Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Charalambos D Partidos"'
Autor:
Fiona R Strouts, Stephen J Popper, Charalambos D Partidos, Dan T Stinchcomb, Jorge E Osorio, David A Relman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 5, p e0004731 (2016)
The development of a vaccine against dengue faces unique challenges, including the complexity of the immune responses to the four antigenically distinct serotypes. Genome-wide transcriptional profiling provides insight into the pathways and molecular
Externí odkaz:
https://doaj.org/article/ca20d7c1be1d49999f9022bc326aaa54
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e2970 (2014)
Chikungunya virus (CHIKV) is a re-emerging arbovirus associated with febrile illness often accompanied by rash and arthralgia that may persist for several years. Outbreaks are associated with high morbidity and create a public health challenge for co
Externí odkaz:
https://doaj.org/article/97e7bbe7680743c0aa1f4a9d4afa45b3
Autor:
Shi-Hsia Hwa, Yock Ann Lee, Joseph N Brewoo, Charalambos D Partidos, Jorge E Osorio, Joseph D Santangelo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 11, p e2538 (2013)
Human enterovirus 71 (EV71) is a significant cause of morbidity and mortality from Hand, Foot and Mouth Disease (HFMD) and neurological complications, particularly in young children in the Asia-Pacific region. There are no vaccines or antiviral thera
Externí odkaz:
https://doaj.org/article/eeb616478f0b4a30941c4fb365f20f6c
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59501 (2013)
Non-polio enteroviruses, including enterovirus 71 (EV71), have caused severe and fatal cases of hand, foot and mouth disease (HFMD) in the Asia-Pacific region. The development of a vaccine or antiviral against these pathogens has been hampered by the
Externí odkaz:
https://doaj.org/article/49b6499375cc44eab595eaef56ab7a89
Autor:
Kenneth Plante, Eryu Wang, Charalambos D Partidos, James Weger, Rodion Gorchakov, Konstantin Tsetsarkin, Erin M Borland, Ann M Powers, Robert Seymour, Dan T Stinchcomb, Jorge E Osorio, Ilya Frolov, Scott C Weaver
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002142 (2011)
Chikungunya virus (CHIKV) is a reemerging mosquito-borne pathogen that has recently caused devastating urban epidemics of severe and sometimes chronic arthralgia. As with most other mosquito-borne viral diseases, control relies on reducing mosquito p
Externí odkaz:
https://doaj.org/article/eac4c566b2654d0ab41db960f375abb0
Autor:
Ralph S. Baric, Jorge E. Osorio, Charalambos D. Partidos, Jesica Swanstrom, Hansi Dean, Douglas G. Widman, Sandra Henein, Boyd Yount, Jessica A. Plante, Emily N. Gallichotte, Aravinda M. de Silva
Publikováno v:
The Journal of Infectious Diseases. 217:1932-1941
BACKGROUND: Dengue virus serotypes 1-4 (DENV-1-4) are the most common vector-borne viral pathogens of humans and the etiological agents of dengue fever and dengue hemorrhagic syndrome. A live-attenuated tetravalent dengue vaccine (TDV) developed by T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a98b8a47b9a7ddd363bd107e407d669
https://doi.org/10.1093/infdis/jiy063
https://doi.org/10.1093/infdis/jiy063
Publikováno v:
Vaccine. 33:7112-7120
Dengue is a significant threat to public health worldwide. Currently, there are no licensed vaccines available for dengue. Takeda Vaccines Inc. is developing a live, attenuated tetravalent dengue vaccine candidate (TDV) that consists of an attenuated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff331b2e7fcc08a4811141e2270386d
https://doi.org/10.1016/j.vaccine.2015.11.022
https://doi.org/10.1016/j.vaccine.2015.11.022
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 5919-5932 (2015)
Viruses; Volume 7; Issue 11; Pages: 5919-5932
Viruses
Viruses; Volume 7; Issue 11; Pages: 5919-5932
Viruses
Hand, foot, and mouth disease (HFMD) has recently emerged as a major public health concern across the Asian-Pacific region. Enterovirus 71 (EV71) and Coxsackievirus A16 (CVA16) are the primary causative agents of HFMD, but other members of the Entero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::293def251a39d7eac973423efc7c2cc7
https://doi.org/10.3390/v7112916
https://doi.org/10.3390/v7112916
Publikováno v:
Journal of Infectious Diseases. 212:1618-1628
We are developing a live-attenuated tetravalent dengue vaccine (TDV) candidate based on an attenuated dengue 2 virus (TDV-2) and 3 chimeric viruses containing the premembrane and envelope genes of dengue viruses (DENVs) -1, -3, and -4 expressed in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3dfbd2d13c8270809c1bde2e8b1f9ed
https://doi.org/10.1093/infdis/jiv258
https://doi.org/10.1093/infdis/jiv258
Publikováno v:
Trends in Pharmacological Sciences
Trends in Pharmacological Sciences, 2017, 38 (9), pp.771-793. ⟨10.1016/j.tips.2017.06.002⟩
Trends in Pharmacological Sciences, 2017, 38 (9), pp.771-793. ⟨10.1016/j.tips.2017.06.002⟩
Adjuvants incorporated in prophylactic and/or therapeutic vaccine formulations impact vaccine efficacy by enhancing, modulating, and/or prolonging the immune response. In addition, they reduce antigen concentration and the number of immunizations req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e48858d3a7d5c3d20c6347e26ecda08
https://hal.archives-ouvertes.fr/hal-02927743
https://hal.archives-ouvertes.fr/hal-02927743
