Zobrazeno 1 - 10
of 484
pro vyhledávání: '"Chaplain, Mark"'
The transition from the epithelial to mesenchymal phenotype and its reverse (from mesenchymal to epithelial) are crucial processes necessary for the progression and spread of cancer. In this paper, we investigate how phenotypic switching at the cance
Externí odkaz:
http://arxiv.org/abs/2305.14388
Neovascularisation is essential for tissue development and regeneration, in addition to playing a key role in pathological settings such as ischemia and tumour development. Experimental findings in the past two decades have led to the identification
Externí odkaz:
http://arxiv.org/abs/2105.11221
Publikováno v:
In Journal of Computational Science January 2024 75
Mechanochemical models of pattern formation in biological tissues have been used to study a variety of biomedical systems and describe the physical interactions between cells and their local surroundings. These models generally consist of a balance e
Externí odkaz:
http://arxiv.org/abs/2009.10953
Since its introduction in 1952, Turing's (pre-)pattern theory ("the chemical basis of morphogenesis") has been widely applied to a number of areas in developmental biology. The related pattern formation models normally comprise a system of reaction-d
Externí odkaz:
http://arxiv.org/abs/2007.04195
Autor:
Bellomo, Nicola, Bingham, Richard, Chaplain, Mark A. J., Dosi, Giovanni, Forni, Guido, Knopoff, Damian A., Lowengrub, John, Twarock, Reidun, Virgillito, Maria Enrica
This paper is devoted to the multidisciplinary modelling of a pandemic initiated by an aggressive virus, specifically the so-called \textit{SARS--CoV--2 Severe Acute Respiratory Syndrome, corona virus n.2}. The study is developed within a multiscale
Externí odkaz:
http://arxiv.org/abs/2006.03915
We consider a mathematical model for the evolutionary dynamics of tumour cells in vascularised tumours under chemotherapy. The model comprises a system of coupled partial integro-differential equations for the phenotypic distribution of tumour cells,
Externí odkaz:
http://arxiv.org/abs/1912.06381
Rheumatoid arthritis is a chronic autoimmune disease that is a major public health challenge. The disease is characterised by inflammation of synovial joints and cartilage erosion, which leads to chronic pain, poor life quality and, in some cases, pr
Externí odkaz:
http://arxiv.org/abs/1911.09035
We present a mathematical study of the emergence of phenotypic heterogeneity in vascularised tumours. Our study is based on formal asymptotic analysis and numerical simulations of a system of non-local parabolic equations that describes the phenotypi
Externí odkaz:
http://arxiv.org/abs/1910.08566
Spatial interactions between cancer and immune cells, as well as the recognition of tumour antigens by cells of the immune system, play a key role in the immune response against solid tumours. The existing mathematical models generally focus only on
Externí odkaz:
http://arxiv.org/abs/1904.02979