Výsledky vyhledávání - "Chaopeng Xiong"

Akademický článek

Alpha linolenic acid intake alleviates myocardial ischemia/reperfusion injury via the P2X7R/NF-κB signalling pathway

Autor: Shuo Wang, Chaxian Liu, Chengxin Gong, Tao Li, Jiani Zhao, Wen Xiao, Yuanyuan Liu, Shanping Peng, Chaopeng Xiong, Rumeng Wang, Lu Ding, Xingzi Liu, Shangdong Liang, Hong Xu

Publikováno v: Journal of Functional Foods, Vol 49, Iss , Pp 1-11 (2018)

This study investigated the protective role of α-linolenic acid (ALA) in myocardial ischemia/reperfusion (MI/R) injury. ALA was indicated to dose-dependently protect myocardium against I/R injury, attenuate purinergic P2X7 receptor (P2X7R) activatio

Externí odkaz: https://doaj.org/article/e153ece4fded4e03a9cf9db33c2623bf

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Association ofP2X7Rgene with serum lipid profiles in Chinese postmenopausal women with osteoporosis

Autor: Xingzi Liu, Dan Luo, Tao Li, Wen Xiao, Chaopeng Xiong, Shanping Peng, Jiani Zhao, Hong Xu, C Gong, Shangdong Liang, Yuanyuan Liu, Rumeng Wang

Publikováno v: Climacteric. 22:498-506

Objectives: The aim was to study the relationship between purinergic P2X7 receptor (P2X7R) functional genetic polymorphisms and lipid profiles in Chinese postmenopausal osteoporosis (OP) pa...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3166a2d0a5e855706a0d0d7b7fe9f02d
https://doi.org/10.1080/13697137.2019.1604654

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Noncoding transcribed ultraconserved region (T‐UCR) UC.48+ is a novel regulator of high‐fat diet induced myocardial ischemia/reperfusion injury

Autor: Jiani Zhao, Lu Ding, Rumeng Wang, Shenqiang Rao, Tao Li, Shuo Wang, Shanping Peng, Wen Xiao, Xingzi Liu, Hong Xu, Yuanyuan Liu, Chengxin Gong, Shangdong Liang, Chaopeng Xiong

Publikováno v: Journal of Cellular Physiology. 234:9849-9861

Increasing evidence has suggested high-fat diet (HFD) is an independent risk factor for myocardial ischemia/reperfusion (MI/R) injury. Long noncoding RNAs (lncRNAs) recently attracted much attraction in the study of MI/R injury. However, the function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d34953c47bc60826cb252d2e345b15
https://doi.org/10.1002/jcp.27674

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Purinergic P2X7 receptor functional genetic polymorphisms are associated with the susceptibility to osteoporosis in Chinese postmenopausal women

Autor: Luling He, Yongfang Fan, Fangfang Hu, Peipei Zhong, Yuping Yang, Tao Li, Shangdong Liang, Changle Liu, Xingzi Liu, Shuo Wang, Lan Tang, Hong Xu, Shenqiang Rao, Lu Ding, Chaopeng Xiong, Yijun Nie, Yunming Tu, Chengxin Gong, Hui Wang

Publikováno v: Purinergic Signalling. 13:339-346

Osteoporosis (OP) is a major public health problem worldwide. Genetic factors are considered to be major contributors to the pathogenesis of OP. The purinergic P2X7 receptor (P2X7R) has been shown to play a role in the regulation of osteoblast and os

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b232d6c7f76a2f6faf877133d39f98a1
https://doi.org/10.1007/s11302-017-9566-3

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A high concentration of fatty acids induces TNF-α as well as NO release mediated by the P2X4 receptor, and the protective effects of puerarin in RAW264.7 cells

Autor: Fangfang Hu, Shangdong Liang, Lu Ding, Tao Li, Xingzi Liu, Shuo Wang, Yunming Tu, Chengxin Gong, Chaopeng Xiong, Hong Xu

