Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Chaochao Ge"'
Autor:
Senzhen Wang, Xiaojuan Xu, Delu Che, Ronghui Fan, Mengke Gao, Yue Cao, Chaochao Ge, Yongli Feng, Jinghua Li, Songqiang Xie, Chaojie Wang, Fujun Dai, Lei Gao, Yuxia Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 10987 (2021)
Increasing the level of reactive oxygen species (ROS) in cancer cells has been suggested as a viable approach to cancer therapy. Our previous study has demonstrated that mitochondria-targeted flavone-naphthalimide-polyamine conjugate 6c elevates the
Externí odkaz:
https://doaj.org/article/1b8b7b788e7a459f9b9fa9f327cd26aa
Autor:
Lei Gao, Chaochao Ge, Senzhen Wang, Xiaojuan Xu, Yongli Feng, Xinna Li, Chaojie Wang, Yuxia Wang, Fujun Dai, Songqiang Xie
Publikováno v:
Cancers, Vol 12, Iss 3, p 528 (2020)
Colorectal cancer (CRC) is one of the most prevalent cancers due to its frequency and high rate of mortality. Polyamine-vectorized anticancer drugs possess multiple biological properties. Of these drugs, 9F has been shown to inhibit tumor growth and
Externí odkaz:
https://doaj.org/article/9c74574c78ce458a85d23e6df61cb041
Autor:
Chaochao Ge, Liping Chang, Ying Zhao, Congcong Chang, Xiaojuan Xu, Haoying He, Yuxia Wang, Fujun Dai, Songqiang Xie, Chaojie Wang
Publikováno v:
Molecules, Vol 22, Iss 2, p 342 (2017)
Two kinds of naphthalimide derivatives were synthesized and evaluated for in vitro their anti-hepatocellular carcinoma properties. Compound 3a with a fused thiazole fragment to naphthalimide skeleton inhibited cell migration of SMMC-7721 and HepG2, a
Externí odkaz:
https://doaj.org/article/6e9f52eb35d2483f878b45ec06666016
Autor:
Fujun Dai, Chaojie Wang, Yuxia Wang, Yuan Zhao, Songqiang Xie, Zhiyang Zhang, Lei Gao, Chaochao Ge, Kemeng Zhang, Yanming Wang, Yongli Feng, Xiaojuan Xu, Senzhen Wang
Publikováno v:
Cancer Letters. 519:30-45
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide. Oxidative phosphorylation (OXPHOS) has attracted a considerable attention in CRC. It is of great interest to explore novel therapies that inhibit OXPHOS for CRC treatment. Compou
Autor:
Xiaojuan Xu, Yuxia Wang, Songqiang Xie, Xinna Li, Yongli Feng, Chaochao Ge, Lei Gao, Senzhen Wang, Fujun Dai, Chaojie Wang
Publikováno v:
Cancers, Vol 12, Iss 3, p 528 (2020)
Cancers; Volume 12; Issue 3; Pages: 528
Cancers
Cancers; Volume 12; Issue 3; Pages: 528
Cancers
Colorectal cancer (CRC) is one of the most prevalent cancers due to its frequency and high rate of mortality. Polyamine-vectorized anticancer drugs possess multiple biological properties. Of these drugs, 9F has been shown to inhibit tumor growth and
Autor:
Chaojie Wang, Chaochao Ge, Songqiang Xie, Kemeng Zhang, Fujun Dai, Xiaojuan Xu, Lei Gao, Xinna Li, Yongli Feng, Senzhen Wang
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 85
Background Colorectal cancer (CRC) is one of the most common malignancies worldwide. Metastasis is the major cause of death in patients with CRC. Lycorine, the phenanthridine alkaloid most commonly found in spp of the Amaryllidaceae family, has shown
Autor:
Liu Xiaodan, Shuai Chen, Yuxia Wang, Runguo Tian, Songqiang Xie, Ying Chen, Wen Luo, Jinghua Li, Chaojie Wang, Fujun Dai, Chaochao Ge, Senzhen Wang, Ya-Cheng Yang
Publikováno v:
Journal of Medicinal Chemistry. 61:6814-6829
Polyamine derivatives have a promising prospect in dealing with disseminated tumor cells, a major obstacle in cancer therapy. To develop a bifunctional polyamine derivative that can serve as a fluorescent probe and an antimetastatic agent, three kind
Autor:
Zhiyong Tian, Meng Li, Fujun Dai, Yuxia Wang, Senzhen Wang, Songqiang Xie, Chaojie Wang, Chaochao Ge, Liping Chang, Luyao Zhao
Publikováno v:
European Journal of Medicinal Chemistry. 143:1732-1743
A new class of polyamine analogues modified by alkylation at the terminal of the polyamine chain has been synthesized and their structures were determined by 1H NMR, 13C NMR, ESI-MS and elemental analysis. As the representative compound, 3f displayed
Autor:
Delu Che, Songqiang Xie, Ronghui Fan, Senzhen Wang, Yuxia Wang, Lei Gao, Mengke Gao, Yongli Feng, Fujun Dai, Chaojie Wang, Xiaojuan Xu, