Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Charalampia, Ioannou"'
Autor:
Georgia Ragia, Anthi Maslarinou, Natalia Atzemian, Eirini Biziota, Triantafyllia Koukaki, Charalampia Ioannou, Ioanna Balgkouranidou, George Kolios, Stylianos Kakolyris, Nikolaos Xenidis, Kyriakos Amarantidis, Vangelis G. Manolopoulos
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Dihydropyrimidine dehydrogenase (DPD), encoded by DPYD gene, is the rate-limiting enzyme responsible for fluoropyrimidine (FP) catabolism. DPYD gene variants seriously affect DPD activity and are well validated predictors of FP-associat
Externí odkaz:
https://doaj.org/article/75b50404c6774ad3bb61b20114815f61
Autor:
Charalampia Ioannou, Georgia Ragia, Ioanna Balgkouranidou, Nikolaos Xenidis, Kyriakos Amarantidis, Triantafyllia Koukaki, Eirini Biziota, Stylianos Kakolyris, Vangelis G. Manolopoulos
Publikováno v:
Drug Metabolism and Personalized Therapy. 37:323-327
Objectives The fluoropyrimidine derivatives 5-Fluorouracil and Capecitabine are widely used for the treatment of solid tumors. Fluoropyrimidine metabolism involves a cascade of different enzymes, including MTHFR enzyme. MTHFR c.665C>T polymorphism, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6db54181f8243352416fbbb228d2973b
https://doi.org/10.1515/dmpt-2021-0219
https://doi.org/10.1515/dmpt-2021-0219
Autor:
Vangelis G. Manolopoulos, Charalampia Ioannou, Triantafyllia Koukaki, Nikolaos Xenidis, Ioanna Balgkouranidou, Stylianos Kakolyris, Eirini Biziota, Georgia Ragia, K. Amarantidis
Publikováno v:
Pharmacogenomics. 22:669-680
Aim: TYMS gene encodes for TS enzyme involved in 5-fluorouracil (5-FU) and capecitabine (CAP) metabolism. This study assessed the association of TYMS-TSER and 3RG>C polymorphisms with 5-FU/CAP adverse event (AE) incidence. Materials & methods: TYMS-T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41bc79885e915ff100570c2f8f8f2487
https://doi.org/10.2217/pgs-2021-0031
https://doi.org/10.2217/pgs-2021-0031
Autor:
Charalampia, Ioannou, Georgia, Ragia, Ioanna, Balgkouranidou, Nikolaos, Xenidis, Kyriakos, Amarantidis, Triantafyllia, Koukaki, Eirini, Biziota, Stylianos, Kakolyris, Vangelis G, Manolopoulos
Publikováno v:
Pharmacogenomics. 22(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::747289d5cd883d5e2ec2a719b3a45103
https://pubmed.ncbi.nlm.nih.gov/34100299
https://pubmed.ncbi.nlm.nih.gov/34100299
Publikováno v:
Drug metabolism and personalized therapyReferences.
Objectives Hypoglycemia is the most common adverse effect of sulfonylureas (SUs) and a major concern when using these drugs. Transcription factor 7-like 2 (TCF7L2) rs7903146 C>T polymorphism is an established and well characterized genetic marker of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f730575da15075663b3775bbc7bd27af
https://pubmed.ncbi.nlm.nih.gov/33780196
https://pubmed.ncbi.nlm.nih.gov/33780196