Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease

Autor: Hayase, Eiko, Hayase, Tomo, Jamal, Mohamed A., Miyama, Takahiko, Chang, Chia-Chi, Ortega, Miriam R., Ahmed, Saira S., Karmouch, Jennifer L., Sanchez, Christopher A., Brown, Alexandria N., El-Himri, Rawan K., Flores, Ivonne I., McDaniel, Lauren K., Pham, Dung, Halsey, Taylor, Frenk, Annette C., Chapa, Valerie A., Heckel, Brooke E., Jin, Yimei, Tsai, Wen-Bin, Prasad, Rishika, Tan, Lin, Veillon, Lucas, Ajami, Nadim J., Wargo, Jennifer A., Galloway-Peña, Jessica, Shelburne, Samuel, Chemaly, Roy F., Davey, Lauren, Glowacki, Robert W.P., Liu, Chen, Rondon, Gabriela, Alousi, Amin M., Molldrem, Jeffrey J., Champlin, Richard E., Shpall, Elizabeth J., Valdivia, Raphael H., Martens, Eric C., Lorenzi, Philip L., Jenq, Robert R.

Publikováno v: In Cell 29 September 2022 185(20):3705-3719

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Bacteroides ovatus alleviates dysbiotic microbiota-induced intestinal graft-versus-host disease.

Autor: Hayase E; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Hayase T; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Mukherjee A; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Stinson SC; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Jamal MA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Ortega MR; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Sanchez CA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Ahmed SS; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Karmouch JL; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Chang CC; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Flores II; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., McDaniel LK; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Brown AN; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., El-Himri RK; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Chapa VA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Tan L; Metabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA., Tran BQ; Metabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA., Pham D; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Halsey TM; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Jin Y; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Tsai WB; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Prasad R; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Glover IK; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Ajami NJ; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Wargo JA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA., Shelburne S; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.; Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Okhuysen PC; Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Liu C; Department of Pathology, Yale School of Medicine, New Haven, Connecticut 06520, USA., Fowler SW; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Comparative Medicine, Baylor College of Medicine, Houston, TX 77030, USA., Conner ME; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA., Peterson CB; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Rondon G; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Molldrem JJ; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Champlin RE; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Shpall EJ; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Lorenzi PL; Metabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA., Mehta RS; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Martens EC; Department of Microbiology & Immunology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA., Alousi AM; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Jenq RR; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.; CPRIT Scholar in Cancer Research, Houston, Texas, USA.

Publikováno v: Research square [Res Sq] 2023 Jan 31. Date of Electronic Publication: 2023 Jan 31.