Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Chaowei Shi"'
Autor:
Qilun Zhang, Xuting Shen, Xin Yuan, Jing Huang, Yaling Zhu, Tengteng Zhu, Tao Zhang, Haibo Wu, Qian Wu, Yinguang Fan, Jing Ni, Leilei Meng, Anyuan He, Chaowei Shi, Hao Li, Qingsong Hu, Jian Wang, Cheng Chang, Fan Huang, Fang Li, Meng Chen, Anding Liu, Shandong Ye, Mao Zheng, Haoshu Fang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Oxidative stress-induced lipid accumulation is mediated by lipid droplets (LDs) homeostasis, which sequester vulnerable unsaturated triglycerides into LDs to prevent further peroxidation. Here we identify the upregulation of lipopolysacchari
Externí odkaz:
https://doaj.org/article/cd628ea85d2a4584a3d193cdf6fe7360
Autor:
Yongjin Wang, Yang Zhou, Chaowei Shi, Jiacong Liu, Guohua Lv, Huisi Huang, Shengrong Li, Liping Duan, Xinyi Zheng, Yue Liu, Haibo Zhou, Yonghua Wang, Zhengqiu Li, Ke Ding, Pinghua Sun, Yun Huang, Xiaoyun Lu, Zhi-Min Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Antimicrobial toxins are secreted by bacteria to kill rival species. Here the authors report the mechanism of inhibition of EsaD, a toxin secreted by some S. aureus strains to kill competitors that lack the antitoxin EsaG, showing marked mechanistic
Externí odkaz:
https://doaj.org/article/39d230a9e5b34ce1a16578c05946a891
Autor:
Fucsia Crea, Antreas Vorkas, Aoife Redlich, Rubén Cruz, Chaowei Shi, Dirk Trauner, Adam Lange, Ramona Schlesinger, Joachim Heberle
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Optogenetics in the conventional sense, i.e. the use of engineered proteins that gain their light sensitivity from naturally abundant chromophores, represents an exciting means to trigger and control biological activity by light. As an alternate appr
Externí odkaz:
https://doaj.org/article/252058baea61487ba4001928c8af6fab
Autor:
Chaowei Shi, Yao He, Kitty Hendriks, Bert L. de Groot, Xiaoying Cai, Changlin Tian, Adam Lange, Han Sun
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
NaK is a non-selective cation channel that conducts sodium (Na+) and potassium (K+) equally well. Here authors use ssNMR and MD simulations to show that the selectivity filter of NaK adopts two conformations in the absence of ions, one of which is pr
Externí odkaz:
https://doaj.org/article/0e20ab2b76714568a57a0701df6d9902
Publikováno v:
Chinese Chemical Letters. 33:747-750
Current resolved structures of GPCRs and G protein complexes provided important insights into G protein activation. However, the binding or dissociation of GPCRs with G protein is instantaneous and highly dynamic in the intracellular environment. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a70d38feaf4f1ea9cfc76e3fe556d3a5
https://doi.org/10.1016/j.cclet.2021.07.042
https://doi.org/10.1016/j.cclet.2021.07.042
Autor:
Wei-Wei Shi, Chaowei Shi, Tong-Yue Wang, Yu-Lei Li, Yong-Kang Zhou, Xu-Han Zhang, Donald Bierer, Ji-Shen Zheng, Lei Liu
Publikováno v:
Journal of the American Chemical Society. 144:349-357
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::737bcbbdeb3f2b8c67539fb3fcdb15bf
https://doi.org/10.1021/jacs.1c10091
https://doi.org/10.1021/jacs.1c10091
Autor:
Rui Zhao, Pan Shi, Ji‐bin Cui, Chaowei Shi, Xiao‐Xiong Wei, Jie Luo, Zhemin Xia, Wei‐Wei Shi, Yingxin Zhou, Jiahui Tang, Changlin Tian, Mark Meininghaus, Donald Bierer, Jing Shi, Yi‐Ming Li, Lei Liu
Publikováno v:
Angewandte Chemie. 135
Chemical synthesis of insulin superfamily proteins (ISPs) has recently been widely studied to develop next-generation drugs. Separate synthesis of multiple peptide fragments and tedious chain-to-chain folding are usually encountered in these studies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c614a9886f4038319a0a153e84698c
https://doi.org/10.1002/ange.202216365
https://doi.org/10.1002/ange.202216365
Autor:
Dan Song, Lisha Kuang, Lin Yang, Lei Wang, Hao Li, Xiu Li, Zhimin Zhu, Chaowei Shi, Haining Zhu, Weimin Gong
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Stress granules (SGs) are cytoplasmic biomolecular condensates containing proteins and RNAs in response to stress. Ras-GTPase–activating protein binding protein 1 (G3BP1) is a core SG protein. Caprin-1 and ubiquitin specific peptidase 10 (USP10) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c85f431c11b49818e7310a2638f7cba
https://doi.org/10.1073/pnas.2207975119
https://doi.org/10.1073/pnas.2207975119
Autor:
Demeng Sun, Xianyu Meng, Shenghai Chang, Chaowei Shi, Shenglong Ling, Sanling Liu, Longhua Zhang, Xing Zhang, Pan Shi, Yingxin Zhou, Wenjing Sun, Lei Liu, Changlin Tian
Publikováno v:
Cell Research. 31:383-394
The human calcium-sensing receptor (CaSR) is a class C G protein-coupled receptor (GPCR) responsible for maintaining Ca2+ homeostasis in the blood. The general consensus is that extracellular Ca2+ is the principal agonist of CaSR. Aliphatic and aroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fb2870ef0936d7bf696d57919528633
https://doi.org/10.1038/s41422-021-00474-0
https://doi.org/10.1038/s41422-021-00474-0
Autor:
Adam Lange, Tillmann Utesch, Susanne Bischoff, Chaowei Shi, Claudia Bohg, Sascha Lange, Han Sun, Carl Öster
Publikováno v:
Chemical Science
Intramembrane proteolysis plays a fundamental role in many biological and pathological processes. Intramembrane proteases thus represent promising pharmacological targets, but few selective inhibitors have been identified. This is in contrast to thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56bed5965b92fbccd67fa177032a842
https://doi.org/10.1039/d1sc02146j
https://doi.org/10.1039/d1sc02146j