Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Chaojian Wang"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0301293 (2024)
Bicycle safety has emerged as a pressing concern within the vulnerable transportation community. Numerous studies have been conducted to identify the significant factors that contribute to the severity of cyclist injuries, yet the findings have been
Externí odkaz:
https://doaj.org/article/0e9fc0f368944a38aab3830933b81305
Autor:
Beilei Lei, Chaojian Wang, Kamie Snow, Murilo E. Graton, Robert M. Tighe, Ammon M. Fager, Maureane R. Hoffman, Paloma H. Giangrande, Francis J. Miller, Jr.
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 662-673 (2023)
Acute lung injury (ALI) is a syndrome of acute inflammation, barrier disruption, and hypoxemic respiratory failure associated with high morbidity and mortality. Diverse conditions lead to ALI, including inhalation of toxic substances, aspiration of g
Externí odkaz:
https://doaj.org/article/60455e7ecf584a589b079e930bb50ded
Publikováno v:
Journal of Advanced Transportation, Vol 2023 (2023)
Two-wheeled (TW) vehicle accidents are one of the major types of urban traffic accidents. TW cyclists who lack safety protection usually suffer more serious injuries and deaths in collisions. Developments in automotive active safety technologies are
Externí odkaz:
https://doaj.org/article/b4f554956af84a1baa9e22464ed74bda
Autor:
Hengtao Zhang, Victoria Graham Bryson, Chaojian Wang, TianYu Li, Jaclyn P. Kerr, Rebecca Wilson, Deborah M. Muoio, Robert J. Bloch, Christopher Ward, Paul B. Rosenberg
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility
Externí odkaz:
https://doaj.org/article/4ef5dfde9ee943f784bb8eee0d805e3a
Autor:
Jeffrey Abrams, Daniel Roybal, Nourdine Chakouri, Alexander N. Katchman, Richard Weinberg, Lin Yang, Bi-xing Chen, Sergey I. Zakharov, Jessica A. Hennessey, Uma Mahesh R. Avula, Johanna Diaz, Chaojian Wang, Elaine Y. Wan, Geoffrey S. Pitt, Manu Ben-Johny, Steven O. Marx
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
The Ca2+-binding protein calmodulin has emerged as a pivotal player in tuning Na+ channel function, although its impact in vivo remains to be resolved. Here, we identify the role of calmodulin and the NaV1.5 interactome in regulating late Na+ current
Externí odkaz:
https://doaj.org/article/efe44da0f05e4c1a960d684f11a8834d
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152355 (2016)
Drug-induced long-QT syndrome (diLQTS) is often due to drug block of IKr, especially in genetically susceptible patients with subclinical mutations in the IKr-encoding KCHN2. Few variants in the cardiac NaV1.5 Na+ channel complex have been associated
Externí odkaz:
https://doaj.org/article/980314b680cc4cab97dff3df5131dd03
Publikováno v:
BioTechniques, Vol 36, Iss 6, Pp 1010-1016 (2004)
Avidin was covalently linked to aldehyde-derivatized polyethersulfone membrane filters. These filters were used in Western blot analysis of proteins reacted with biotinylation reagents and electrophoresed in sodium dodecyl sulfate (SDS) on polyacryla
Externí odkaz:
https://doaj.org/article/bacaa8456bfb4b41b4ab47405aa903cf
Publikováno v:
eLife, Vol 3 (2014)
Rapid firing of cerebellar Purkinje neurons is facilitated in part by a voltage-gated Na+ (NaV) ‘resurgent’ current, which allows renewed Na+ influx during membrane repolarization. Resurgent current results from unbinding of a blocking particle t
Externí odkaz:
https://doaj.org/article/cbaad12c755a48169192b7e5c3aad79a
Autor:
Victoria Bryson, Chaojian Wang, Zirui Zhou, Kavisha Singh, Noah Volin, Eda Yildirim, Paul Rosenberg
Publikováno v:
bioRxiv
Stromal interaction molecule 1 (STIM1) is a Ca2+sensor located in the sarcoplasmic reticulum (SR) of skeletal muscle where it is best known for its role in store operated Ca2+entry (SOCE). Genetic syndromes resulting from STIM1 mutations are recogniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e375846a6bb8f3536371aa9806a55317
https://doi.org/10.1101/2023.05.03.539279
https://doi.org/10.1101/2023.05.03.539279
Publikováno v:
Pflugers Archiv
Store-operated Ca2+ entry (SOCE) is an ancient and ubiquitous Ca2+ signaling pathway that is present in virtually every cell type. Over the last two decades, many studies have implicated this non-voltage dependent Ca2+ entry pathway in cardiac physio