Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Chaquip D. Neto"'
Autor:
BIANCA B. COSTA, JESSICA L.D. GIANELLI, THAMYRIS A. MOREIRA, ANGELICA R. SOARES, BIANCA F. GLAUSER, PAULO A.S. MOURÃO, CHAQUIP D. NETO, CINTHIA M. BARROS, LEONARDO P. CINELLI
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 95, Iss 2 (2023)
Abstract The number of deaths associated with cardiovascular diseases (CVD) increases every year, leading to an intense search for new compounds that may be employed as anticoagulants. One of the classes of bioprospected molecules comprises sulfated
Externí odkaz:
https://doaj.org/article/bcacb1690fe34b73a7c0fc6e10bff059
Autor:
Chaquip D. Neto, François Noël, Paulo R. R. Costa, Fernanda Leitão, Paulo Henrique Cotrim Pimenta, Elisa Suzana Carneiro Pôças, Alcides J. M. da Silva, Natália Araújo Touza
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:8801-8805
The molecular mechanisms involved in Na+,K+-ATPase inhibition by 2-methoxy-3,8,9-trihydroxy coumestan were investigated. We show that this compound decreases the free sulfydryl groups present in the enzyme and that its inhibitory effect is prevented