Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Chaozheng Zhou"'
Publikováno v:
Cancer Innovation, Vol 2, Iss 6, Pp 500-512 (2023)
Abstract Background Small‐cell lung cancer (SCLC) is characterized by its high malignancy and is associated with a poor prognosis. In the early stages of the disease, platinum‐based chemotherapy is the recommended first‐line treatment and has d
Externí odkaz:
https://doaj.org/article/bafbd824c23b4df4a65fb6fb256d97a6
Autor:
Zhifei Gao, Yifeng Bai, Anqi Lin, Aimin Jiang, Chaozheng Zhou, Quan Cheng, Zaoqu Liu, Xin Chen, Jian Zhang, Peng Luo
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-23 (2023)
Abstract As a nontraditional T-cell subgroup, γδT cells have gained popularity in the field of immunotherapy in recent years. They have extraordinary antitumor potential and prospects for clinical application. Immune checkpoint inhibitors (ICIs), w
Externí odkaz:
https://doaj.org/article/72076c932fd64fe0a514a23f9f837e88
Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
Autor:
Taojun Ye, Anqi Lin, Zhengang Qiu, Shulu Hu, Chaozheng Zhou, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107045- (2023)
Summary: There is an urgent need for markers to predict the efficacy of different chemotherapy drugs. Herein, we examined whether microsatellite instability (MSI) status can predict tumor multidrug sensitivity and explored the underlying mechanisms.
Externí odkaz:
https://doaj.org/article/df47a10b8ecb4920b175bfd5e7e0ee89
Autor:
Chaozheng Zhou, Shengkun Peng, Anqi Lin, Aimin Jiang, Yuanxi Peng, Tianqi Gu, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo
Publikováno v:
EClinicalMedicine, Vol 59, Iss , Pp 101967- (2023)
Summary: Background: With the increasing use of immune checkpoint inhibitors (ICIs) for tumour immunotherapy, the immune-related adverse events (irAEs) caused by their collateral effect on the immune system pose a key challenge for the clinical appli
Externí odkaz:
https://doaj.org/article/796f1a2dc68d4e7d8e1c506ca31a7ac6
Autor:
Jie Huang, PhD, Shi-Ling Zhang, BD, Chaozheng Zhou, BD, Weiye Huang, MD, Peng Luo, BD, Hua-Jun Chen, PhD, Jin-Ji Yang, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 6, Pp 100338- (2022)
Introduction: Neuroendocrine (NE) transformation has been reported in patients with ALK-rearranged NSCLC after ALK inhibition, but unlike EGFR-mutant NSCLC, the exact mechanism of NE transformation in ALK-rearranged NSCLC is poorly studied. Methods:
Externí odkaz:
https://doaj.org/article/0eb63644433047988664e378657e4873
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Genioplasty is the main way to treat diseases such as chin asymmetry, dysplasia and overdevelopment, which involve the three-dimensional direction abnormalities of the chin. Since this kind of surgery mainly uses intraoral incisions, the nar
Externí odkaz:
https://doaj.org/article/626c645bfea242b5bef648b7bb6b15ab
Autor:
Chaozheng Zhou, Anqi Lin, Manming Cao, Weimin Ding, Weiming Mou, Ningyi Guo, Zhenyu Chen, Jian Zhang, Peng Luo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immune checkpoint inhibitors (ICIs) have changed the treatment paradigm of metastatic urothelial carcinoma (mUC), a dominant type of bladder cancer (BC). Previous studies have shown an association between gene mutations in the DNA damage response (DD
Externí odkaz:
https://doaj.org/article/272500c79d814bc7aa797be92a69376f
Autor:
Weiyin Lin, Anqi Lin, Zhefu Li, Chaozheng Zhou, Chufeng Chen, Boliang Chen, Qingwen Lyu, Jian Zhang, Peng Luo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 131, Iss , Pp 110633- (2020)
Melanoma refers to a pigmented nevus with malignant changes. The preferred treatment for primary melanoma is surgical excision and postoperative radiotherapy, but the prognosis is poor. Immune checkpoint inhibitors (ICIs) have been remarkably success
Externí odkaz:
https://doaj.org/article/b525d204e7ff4bd2bac43abd3ad095dc
Multi-omics data plays an important role in cancer research, helping clinicians to better explore drug targets and biomarkers. At present, there exist several databases including TCGA (the Cancer Genome Atlas) and GDSC (Genomics of Drug Sensitivity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709d42e7092062524a2f3b590113aea8
https://doi.org/10.1101/2022.09.07.506938
https://doi.org/10.1101/2022.09.07.506938
Autor:
Tianqi Gu, Aimin Jiang, Chaozheng Zhou, Anqi Lin, Quan Cheng, Zaoqu Liu, Jian Zhang, Peng Luo
Publikováno v:
International journal of cancerREFERENCES. 152(3)
Immune checkpoint inhibitors (ICIs) combined with the anti-angiogenesis drug bevacizumab is one of the future directions of immunotherapy. However, the potential adverse drug reactions (ADRs) caused by combination therapy remain unclear. Current rese