Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chaomei Lin"'
Publikováno v:
Journal of Biological Chemistry. 274:9648-9655
We previously raised an antibody (RA6.3) by an antiidiotypic approach which was designed to be directed against an amiloride binding domain on the epithelial Na+ channel (ENaC). This antibody mimicked amiloride in that it inhibited transepithelial Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd2817aba9c8d0d79f7d8b9e5402900
https://doi.org/10.1074/jbc.274.14.9648
https://doi.org/10.1074/jbc.274.14.9648
Autor:
Chaomei Lin, Catherine M. Fuller, Roger T. Worrell, Douglas C. Eaton, Holly K. Patton, Vadim Shlyonsky, Weijing Sun, Bakhram K. Berdiev, Jonathan B. Zuckerman, Thomas R. Kleyman, Dale J. Benos, Iskander I. Ismailov, Thomas Kieber-Emmons
Publikováno v:
Journal of Biological Chemistry. 272:21075-21083
Limited information is available regarding domains within the epithelial Na+ channel (ENaC) which participate in amiloride binding. We previously utilized the anti-amiloride antibody (BA7.1) as a surrogate amiloride receptor to delineate amino acid r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::016783dac92e498460e211ce1fe6537c
https://doi.org/10.1074/jbc.272.34.21075
https://doi.org/10.1074/jbc.272.34.21075
Autor:
Farhad Kosari, Thomas R. Kleyman, Chaomei Lin, Thomas Kieber-Emmons, Katherine V. Prammer, Annabelle Villalobos
Publikováno v:
Kidney International. 48:956-964
Defining topological similarities among ion transport proteins with anti-amiloride antibodies. The structural features of amiloride binding sites on amiloride-sensitive transport proteins have received limited characterization. An antibody that recog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650790c5f898cac519029efa59fa9667
https://doi.org/10.1038/ki.1995.377
https://doi.org/10.1038/ki.1995.377
Publikováno v:
Journal of Pharmacy and Pharmacology. 43:200-203
Rats were implanted subcutaneously with osmotic mini-pumps containing either 0.9% NaCl, nicotine (1.5 or 4.5 mg kg−1 day−1), or cocaine (30 mg kg−1 day−1), for 14 days. Neither nicotine nor cocaine treatment significantly altered the maximal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43877f34915d85af77ea99f01c300d8a
https://doi.org/10.1111/j.2042-7158.1991.tb06666.x
https://doi.org/10.1111/j.2042-7158.1991.tb06666.x
Publikováno v:
American journal of physiology. Renal physiology. 285(6)
One of the defining characteristics of the epithelial sodium channel (ENaC) is its block by the diuretic amiloride. This study investigates the role of the extracellular loop of the α-subunit of ENaC in amiloride binding and stabilization. Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308cbdc4550f9f59ac6e2cd0c1074474
https://pubmed.ncbi.nlm.nih.gov/12928313
https://pubmed.ncbi.nlm.nih.gov/12928313
Publikováno v:
The American journal of physiology. 267(3 Pt 1)
Amiloride and related compounds have found widespread use as cation transport inhibitors. We have previously raised a series of polyclonal anti-amiloride antibodies using different amiloride-protein conjugates as immunogens, where amiloride was coupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221922ef44439e6f67577f0f371075a2
https://pubmed.ncbi.nlm.nih.gov/7524337
https://pubmed.ncbi.nlm.nih.gov/7524337
Publikováno v:
Analytical biochemistry. 198(1)
125I-containing compounds that react specifically with sulfhydryl groups were prepared in yields of 30 to 40% on the basis of starting 125I quantity. The synthetic precursors were commercially available heterobifunctional crosslinkers and the peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f13b859111f02a0c73a5325b7720de7
https://pubmed.ncbi.nlm.nih.gov/1789420
https://pubmed.ncbi.nlm.nih.gov/1789420
Publikováno v:
Biochemical pharmacology. 41(5)
The antagonist potency of a series of bivalent adrenocorticotropic hormone (ACTH) peptides was examined using suspensions of inner zone rat adrenocortical cells. Bivalent antagonists were prepared by bis(maleimide) covalent cross-linking of carboxyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbc7a9472ff5ba259a43938200e4847
https://pubmed.ncbi.nlm.nih.gov/1847814
https://pubmed.ncbi.nlm.nih.gov/1847814
Publikováno v:
Biochimica et biophysica acta. 1038(3)
A two-step procedure for introduction of sulfhydryl groups at protein carboxyl groups is described. The resultant proteins contain 2-aminoethanethiol residues bound by amide linkages to the protein carboxyl groups. First an amide bond is formed betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ce222ed863fa520b821e7dd68a0341
https://pubmed.ncbi.nlm.nih.gov/2160279
https://pubmed.ncbi.nlm.nih.gov/2160279
Publikováno v:
American Journal of Physiology: Cell Physiology; Sep1994, Vol. 267 Issue 3, pC821-C826, 6p