Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons.

Autor: Subedi, Ashok^1,2 (AUTHOR), Etemad, Asieh¹ (AUTHOR), Tiwari, Aadhya¹ (AUTHOR), Huang, Yuying³ (AUTHOR), Chatterjee, Biji¹ (AUTHOR), McLeod, Samantha M.¹ (AUTHOR), Lu, Yungang^1,3 (AUTHOR), Gonzalez, DiAngelo¹ (AUTHOR), Ghosh, Krishna³ (AUTHOR), Sirito, Mario¹ (AUTHOR), Singh, Sanjay K.⁴ (AUTHOR), Ruiz, Elisa⁵ (AUTHOR), Grimm, Sandra L.⁵ (AUTHOR), Coarfa, Cristian⁵ (AUTHOR), Pan, Hui-Lin³ (AUTHOR) huilinpan@mdanderson.org, Majumder, Sadhan¹ (AUTHOR) smajumder@mdanderson.org

Publikováno v: Scientific Reports. 11/4/2024, Vol. 14 Issue 1, p1-11. 11p.

Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase.

Autor: Keith JM; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA. Electronic address: jkeith@its.jnj.com., Jones W; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Pierce JM; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Seierstad M; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Palmer JA; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Webb M; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Karbarz M; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Scott BP; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Wilson SJ; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Luo L; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Wennerholm M; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Chang L; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Rizzolio M; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Rynberg R; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Chaplan S; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA., Guy Breitenbucher J; Janssen Pharmaceutical Companies of Johnson & Johnson, L.L.C., 3210 Merryfield Row, San Diego, CA 92121, USA.

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Oct 15; Vol. 30 (20), pp. 127463. Date of Electronic Publication: 2020 Aug 09.

Targeting TANK-binding kinase 1 attenuates painful diabetic neuropathy via inhibiting microglia pyroptosis.

Autor: Liao, Qinming¹ (AUTHOR), Yang, Yimei^1,2 (AUTHOR), Li, Yilu¹ (AUTHOR), Zhang, Jun³ (AUTHOR), Fan, Keke⁴ (AUTHOR), Guo, Yihao⁵ (AUTHOR), Chen, Jun¹ (AUTHOR), Chen, Yinhao¹ (AUTHOR), Zhu, Pian^5,6 (AUTHOR), Huang, Lijin^1,2 (AUTHOR) hlj193@139.com, Liu, Zhongjie^4,5 (AUTHOR) 13580562690@163.com

Publikováno v: Cell Communication & Signaling. 7/19/2024, Vol. 22 Issue 1, p1-17. 17p.

Electroacupuncture improves allodynia and central sensitization via modulation of microglial activation associated P2X4R and inflammation in a rat model of migraine.

Autor: Zhou, Min^1,2 (AUTHOR), Pang, Fang² (AUTHOR), Liao, Dongmei² (AUTHOR), Yang, Yunhao² (AUTHOR), Wang, Ying³ (AUTHOR), Yang, Zhuxin² (AUTHOR), He, Xinlu² (AUTHOR), Tang, Chenglin³ (AUTHOR) tangchenglin@cqmu.edu.cn

Publikováno v: Molecular Pain. 5/29/2024, p1-15. 15p.

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