Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Chaohan, Xu"'
Autor:
Yingli Lv, Guotao Feng, Lei Yang, Xiaoliang Wu, Chengyi Wang, Aokun Ye, Shuyuan wang, Chaohan Xu, Hongbo Shi
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28586- (2024)
Whole genome doublings (WGD), a hallmark of human cancer, is pervasive in breast cancer patients. However, the molecular mechanism of the complete impact of WGD on survival and treatment response in breast cancer remains unclear. To address this, we
Externí odkaz:
https://doaj.org/article/a6c380d2e6d54942b215fcdcf24d5141
Publikováno v:
BMC Plant Biology, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Seed dormancy and germination are key components of plant regeneration strategies. Aconitum barbatum is a plant commonly found in northeast China. Although it has potential for use in gardening and landscaping, its seed dormancy a
Externí odkaz:
https://doaj.org/article/68d314156c384a61a82958fb945c7333
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveFinding target genes and target pathways of existing drugs for drug repositioning in multiple sclerosis (MS) based on transcriptomic changes in MS immune cells.Materials and MethodsBased on transcriptome data from Gene Expression Omnibus (GE
Externí odkaz:
https://doaj.org/article/52b310335a5e4872a175c9eafe6d0618
Publikováno v:
Agronomy, Vol 13, Iss 5, p 1250 (2023)
The timing of seed germination significantly affects the fitness and life cycle of plants. Torilis scabra is a perennial medicinal herb occurring in mixed forests but the increasing use and modification of forestlands in recent decades has led to the
Externí odkaz:
https://doaj.org/article/e6e2f40cc9cf412ab8d99aaa1a945d07
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 464-479 (2020)
Somatic copy-number alterations (SCNAs) drive tumor growth and evolution. However, the functional roles of SCNAs across the genome are still poorly understood. We provide an integrative strategy to characterize the functional roles of driver SCNAs in
Externí odkaz:
https://doaj.org/article/51653b64538b472eaccad67860713379
Autor:
Kaiyuan Xing, Bo Zhang, Zixuan Wang, Yanru Zhang, Tengyue Chai, Jingkai Geng, Xuexue Qin, Xi Steven Chen, Xinxin Zhang, Chaohan Xu
Publikováno v:
Cells, Vol 12, Iss 3, p 367 (2023)
Triple-negative breast cancer (TNBC) is a highly heterogeneous disease with different molecular subtypes. Although progress has been made, the identification of TNBC subtype-associated biomarkers is still hindered by traditional RNA-seq or array tech
Externí odkaz:
https://doaj.org/article/ed51672a522643ea8abfcb47156551d3
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Single-cell RNA sequencing (scRNA-seq) is a high-throughput sequencing technology performed at the level of an individual cell, which can have a potential to understand cellular heterogeneity. However, scRNA-seq data are high-dimensional, noisy, and
Externí odkaz:
https://doaj.org/article/4c0fab8de2eb4274a91e8aca0a3dcfd2
Autor:
Shuyuan Wang, Wencan Wang, Weida Wang, Peng Xia, Lei Yu, Ye Lu, Xiaowen Chen, Chaohan Xu, Hui Liu
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Breast cancer (BC) is one of the most common tumors, leading the causes of cancer death in women. However, the pathogenesis of BC still remains unclear, and the atlas of BC-associated risk factors is far from complete. In this study, we constructed a
Externí odkaz:
https://doaj.org/article/c558d7ee071f47488139d2ccf1cc3f3d
Autor:
Yanyan Ping, Chaohan Xu, Liwen Xu, Gaoming Liao, Yao Zhou, Chunyu Deng, Yujia Lan, Fulong Yu, Jian Shi, Li Wang, Yun Xiao, Xia Li
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Engineered organoids by sequential introduction of key mutations could help modeling the dynamic cancer progression. However, it remains difficult to determine gene paths which were sufficient to capture cancer behaviors and to broadly explain cancer
Externí odkaz:
https://doaj.org/article/1911b664630a470baa6e9fa27ad508ad
Autor:
Jinyuan Xu, Xiaobo Hou, Lin Pang, Shangqin Sun, Shengyuan He, Yiran Yang, Kun Liu, Linfu Xu, Wenkang Yin, Chaohan Xu, Yun Xiao
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Gliomas represent 80% of malignant brain tumors. Because of the high heterogeneity, the oncogenic mechanisms in gliomas are still unclear. In this study, we developed a new approach to identify dysregulated competitive endogenous RNA (ceRNA) interact
Externí odkaz:
https://doaj.org/article/60aa732cde1247a4bf304034384fe533