Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Charalabos Antonatos"'
Autor:
Charalabos Antonatos, Fotios Koskeridis, Christiana M. Ralliou, Evangelos Evangelou, Katerina Grafanaki, Sophia Georgiou, Konstantinos K. Tsilidis, Ioanna Tzoulaki, Yiannis Vasilopoulos
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionPolygenic Risk Scores (PRS) are an emerging tool for predicting an individual’s genetic risk to a complex trait. Several methods have been proposed to construct and calculate these scores. Here, we develop a biologically driven PRS usin
Externí odkaz:
https://doaj.org/article/44a8427a92cc4ffd80b60f314286e6e7
Autor:
Panagiotis Xiropotamos, Foteini Papageorgiou, Haris Manousaki, Charalampos Sinnis, Charalabos Antonatos, Yiannis Vasilopoulos, Georgios K. Georgakilas
Publikováno v:
Biology, Vol 13, Iss 7, p 492 (2024)
With the advent of next-generation sequencing (NGS), experimental techniques that capture the biological significance of DNA loci or RNA molecules have emerged as fundamental tools for studying the epigenome and transcriptional regulation on a genome
Externí odkaz:
https://doaj.org/article/7bfca7e16791475192e582f588a0540a
Autor:
Johannes Reiner G. Asio, Janice S. Garcia, Charalabos Antonatos, Janice B. Sevilla-Nastor, Lorele C. Trinidad
Publikováno v:
Emerging Contaminants, Vol 9, Iss 1, Pp 100205- (2023)
Due to its ubiquitous presence in the environment and the lack of a scientific consensus regarding the environmental safety of the widely used anionic surfactant Sodium Lauryl Sulfate (CAS No: 151-21-3), a systematic literature review and thematic an
Externí odkaz:
https://doaj.org/article/03d2ab519e624aadb0676eb71edb4fba
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7090 (2023)
The emergence of high-throughput approaches has had a profound impact on personalized medicine, evolving the identification of inheritable variation to trajectory analyses of transient states and paving the way for the unveiling of response biomarker
Externí odkaz:
https://doaj.org/article/293573d714cd47c6a015f219743d5986
Autor:
Charalabos Antonatos, Katerina Grafanaki, Paschalia Asmenoudi, Panagiotis Xiropotamos, Paraskevi Nani, Georgios K. Georgakilas, Sophia Georgiou, Yiannis Vasilopoulos
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1934 (2022)
Despite the increasing research and clinical interest in the predisposition of psoriasis, a chronic inflammatory skin disease, the multitude of genetic and environmental factors involved in its pathogenesis remain unclear. This complexity is further
Externí odkaz:
https://doaj.org/article/3217a40caf9b4806b587e3cdbd365370
Autor:
Eleana F. Stavrou, Fani Chatzopoulou, Charalabos Antonatos, Panagiota Pappa, Eutychia Makridou, Konstantinos Oikonomou, Andreas Kapsoritakis, Petros S. Potamianos, Konstantinos Karmiris, Charalambos Tzathas, Dimitris Chatzidimitriou, Ioannis S. Vizirianakis, Yiannis Vasilopoulos
Publikováno v:
Pharmacogenetics and Genomics. 32:235-241
This study explores the potential of gene polymorphisms in the canonical and noncanonical NF-kB signaling pathway as a prediction biomarker of anti-tumor necrosis factor (TNF)α response in Crohn's patients.A total of 109 Greek patients with Crohn's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b8a68255b663ac597fb8e3c45bdc31
https://doi.org/10.1097/fpc.0000000000000471
https://doi.org/10.1097/fpc.0000000000000471
Despite the abundance of epidemiological evidence for the high comorbid rate between psoriasis and obesity, systematic approaches on common inflammatory mechanisms have not been adequately explored. We performed a meta-analysis of publicly available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a57aa26bb422397cdcf5902cd4a2718
https://doi.org/10.21203/rs.3.rs-2852103/v1
https://doi.org/10.21203/rs.3.rs-2852103/v1
Autor:
Paraskevi Nani, Melpomeni Ladopoulou, Evgenia H. Papaioannou, Evangelia D. Papagianni, Charalabos Antonatos, Panagiotis Xiropotamos, Andreas Kapsoritakis, Petros S. Potamianos, Konstantinos Karmiris, Charalambos Tzathas, Aikaterini Patsatsi, Elisavet Lazaridou, Efterpi Zafiriou, Angeliki Roussaki-Schulze, Sophia Georgiou, Katerina Grafanaki, Georgios K. Georgakilas, Yiannis Vasilopoulos
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 445
Volume 14
Issue 2
Pages: 445
The clinical heterogeneity regarding the response profile of the antitumor necrosis factor (anti-TNF) in patients with Crohn’s disease (CD) and psoriasis (PsO) is attributed, amongst others, to genetic factors that influence the regulatory mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4e047051978e8b2d118cf1c64b5e82
Autor:
Charalabos Antonatos, Aikaterini Patsatsi, Efterpi Zafiriou, Eleana F. Stavrou, Andreas Liaropoulos, Aikaterini Kyriakoy, Evangelos Evangelou, Danai Digka, Angeliki Roussaki-Schulze, Dimitris Sotiriadis, Sophia Georgiou, Katerina Grafanaki, Nicholas Κ. Moschonas, Yiannis Vasilopoulos
Publikováno v:
The pharmacogenomics journal.
Although cyclosporine comprises a well-established systemic therapy for psoriasis, patients show important heterogeneity in their treatment response. The aim of our study was the pharmacogenetic analysis of 200 Greek patients with psoriasis based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b8a5caf9adcb623070e21268bd8308
https://pubmed.ncbi.nlm.nih.gov/36229649
https://pubmed.ncbi.nlm.nih.gov/36229649
Autor:
Evangelos Evangelou, Yiannis Vasilopoulos, Charalabos Antonatos, Mariza Panoutsopoulou, Georgios Georgakilas
Publikováno v:
Genes; Volume 13; Issue 5; Pages: 776
While anti-TNFα has been established as an effective therapeutic approach for several autoimmune diseases, results from clinical trials have uncovered heterogeneous patients’ response to therapy. Here, we conducted a meta-analysis on the publicly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d1d83c5e0be02b5e9c47f9c3381ae6