakis, Yves De Koninck, Beverley A. Orser
Publikováno v:
Journal of Neuroscience Research. 95:1307-1318
Neuronal inhibition mediated by GABAA receptors constrains nociceptive processing in the spinal cord, and loss of GABAergic inhibition can produce allodynia and hyperalgesia. Extrasynaptic α5 subunit-containing GABAA receptors (α5GABAA Rs) generate
Autor:
Jimena, Perez-Sanchez, Louis-Etienne, Lorenzo, Irene, Lecker, Agnieszka A, Zurek, Charalampos, Labrakakis, Erica M, Bridgwater, Beverley A, Orser, Yves, De Koninck, Robert P, Bonin
Publikováno v:
Journal of neuroscience research. 95(6)
Neuronal inhibition mediated by GABA
Autor:
Liang, Despoina1 (AUTHOR), Labrakakis, Charalampos1,2 (AUTHOR) clabrak@uoi.gr
Publikováno v:
International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 17, p9185. 15p.
Publikováno v:
Neuroscience. 129:35-48
Dorsal root ganglion neurons express functional AMPA and kainate receptors near their central terminals. Activation of these receptors causes a decrease in glutamate release during action potential evoked synaptic transmission. Due to differences in
Publikováno v:
European Journal of Neuroscience. 10:2153-2162
Cells from major types of gliomas, i.e. oligodendrogliomas and glioblastomas, are able to generate action potentials upon a current injection similar to neurons (Patt et al. (1996) Neuroscience, 71, 601-611; Labrakakis et al. (1997b) J. Neuropath. Ex