Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Chaolie Huang"'
Autor:
Chaolie Huang, Sara Wagner-Valladolid, Amberley D Stephens, Raimund Jung, Chetan Poudel, Tessa Sinnige, Marie C Lechler, Nicole Schlörit, Meng Lu, Romain F Laine, Claire H Michel, Michele Vendruscolo, Clemens F Kaminski, Gabriele S Kaminski Schierle, Della C David
Publikováno v:
eLife, Vol 8 (2019)
Reduced protein homeostasis leading to increased protein instability is a common molecular feature of aging, but it remains unclear whether this is a cause or consequence of the aging process. In neurodegenerative diseases and other amyloidoses, spec
Externí odkaz:
https://doaj.org/article/d304ea99735c4d8ea67842213713ac7f
Autor:
Nicole Groh, Anika Bühler, Chaolie Huang, Ka Wan Li, Pim van Nierop, August B. Smit, Marcus Fändrich, Frank Baumann, Della C. David
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Aging is the most important risk factor for neurodegenerative diseases associated with pathological protein aggregation such as Alzheimer’s disease. Although aging is an important player, it remains unknown which molecular changes are relevant for
Externí odkaz:
https://doaj.org/article/6922cd6cd3ef43cca1c2695e5e6e5d1e
Autor:
Raimund Jung, Waltraud Röseler, Sinem Agilkaya, Ivan Gallotta, Martin Haslbeck, Ralf J. Sommer, Della C. David, Christian Rödelsperger, Chaolie Huang, Jane L. Blersch, Aneet Sandhu, Maximilian Peters
Publikováno v:
Nature / Physical science 584(7821), 410-414 (2020). doi:10.1038/s41586-020-2461-z
In metazoans, the secreted proteome participates in intercellular signalling and innate immunity, and builds the extracellular matrix scaffold around cells. Compared with the relatively constant intracellular environment, conditions for proteins in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7551d1df24598615d1d5f8f956f7e582
Autor:
Marie C. Lechler, Claire H. Michel, G. S. Kaminski Schierle, Chaolie Huang, Raimund Jung, Chetan Poudel, Clemens F. Kaminski, Della C. David, N. Schlörit, A.D. Stephens, Michele Vendruscolo, Romain F. Laine, Tessa Sinnige, Sara Wagner-Valladolid
Reduced protein homeostasis and increased protein instability is a common feature of aging. Yet it remains unclear whether protein instability is a cause of aging. In neurodegenerative diseases and amyloidoses, specific proteins self-assemble into am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd3f0aaba92d0d8b1562dd9e98d11e31
Publikováno v:
Journal of Visualized Experiments.
In the last decades, the prevalence of neurodegenerative disorders, such as Alzheimer's disease (AD) and Parkinson's disease (PD), has grown. These age-associated disorders are characterized by the appearance of protein aggregates with fibrillary str
Autor:
Nicole, Groh, Ivan, Gallotta, Marie C, Lechler, Chaolie, Huang, Raimund, Jung, Della C, David
Publikováno v:
JoVE journal Biology(129), 56464 (2017). doi:10.3791/56464
In the last decades, the prevalence of neurodegenerative disorders, such as Alzheimer's disease (AD) and Parkinson's disease (PD), has grown. These age-associated disorders are characterized by the appearance of protein aggregates with fibrillary str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8f9331a1fe485b30cbb1aa6fa5233d53
Publikováno v:
genesis. 52:120-126
Summary Protocadherins represent the biggest subgroup within the cadherin superfamily of transmembrane glycoproteins. In contrast to classical type I cadherins, protocadherins in general exhibit only moderate adhesive activity. During embryogenesis,
Publikováno v:
Developmental biology. 411(2)
The cranial neural crest (CNC) is a highly motile and multipotent embryonic cell population, which migrates directionally on defined routes throughout the embryo, contributing to facial structures including cartilage, bone and ganglia. Cadherin-media
Autor:
Dimitar R. Stamov, Doris Wedlich, Jubin Kashef, Chaolie Huang, Clemens M. Franz, Sarah F. S. Becker, Carina Gonnermann
Publikováno v:
Integrative biology, 7 (3), 356-363
AFM-based force spectroscopy in combination with optical microscopy is a powerful tool for investigating cell mechanics and adhesion on the single cell level. However, standard setups featuring an AFM mounted on an inverted light microscope only prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310bf4e284375295721a6e4b912b51d7
Publikováno v:
Genesis (New York, N.Y. : 2000). 52(2)
Protocadherins represent the biggest subgroup within the cadherin superfamily of transmembrane glycoproteins. In contrast to classical type I cadherins, protocadherins in general exhibit only moderate adhesive activity. During embryogenesis, they are