Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Chaohuan Guo"'
Autor:
Yimei Lai, Siyuan Zhao, Binfeng Chen, Yuefang Huang, Chaohuan Guo, Mengyuan Li, Baokui Ye, Shuyi Wang, Hui Zhang, Niansheng Yang
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Abstract Background T helper cells in patients with autoimmune disease of idiopathic inflammatory myopathies (IIM) are characterized with the proinflammatory phenotypes. The underlying mechanisms remain unknown. Methods RNA sequencing was performed f
Externí odkaz:
https://doaj.org/article/308ff26d523447ac94dd2428c2023940
Autor:
Tengyue Zhang, Mengyuan Li, Siyuan Zhao, Mianjing Zhou, Huai Liao, Haiyan Wu, Xinyue Mo, Hongxing Wang, Chaohuan Guo, Hui Zhang, Niansheng Yang, Yuefang Huang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundType II alveolar epithelial cell (AEC II), in addition to its roles in maintaining lung homeostasis, takes an active role in inflammatory response during acute lung injury (ALI). Ca2+/calmodulin-dependent protein kinase IV (CaMK4) activated
Externí odkaz:
https://doaj.org/article/7d6b9e155d65450fb9b469ae4edf0735
Autor:
Xue Li, Qin Zeng, Shuyi Wang, Mengyuan Li, Xionghui Chen, Yuefang Huang, Binfeng Chen, Mianjing Zhou, Yimei Lai, Chaohuan Guo, Siyuan Zhao, Hui Zhang, Niansheng Yang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Store-operated Ca2+ release-activated Ca2+ (CRAC) channel is the main Ca2+ influx pathway in lymphocytes and is essential for immune response. Lupus nephritis (LN) is an autoimmune disease characterized by the production of autoantibodies due to wide
Externí odkaz:
https://doaj.org/article/6dca18f57eb3462fb00b2f184afa21c2
Autor:
Mengyuan Li, Yimei Lai, Binfeng Chen, Chaohuan Guo, Mianjing Zhou, Siyuan Zhao, Shuyi Wang, Jin Li, Niansheng Yang, Hui Zhang
Publikováno v:
Molecular Therapy. 31:193-210
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bae8f9f69f095c8b05bba388068d770
https://doi.org/10.1016/j.ymthe.2022.09.013
https://doi.org/10.1016/j.ymthe.2022.09.013
Publikováno v:
Clinical and Experimental Nephrology. 26:1055-1066
Focal segmental glomerulosclerosis (FSGS) is characterized by podocyte damage and severe proteinuria. The exact mechanism of podocyte damage and loss remains unclear. Necroptosis, a lytic form of programmed cell death mediated by RIP3 and MLKL, has e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ea61bbc548fa67dbbb496cf1e8b044
https://doi.org/10.1007/s10157-022-02258-1
https://doi.org/10.1007/s10157-022-02258-1
Autor:
Mianjing, Zhou, Mengyuan, Li, Chaohuan, Guo, Shuang, Wang, Xue, Li, Siyuan, Zhao, Hui, Zhang, Niansheng, Yang
Publikováno v:
Clinical and Experimental Rheumatology. 39:804-810
Idiopathic inflammatory myopathies (IIM) are a group of disorders characterised by the production of autoantibodies and inflammatory infiltrates in the skeletal muscles. Follicular T helper (TFH) cells are known to be crucial for B cell differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ba3d5defe291934655351afe6a9bd7
https://doi.org/10.55563/clinexprheumatol/gfqlcz
https://doi.org/10.55563/clinexprheumatol/gfqlcz
Autor:
Qin Zeng, Shuyi Wang, Mengyuan Li, Shuang Wang, Chaohuan Guo, Xinyuan Ruan, Ryu Watanabe, Yimei Lai, Yuefang Huang, Xiaoyu Yin, Chuanzhao Zhang, Binfeng Chen, Niansheng Yang, Hui Zhang
Publikováno v:
Cell Metabolism. 35:837-854.e8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04d14a73afedc7a27f22fb57e236debd
https://doi.org/10.1016/j.cmet.2023.03.010
https://doi.org/10.1016/j.cmet.2023.03.010
Autor:
Zhenhuan Zhao, Bihua Xu, Shuang Wang, Mianjing Zhou, Yuefang Huang, Chaohuan Guo, Mengyuan Li, Jijun Zhao, Sun-Sang J Sung, Felicia Gaskin, Niansheng Yang, Shu Man Fu
Publikováno v:
Ann Rheum Dis
ObjectiveNLRP3 inflammasome regulates T cell responses. This study examined the roles of NLRP3 inflammasome activation in the regulation of T follicular helper (Tfh) cells during humoral response to T dependent antigens and in systemic lupus erythema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c7a2aefe73dc7a828656fd1d87ae84
https://europepmc.org/articles/PMC9262832/
https://europepmc.org/articles/PMC9262832/
Autor:
Mengyuan, Li, Yimei, Lai, Binfeng, Chen, Chaohuan, Guo, Mianjing, Zhou, Siyuan, Zhao, Shuyi, Wang, Jin, Li, Niansheng, Yang, Hui, Zhang
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy.
Interferon γ (IFNγ) produced by T cells represents the featured cytokine and is central to the pathogenesis of lupus nephritis (LN). Here, we identified nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in the salvage NAD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4310ad597c38b348bde0c6ba8059b2ba
https://pubmed.ncbi.nlm.nih.gov/36146932
https://pubmed.ncbi.nlm.nih.gov/36146932
Autor:
Meiling Liu, Chaohuan Guo, Jijun Zhao, Mianjing Zhou, Meirong Li, Hechang Tan, Niansheng Yang, Yong Xia, Rong Fu, Shuang Wang, Renxiang Mao
Publikováno v:
Arthritis & Rheumatology. 71:1308-1318
OBJECTIVE Lupus nephritis (LN) is a major determinant of morbidity and mortality in systemic lupus erythematosus (SLE). Pim-1 regulates lymphocyte proliferation and activation. The role of Pim-1 in autoimmune disease remains unclear. This study was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e266c551751ebc9eba3c151fcc39bf5f
https://doi.org/10.1002/art.40863
https://doi.org/10.1002/art.40863