Publikováno v: Food & Function. 8:4336-4346

Circulating levels of free fatty acids (FFAs) are often found to be increased in patients with type 2 diabetes mellitus (T2DM) and metabolic syndrome (MS). High plasma FFA levels may give rise to maladaptive macrophage activation and promote inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5fa67d9e6497710fff21758cb3c0c5
https://doi.org/10.1039/c7fo00544j

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Functional mechanisms for diabetic nephropathy-associated genetic variants

Autor: Wen Xiao, Shangdong Liang, Changle Liu, Mei Yang, Lu Ding, Mengqi Xiong, Yongfang Fan, Chaopeng Xiong, Shenqiang Rao, Luling He, Yonghu Xu, Fangfang Hu, Lan Tang, Hong Xu, Chengxin Gong, Xingzi Liu

Publikováno v: Genes & Genomics. 38:595-600

Diabetic nephropathy (DN) is one of the major complications of diabetes. A tremendous amount of genetic variations have been identified to be associated with DN. However, most of them only generate from statistical associations at the DNA level, gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1881352892c762d4eb72b3b8a711794d
https://doi.org/10.1007/s13258-016-0415-5

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A non-synonymous polymorphism in purinergic P2X7 receptor gene confers reduced susceptibility to essential hypertension in Chinese postmenopausal women

Autor: Shuo Wang, Yuping Yang, Chengxin Gong, Shenqiang Rao, Yuanyuan Liu, Jiani Zhao, Hong Xu, Chaxian Liu, Shangdong Liang, Tao Li, Chaopeng Xiong, Lu Ding, Xingzi Liu

Publikováno v: Clinical and experimental hypertension (New York, N.Y. : 1993). 41(6)

Essential hypertension (EH), characterized by elevated blood pressure (systolic blood pressure, SBP ≥ 140 mmHg and/or diastolic blood pressure, DBP ≥ 90 mmHg), has become a major public health conc...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b319190309c68986ba62e97c37c8ec
https://pubmed.ncbi.nlm.nih.gov/30359160

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Purinergic P2X7 receptor functional genetic polymorphisms are associated with the susceptibility to obesity in Chinese postmenopausal women

Autor: Lu Ding, Tao Li, Hong Xu, Shuo Wang, Yunming Tu, Xingzi Liu, Jiani Zhao, Peipei Zhong, Chaopeng Xiong, Shangdong Liang, Shenqiang Rao, Jihong Wang, Chengxin Gong, Yuru Zhou

Publikováno v: Menopause (New York, N.Y.). 25(3)

OBJECTIVE We conducted a case-control study to investigate the associations of functional single-nucleotide polymorphisms in the purinergic P2X7 receptor (P2X7R) gene (rs2393799, rs7958311, rs1718119, rs2230911, and rs3751143) with obesity and overwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccc461fa48e704d13a4bc82d61b86c2
https://pubmed.ncbi.nlm.nih.gov/29088017

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Genetic interaction of purinergic P2X7 receptor and ER-α polymorphisms in susceptibility to osteoporosis in Chinese postmenopausal women

Autor: Yunming Tu, Jihong Wang, Jiani Zhao, Yuping Yang, Tao Li, Shangdong Liang, Shuo Wang, Xingzi Liu, Hong Xu, Chengxin Gong, Yuru Zhou, Shenqiang Rao, Peipei Zhong, Yansong Xue, Chaopeng Xiong, Hui Wang, Luling He, Lu Ding, Yijun Nie

Publikováno v: Journal of bone and mineral metabolism. 36(4)

Osteoporosis (OP) is an increasing public health problem worldwide. Genetic factors are considered to be major contributors to the pathogenesis of OP. The aim of this study was to investigate the association of the purinergic P2X7 receptor (P2X7R) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1099db0cc3477a947d2664f5cb117e44
https://pubmed.ncbi.nlm.nih.gov/28884379

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