Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chaozai Zhang"'
Autor:
Siyu Zhu, Chaozai Zhang, Lina S. Huang, Xing-Quan Zhang, Yan Xu, Xiong Fang, Jiao Zhou, Meixian Wu, Robert T. Schooley, Ziwei Huang, Jing An
Publikováno v:
Molecules, Vol 24, Iss 8, p 1465 (2019)
Zika virus (ZIKV), one of the flaviviruses, has attracted worldwide attention since its large epidemics around Brazil. Association of ZIKV infection with microcephaly and neurological problems such as Guillain–Barré syndrome has prompted intensive
Externí odkaz:
https://doaj.org/article/c02e3295e05c4768973eb72296069112
Autor:
Chaozai Zhang, Huijun Zhang, Lina S. Huang, Siyu Zhu, Yan Xu, Xing-Quan Zhang, Robert T. Schooley, Xiaohong Yang, Ziwei Huang, Jing An
Publikováno v:
Molecules, Vol 23, Iss 11, p 3036 (2018)
Human immunodeficiency virus type 1 (HIV-1) is responsible for the majority of HIV infections worldwide, and we still lack a cure for this infection. Blocking the interaction of HIV-1 and its primary receptor CD4 is one strategy for identifying new a
Externí odkaz:
https://doaj.org/article/4a308607a0484dd99f97f747e28c3c93
Publikováno v:
Exp Biol Med (Maywood)
The chemokine receptor CXCR4 is required for the entry of human immunodeficiency virus type 1 (HIV-1) into target cells and its expression correlates with more profound pathogenicity, rapid progression to acquired immunodeficiency syndrome (AIDS), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b571987ae8c04300542b60fc885c60
https://doi.org/10.1177/1535370220901498
https://doi.org/10.1177/1535370220901498
Autor:
Jing An, Huijun Zhang, Ziwei Huang, Chaozai Zhang, Xiaohong Yang, Siyu Zhu, Yan Xu, Jiao Zhou, Robert T. Schooley, Qian Meng, Xing-Quan Zhang, Lina S. Huang, Ruohan Zhu, Xiong Fang
Publikováno v:
Eur J Med Chem
G-protein coupled receptors (GPCRs) are implicated in many diseases and attractive targets for drug discovery. Peptide fragments derived from protein ligands of GPCRs are commonly used as probes of GPCR function and as leads for drug development. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40826fb1566e4d52505692b508ec707
https://escholarship.org/uc/item/3n594420
https://escholarship.org/uc/item/3n594420
Autor:
Jing An, Siyu Zhu, Boqiang Liang, Xiong Fang, Yan Xu, Lina S. Huang, Xing-Quan Zhang, Chaozai Zhang, Huijun Zhang, Qian Meng, Robert T. Schooley, Huang Ziwei, Juan Wang
Publikováno v:
European Journal of Medicinal Chemistry. 200:112410
CXCR4, a well-studied coreceptor of human immunodeficiency virus type 1 (HIV-1) entry, recognizes its cognate ligand SDF-1α (also named CXCL12) which plays many important roles, including regulating immune cells, controlling hematopoietic stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2dfa333340c97b7b5ce6a0ce0baca7
https://doi.org/10.1016/j.ejmech.2020.112410
https://doi.org/10.1016/j.ejmech.2020.112410
Autor:
Siyu Zhu, Robert T. Schooley, Jing An, Ziwei Huang, Xiaohong Yang, Lina S. Huang, Huijun Zhang, Xing-Quan Zhang, Chaozai Zhang, Yan Xu
Publikováno v:
Molecules (Basel, Switzerland), vol 23, iss 11
Molecules
Molecules, Vol 23, Iss 11, p 3036 (2018)
Volume 23
Issue 11
Molecules
Molecules, Vol 23, Iss 11, p 3036 (2018)
Volume 23
Issue 11
Human immunodeficiency virus type 1 (HIV-1) is responsible for the majority of HIV infections worldwide, and we still lack a cure for this infection. Blocking the interaction of HIV-1 and its primary receptor CD4 is one strategy for identifying new a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe682b838723b021a4c4e1a14d898de
https://escholarship.org/uc/item/91v3w803
https://escholarship.org/uc/item/91v3w803
Publikováno v:
J Clin Neurosci
Advances in therapies for breast cancer with cerebral metastases has been slow, despite this being a common diagnosis, due to limited drug delivery by the blood brain barrier. Improvements in drug delivery for brain metastasis to target the metastase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5858a27896224b6d3b9016bdafd1617
https://pubmed.ncbi.nlm.nih.gov/30678836
https://pubmed.ncbi.nlm.nih.gov/30678836
CXCR4 dimerization has been widely demonstrated both biologically and structurally. This paper mainly focused on the development of structure-based dimeric ligands that target SDF-1α-CXCR4 interaction and signaling. This study presents the design an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd453ac0ceee6283995d5cdb327be107
https://europepmc.org/articles/PMC5498155/
https://europepmc.org/articles/PMC5498155/