Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Chaokui Wang"'
Autor:
Jianping Hu, Chaokui Wang, Xinyue Huang, Shenglan Yi, Su Pan, Yiting Zhang, Gangxiang Yuan, Qingfeng Cao, Xingsheng Ye, Hong Li
Publikováno v:
Cell Reports, Vol 36, Iss 12, Pp 109726- (2021)
Summary: Gut microbiota-mediated secondary bile acids (BAs) play an important role in energy balance and host metabolism via G protein-coupled receptors and/or nuclear receptors. Emerging evidence suggests that BAs are important for maintaining innat
Externí odkaz:
https://doaj.org/article/ad8b7ca2443745b4b7fbe453a5cad4ec
Autor:
Jianping Hu, Shenglan Yi, Chaokui Wang, Yiting Zhang, Jihong Tang, Xinyue Huang, Lu Yang, Jinglu Yang, Hong Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
A20 is a negative regulator of inflammation and immunity and plays a role in several autoimmune and inflammatory diseases. Here, we demonstrate that A20 overexpression significantly ameliorates severity of EAU by inhibiting the infiltration of Th1 an
Externí odkaz:
https://doaj.org/article/3b180fa18ec14175baa47be563ee313f
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
High-salt has been shown to play a role in the pathogenesis of autoimmune disease. In this study, we investigated the effect of high-salt on the production of inflammatory mediators by ARPE-19 cells and the possible mechanisms involved. ARPE-19 cells
Externí odkaz:
https://doaj.org/article/4cd81839eee148e0854e42945e905dbe
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Recent studies show that the aryl hydrocarbon receptor (AhR) is involved in immune responses. AhR is activated following interaction with its ligands, such as 6-formylindolo[3,2-b]carbazole (FICZ) and 2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxy
Externí odkaz:
https://doaj.org/article/20fd55f8ae754f1197a95a6cd81cacb9
Autor:
Tao Cai, Qian Wang, Qingyun Zhou, Chaokui Wang, Shengping Hou, Jian Qi, Aize Kijlstra, Peizeng Yang
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59009 (2013)
OBJECTIVE: Interleukin (IL)-22 has been reported to be involved in the development of autoimmune diseases. This study aimed to analyze the expression and potential role of IL-22 in the pathogenesis of Behcet's disease (BD). METHODS: The levels of IL-
Externí odkaz:
https://doaj.org/article/886014a02d834e2386478fe33bea270f
Autor:
Lichun Tian, Peizeng Yang, Bo Lei, Ju Shao, Chaokui Wang, Qin Xiang, Lin Wei, Zhougui Peng, Aize Kijlstra
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19542 (2011)
BackgroundRecent reports show that gene therapy may provide a long-term, safe and effective intervention for human diseases. In this study, we investigated the effectiveness of adeno-associated virus 2 (AAV2) based human interferon-alpha (hIFN-α) ge
Externí odkaz:
https://doaj.org/article/aa02fc6b890a4c099b44e472ad781bbc
Autor:
Gangxiang Yuan, Wanyun Zhang, Yan Ji, Yizong Liu, Su Pan, Yujing Li, Xiao Tan, Zhangluxi Liu, Rui Chang, Jiadong Ding, Jing Xu, Zhenyu Zhong, Nobuhisa Mizuki, Wenjuan Zhuang, Guannan Su, Weiting Liao, Jia Shu, Jing Shi, Akira Meguro, Masaki Takeuchi, Fuzhen Li, Xiaojie Feng, Liping Du, Meifen Zhang, Handan Tan, Jun Zhang, Liang Liang, Shigeaki Ohno, Yuqin Wang, Aize Kijlstra, Xingsheng Ye, Qingyun Zhou, Tingting Pang, Hongxi Li, Shiyao Tan, Yingnan Gao, Zi Ye, Chaokui Wang, Ying Zhu, Wei Chi, Zhijun Chen, Ling Chen, Qingfeng Wang, Xianbo Zuo, Shenglan Yi, Peizeng Yang, Qingfeng Cao, Fanfan Huang, Xiaoli Liu
Publikováno v:
Arthritis & Rheumatology, 74(4):41998, 671-681. Wiley
OBJECTIVE: To explore susceptibility loci associated with uveitis in Behçet's disease (BD).METHODS: We conducted a 2-stage study, consisting of a genome-wide association study (GWAS) stage and a replication stage, in a Chinese population. The GWAS s
Autor:
Jianping Hu, Yiting Zhang, Shenglan Yi, Chaokui Wang, Xinyue Huang, Su Pan, Jinglu Yang, Gangxiang Yuan, Sisi Tan, Hong Li
Publikováno v:
International Journal of Biological Sciences. 18:4545-4559
Dendritic cells (DCs) are the major antigen-presenting cells and play an important role in autoimmune uveitis. Emerging evidence suggests that bile acids (BAs) regulate DCs maturation. However, the underlying mechanisms by which BAs regulate the func
Autor:
Xiaoxiao Cui, Gangxiang Yuan, Xiao Tan, Peizeng Yang, Guannan Su, Aize Kijlstra, Qingfeng Cao, Ying Zhu, Chaokui Wang, Liming Zhang, Yang Huang, Wenjun Zhou
Publikováno v:
Inflammation, 43(5), 1780-1788. Springer
Previous studies have pointed out that indoleamine 2,3-dioxygenase (IDO), the rate-limiting enzyme initiating tryptophan metabolism, plays a role in the regulation of the immune system. This project was designed to investigate the potential role of I
Publikováno v:
J Cell Commun Signal
Retinoblastoma (RB) is one of the most common ophthalmic tumors, and most of the patients have been identified as advanced at the time of diagnosis, which is directly related to high mortality. Recent studies showed that long noncoding RNA (lncRNA) a