Výsledky vyhledávání - "Chappell, W. H."

Productive Replication of Human Papillomavirus 31 Requires DNA Repair Factor Nbs1

Autor: Anacker, D. C., Gautam, D., Gillespie, K. A., Moody, C. A., Chappell, W. H.

Activation of the ATM (ataxia telangiectasia-mutated kinase)-dependent DNA damage response (DDR) is necessary for productive replication of human papillomavirus 31 (HPV31). We previously found that DNA repair and homologous recombination (HR) factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07207821a04505bba9403fe3863fc4d8

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Targeting the RAF/MEK/ERK, PI3K/AKT and P53 pathways in hematopoietic drug resistance

Autor: McCubrey J. A., Steelman L. S., Franklin R. A., Abrams S. L., Chappell W. H., Wong E. W., Lehmann B. D., Terrian D. M., Basecke J., Stivala F., Libra M., EVANGELISTI, CAMILLA, MARTELLI, ALBERTO MARIA

We have presented data which documents the importance of the Raf>MEK>ERK and PI3K>Akt pathways in the development of drug resistance in hematopoietic cells. Further understanding of how these pathways interact and induce drug resistance could result

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::25b54197696fa3e8cd3a40aa91272c5b
http://hdl.handle.net/11585/46797

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