Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Chaoying Cui"'
Autor:
Min-Sheng Peng, Yan-Hu Liu, Quan-Kuan Shen, Xiao-Hua Zhang, Jiajia Dong, Jin-Xiu Li, Hui Zhao, Hui Zhang, Xiaoming Zhang, Yaoxi He, Hong Shi, Chaoying Cui, Ouzhuluobu, Tian-Yi Wu, Shi-Ming Liu, Gonggalanzi, Baimakangzhuo, Caijuan Bai, Duojizhuoma, Ti Liu, Shan-Shan Dai, Robert W. Murphy, Xue-Bin Qi, Guanghui Dong, Bing Su, Ya-Ping Zhang
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Domestication and introduction of dairy animals facilitated the permanent human occupation of the Tibetan Plateau. Yet the history of dairy pastoralism in the Tibetan Plateau remains poorly understood. Little is known how Tibetans
Externí odkaz:
https://doaj.org/article/93d0e9d40fcd442fb035a1cb85c806ee
Autor:
Wangshan Zheng, Yaoxi He, Yongbo Guo, Tian Yue, Hui Zhang, Jun Li, Bin Zhou, Xuerui Zeng, Liya Li, Bin Wang, Jingxin Cao, Li Chen, Chunxia Li, Hongyan Li, Chaoying Cui, Caijuan Bai, Baimakangzhuo, Xuebin Qi, Ouzhuluobu, Bing Su
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Background Tibetans are genetically adapted to high-altitude environments. Though many studies have been conducted, the genetic basis of the adaptation remains elusive due to the poor reproducibility for detecting selective signatures in the
Externí odkaz:
https://doaj.org/article/163b08b919484e2da7faba233901d414
Autor:
Yaoxi He, Wangshan Zheng, Yongbo Guo, Tian Yue, Chaoying Cui, Ouzhuluobu, Hui Zhang, Kai Liu, Zhaohui Yang, Tianyi Wu, Jia Qu, Zi-Bing Jin, Jian Yang, Fan Lu, Xuebin Qi, Bing Su
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107677- (2023)
Summary: Tibetans are the ideal population to study genetic adaptation in extreme environments. Here, we performed systematic phenotyping of 11,880 highlanders, covering 133 quantitative traits of 13 organ systems. We provided a comprehensive phenoty
Externí odkaz:
https://doaj.org/article/5cd7877ad75d47378e1d144baceb7e8a
Autor:
Jingxue Xin, Hui Zhang, Yaoxi He, Zhana Duren, Caijuan Bai, Lang Chen, Xin Luo, Dong-Sheng Yan, Chaoyu Zhang, Xiang Zhu, Qiuyue Yuan, Zhanying Feng, Chaoying Cui, Xuebin Qi, Ouzhuluobu, Wing Hung Wong, Yong Wang, Bing Su
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Tibetan adaptation to the high-altitude environment represents a case of natural selection during recent human evolution. Here the authors investigated the chromatin and transcriptional landscape of umbilical endothelial cells from Tibetan and Han Ch
Externí odkaz:
https://doaj.org/article/5d727e2e509d4204b777b2789c0541c6
HIF2A Variants Were Associated with Different Levels of High-Altitude Hypoxia among Native Tibetans.
Autor:
Zhuoma Basang, Boyang Wang, Lei Li, La Yang, Lan Liu, Chaoying Cui, Gongga Lanzi, Nima Yuzhen, Ji Duo, Hongxiang Zheng, Yi Wang, Shuhua Xu, Li Jin, Xiaofeng Wang
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137956 (2015)
Hypoxia inducible factors, including HIF1A and HIF2A, play central roles in response to high-altitude hypoxia and genetic variants of HIF1A or HIF2A were associated with high-altitude sickness or adaptation. However, it remains to determine whether t
Externí odkaz:
https://doaj.org/article/75a8d0942f624539835724f43db97374
Autor:
Zhaohui, Yang, Caijuan, Bai, Youwei, Pu, Qinghong, Kong, Yongbo, Guo, Xuyang, Liu, Qi, Zhao, Zhichao, Qiu, Wangshan, Zheng, Yaoxi, He, Yihan, Lin, Lian, Deng, Chao, Zhang, Shuhua, Xu, Yi, Peng, Kun, Xiang, Xiaoming, Zhang, Chaoying, Cui, Yongyue, Pan, Jingxue, Xin, Yong, Wang, Shiming, Liu, Liangbang, Wang, Hengliang, Guo, Zhenzhen, Feng, Shaobo, Wang, Hong, Shi, Binghua, Jiang, Tianyi, Wu, Xuebin, Qi, Bing, Su
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(40)
Strong ultraviolet (UV) radiation at high altitude imposes a serious selective pressure, which may induce skin pigmentation adaptation of indigenous populations. We conducted skin pigmentation phenotyping and genome-wide analysis of Tibetans in order
Autor:
Xin Luo, Jingxue Xin, Xuebin Qi, Zhanying Feng, Hui Zhang, Qiuyue Yuan, Wing Hung Wong, Yaoxi He, Lang Chen, Zhana Duren, Caijuan Bai, Yong Wang, Chaoyu Zhang, Ouzhuluobu, Dong Sheng Yan, Xiang Zhu, Chaoying Cui, Bing Su
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications
High-altitude adaptation of Tibetans represents a remarkable case of natural selection during recent human evolution. Previous genome-wide scans found many non-coding variants under selection, suggesting a pressing need to understand the functional r
Autor:
Yaoxi He, Jun Li, Tian Yue, Wangshan Zheng, Yongbo Guo, Hui Zhang, Li Chen, Chunxia Li, Hongyan Li, Chaoying Cui, null Ouzhuluobu, Xuebin Qi, Bing Su
Publikováno v:
Phenomics
Birth weight (BW) is a key determinant of infant mortality. Previous studies have reported seasonal fluctuation of BW. However, the responsible environmental factors remain disputable. High-altitude environment provides a great opportunity to test th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d238dcfb4b1659348b4a109c70a3d86
https://europepmc.org/articles/PMC9590487/
https://europepmc.org/articles/PMC9590487/
Autor:
Qing, Pan, Shun, Zha, Jingzhong, Li, Han, Guan, Jingjie, Xia, Jianhong, Yu, Chaoying, Cui, Yuanyuan, Liu, Jiayue, Xu, Jin, Liu, Gongbo, Chen, Min, Jiang, Juying, Zhang, Xianbin, Ding, Xing, Zhao
Publikováno v:
Science of The Total Environment. 834:155311
Wide pulse pressure (WPP) is a preclinical indicator for arterial stiffness and cardiovascular diseases. Long-term exposure to ambient particulate matters (PMs) would increase the risk of WPP. Although reducing pollutants emissions and avoiding outdo
Autor:
Xuebin Qi, Yongbo Guo, Bin Li, Zhilin Ning, Shuhua Xu, Yang Gao, Baimakangzhuo, Dejiquzong, Gonggalanzi, Xiaoji Wang, Shiming Liu, Tianyi Wu, Chaoying Cui, Ouzhuluobu, Wangshan Zheng, Lian Deng, Jun Li, Haiyi Lou, Duojizhuoma, Bing Su, Yaoxi He, Bianba, Caijuan Bai
Publikováno v:
National Science Review
Structural variants (SVs) may play important roles in human adaptation to extreme environments such as high altitude but have been under-investigated. Here, combining long-read sequencing with multiple scaffolding techniques, we assembled a high-qual