Zobrazeno 1 - 10 of 46 pro vyhledávání: '"Chaoxian Zhao"'
1
Akademický článek
Single-cell RNA-sequencing uncovers the dynamic changes of tumour immune microenvironment in advanced lung adenocarcinoma
Autor: Lei Cheng, Tianqing Chu, Haijiao Lu, Jialin Qian, Yinchen Shen, Chaoxian Zhao
Publikováno v: BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)
Background The heterogeneity of lung adenocarcinoma (LUAD) plays a vital role in determining the development of cancer and therapeutic sensitivity and significantly hinders the clinical treatment of LUAD.Objective To elucidate the cellular compositio
Externí odkaz: https://doaj.org/article/18f9224f03494d32b35710dd002a2421
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2
Akademický článek
CRNDE: A valuable long noncoding RNA for diagnosis and therapy of solid and hematological malignancies
Autor: Xuefei Ma, Wen Jin, Chaoxian Zhao, Xuefeng Wang, Kankan Wang
Publikováno v: Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 190-201 (2022)
Colorectal neoplasia differentially expressed (CRNDE) is an oncogenic long noncoding RNA (lncRNA). Increased CRNDE expression was initially discovered in colorectal cancer and then in a variety of solid tumors and hematological malignancies. CRNDE pa
Externí odkaz: https://doaj.org/article/2533fbb234cc40b09920fbc87831666d
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3
Akademický článek
Mitochondrial genomes of the early land plant lineage liverworts (Marchantiophyta): conserved genome structure, and ongoing low frequency recombination
Autor: Shanshan Dong, Chaoxian Zhao, Shouzhou Zhang, Li Zhang, Hong Wu, Huan Liu, Ruiliang Zhu, Yu Jia, Bernard Goffinet, Yang Liu
Publikováno v: BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background In contrast to the highly labile mitochondrial (mt) genomes of vascular plants, the architecture and composition of mt genomes within the main lineages of bryophytes appear stable and invariant. The available mt genomes of 18 live
Externí odkaz: https://doaj.org/article/d53b432f64ff4c55b556dad04c5f86ec
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4
Akademický článek
The complete mitochondrial genome of the early flowering plant Nymphaea colorata is highly repetitive with low recombination
Autor: Shanshan Dong, Chaoxian Zhao, Fei Chen, Yanhui Liu, Shouzhou Zhang, Hong Wu, Liangsheng Zhang, Yang Liu
Publikováno v: BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Mitochondrial genomes of flowering plants (angiosperms) are highly dynamic in genome structure. The mitogenome of the earliest angiosperm Amborella is remarkable in carrying rampant foreign DNAs, in contrast to Liriodendron, the o
Externí odkaz: https://doaj.org/article/96523adcf7a4496fb7b633977eb0db36
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5
ScRNA-seq revealed targeting regulator of G protein signaling 1 to mediate regulatory T cells in Hepatocellular carcinoma
Autor: Lianhong Zou, Kaihua Liu, Yongzhong Shi, Guowei Li, Haiyang Li, Chaoxian Zhao
Publikováno v: Cancer Biomarkers. 36:299-311
BACKGROUND: Regulatory T cells (Tregs) are central to determine immune response, thus targeting Tregs for immunotherapy is a promising strategy against tumor development and metastasis. OBJECTIVES: The objective of this study was to identify genes fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::640ce2e85554d7e05fccb726e17edd2b
https://doi.org/10.3233/cbm-220226
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6
A beneficial adaptive role for CHOP in driving cell fate selection during ER stress
Autor: Kaihua Liu, Chaoxian Zhao, D. Thomas Rutkowski
Publikováno v: bioRxiv
Cellular stresses elicit signaling cascades that are capable of both mitigating the inciting dysfunction and initiating cell death when the stress cannot be overcome. During endoplasmic reticulum (ER) stress, the transcription factor CHOP is widely r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6256b3ab826a9227c18227927aaa5e
https://europepmc.org/articles/PMC10055232/
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7
Ypel5 regulates liver development and function in zebrafish
Autor: Yun Deng, Xiao Han, Huiqiao Chen, Chaoxian Zhao, Yi Chen, Jun Zhou, Hugues de The, Jun Zhu, Hao Yuan
Publikováno v: Journal of Molecular Cell Biology.
YPEL5 is a member of the YPEL gene family that is evolutionarily conserved in the eukaryotic species. To date, the physiological function of YPEL5 has not been yet assessed due to a paucity of genetic animal models. Here, using CRISPR/Cas9-mediated g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6355ef611dd930d814778feb90e6f529
https://doi.org/10.1093/jmcb/mjad019
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10
Genetic Diversity, Heteroplasmy, and Recombination in Mitochondrial Genomes ofDaphnia pulex,Daphnia pulicaria, andDaphnia obtusa
Autor: Zhiqiang Ye, Chaoxian Zhao, R. Taylor Raborn, Man Lin, Wen Wei, Yue Hao, Michael Lynch
Publikováno v: Molecular Biology and Evolution. 39
Genetic variants of mitochondrial DNA at the individual (heteroplasmy) and population (polymorphism) levels provide insight into their roles in multiple cellular and evolutionary processes. However, owing to the paucity of genome-wide data at the wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40fa59fab8d8dc4491e512fdbc104a2a
https://doi.org/10.1093/molbev/msac059
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