Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Chaofang Jin"'
Autor:
John C. Reed, Arnold C. Satterthwait, Shinichi Kitada, Chung-wai Shiau, Chaofang Jin, Dayong Zhai
The natural product gambogic acid (GA) has been reported to have cytotoxic activity against tumor cells in culture and was identified as an active compound in a cell-based high-throughput screening assay for activators of caspases, proteases involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019014f3c61dec3e54e036602714c7b1
https://doi.org/10.1158/1535-7163.c.6531768.v1
https://doi.org/10.1158/1535-7163.c.6531768.v1
Autor:
John C. Reed, Arnold C. Satterthwait, Shinichi Kitada, Chung-wai Shiau, Chaofang Jin, Dayong Zhai
Supplementary Fig. from Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f7fb38f99676adc48bb0e87b761a5f
https://doi.org/10.1158/1535-7163.22485087
https://doi.org/10.1158/1535-7163.22485087
Autor:
John C. Reed, Chaofang Jin, Eric Chi-Wang Yu, Guy S. Salvesen, Dayong Y. Zhai, Robert C. Liddington, Chung-wei Shiau, Kate Welsh, Lili Chen
Publikováno v:
Journal of Biological Chemistry. 285:5569-5580
Apoptosis plays important roles in host defense, including the elimination of virus-infected cells. The executioners of apoptosis are caspase family proteases. We report that vaccinia virus-encoded F1L protein, previously recognized as anti-apoptotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534ac106d5793323fdac2c585bc49f89
https://doi.org/10.1074/jbc.m109.078113
https://doi.org/10.1074/jbc.m109.078113
Autor:
Dayong Zhai, Robert C. Liddington, Chaofang Jin, Boguslaw Stec, Mika Aoyagi, Alexander E. Aleshin, John C. Reed
Publikováno v:
Protein Science. 16:118-124
Poxviruses encode immuno-modulatory proteins capable of subverting host defenses. The poxvirus vaccinia expresses a small 14-kDa protein, N1L, that is critical for virulence. We report the crystal structure of N1L, which reveals an unexpected but str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ea2113d0e96abda89502ef02bc97c8e
https://doi.org/10.1110/ps.062454707
https://doi.org/10.1110/ps.062454707
Autor:
Eduard Sergienko, John C. Reed, Paul Diaz, P.H.C. Godoi, Dayong Zhai, Brock Brown, Xochella Chan, Chaofang Jin, Russell Dahl, Ying Su, Justin Rascon, Thomas D.Y. Chung, Andrew Hurder
Publikováno v:
Journal of biomolecular screening. 17(3)
Overexpression of the anti-apoptotic Bcl-2 family proteins occurs commonly in human cancers. Bfl-1 is highly expressed in some types of malignant cells, contributing significantly to tumor cell survival and chemoresistance. Therefore, it would be des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11a1cc8f79e54b683b30485515cd535
https://pubmed.ncbi.nlm.nih.gov/22156224
https://pubmed.ncbi.nlm.nih.gov/22156224
Autor:
Motti Gerlic, John C. Reed, Chaofang Jin, Eric Chi-Wang Yu, Dayong Zhai, Robert C. Liddington
In multicellular organisms, apoptosis is a powerful method of host defense against viral infection. Apoptosis is mediated by a cascade of caspase-family proteases that commit infected cells to a form of programmed cell death. Therefore, to replicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c09febea29a53eb81be3564cc8804e
https://europepmc.org/articles/PMC3162436/
https://europepmc.org/articles/PMC3162436/
Autor:
Chung Wai Shiau, Shinichi Kitada, Dayong Zhai, Chaofang Jin, John C. Reed, Arnold C. Satterthwait
The natural product gambogic acid (GA) has been reported to have cytotoxic activity against tumor cells in culture and was identified as an active compound in a cell-based high-throughput screening assay for activators of caspases, proteases involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca6da2df38bb5d0142de570c36544ee
https://europepmc.org/articles/PMC2614397/
https://europepmc.org/articles/PMC2614397/
Publikováno v:
The Journal of biological chemistry. 283(15)
The pro-apoptotic members of the Bcl-2 family include initiator proteins that contain only BH3 domains and downstream effector multi-BH domain-containing proteins, including Bax and Bak. In this report, we compared the ability of the six human anti-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1af8fd27b1d099761b0c216f09c0e3b
https://pubmed.ncbi.nlm.nih.gov/18178565
https://pubmed.ncbi.nlm.nih.gov/18178565
Autor:
Dayong Zhai1, Chaofang Jin1, Ziwei Huang1, Satterthwait, Arnold C.1, Reed, John C.1 reedoffice@burnham.org
Publikováno v:
Journal of Biological Chemistry. 4/11/2008, Vol. 283 Issue 15, p9580-9586. 7p. 1 Chart, 6 Graphs.
Autor:
Dayong Zhai1, Yu, Eric1, Chaofang Jin1, Welsh, Kate1, Chung-wei Shiau1, Lili Chen1, Salvesen, Guy S.1, Liddington, Robert1, Reed, John C.1 reedoffice@sanford-burnham.org
Publikováno v:
Journal of Biological Chemistry. 2/19/2010, Vol. 285 Issue 8, p5569-5580. 12p.