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Akademický článek

MiR-35 buffers apoptosis thresholds in the C. elegans germline by antagonizing both MAPK and core apoptosis pathways.

Autor: Tran AT; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; Human Health Therapeutics, National Research Council Canada, 100 Sussex Drive, Ottawa, ON, K1N 5A2, Canada., Chapman EM; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Flamand MN; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.; Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA., Yu B; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada., Krempel SJ; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Duchaine TF; Department of Biochemistry, McGill University, Montreal, QC, H3A 1A3, Canada.; Division of Experimental Medicine & Goodman Cancer Research Center, McGill University, Montreal, QC, H3A 1A3, Canada., Eroglu M; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Derry WB; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada. brent.derry@sickkids.ca.; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada. brent.derry@sickkids.ca.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2019 Dec; Vol. 26 (12), pp. 2637-2651. Date of Electronic Publication: 2019 Apr 05.

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Akademický článek

A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis.

Autor: Chapman EM; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada.; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, M5G 0A4, ON, Canada., Lant B; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, M5G 0A4, ON, Canada., Ohashi Y; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada., Yu B; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, M5G 0A4, ON, Canada., Schertzberg M; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada., Go C; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada.; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Dogra D; Institute for Biochemistry and Biology, Potsdam University, Potsdam, 14476, Germany., Koskimäki J; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine, Chicago, IL, 60637, USA., Girard R; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine, Chicago, IL, 60637, USA., Li Y; University of Chicago Center for Research Informatics, The University of Chicago, Chicago, IL, 60637, USA., Fraser AG; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada.; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada., Awad IA; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine, Chicago, IL, 60637, USA., Abdelilah-Seyfried S; Institute for Biochemistry and Biology, Potsdam University, Potsdam, 14476, Germany., Gingras AC; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada.; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Derry WB; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada. brent.derry@sickkids.ca.; Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, M5G 0A4, ON, Canada. brent.derry@sickkids.ca.

Publikováno v: Nature communications [Nat Commun] 2019 Apr 17; Vol. 10 (1), pp. 1791. Date of Electronic Publication: 2019 Apr 17.

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Akademický článek

Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes.

Autor: Koskimäki J; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Girard R; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Li Y; Center for Research Informatics, The University of Chicago, Chicago, Illinois, USA., Saadat L; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Zeineddine HA; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Lightle R; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Moore T; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Lyne S; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Avner K; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Shenkar R; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Cao Y; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Shi C; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Polster SP; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Zhang D; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Carrión-Penagos J; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Romanos S; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA., Fonseca G; Department of Cellular and Molecular Medicine and., Lopez-Ramirez MA; Department of Medicine, UCSD, La Jolla, California, USA., Chapman EM; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Popiel E; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Tang AT; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Akers A; Angioma Alliance, Norfolk, Virginia, USA., Faber P; University of Chicago Genomics Facility, The University of Chicago, Chicago, Illinois, USA., Andrade J; Center for Research Informatics, The University of Chicago, Chicago, Illinois, USA., Ginsberg M; Department of Medicine, UCSD, La Jolla, California, USA., Derry WB; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Toronto, Ontario, Canada., Kahn ML; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Marchuk DA; The Molecular Genetics and Microbiology Department, Duke University Medical Center, Durham, North Carolina, USA., Awad IA; Neurovascular Surgery Program, Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA.

Publikováno v: JCI insight [JCI Insight] 2019 Feb 07; Vol. 4 (3). Date of Electronic Publication: 2019 Feb 07.

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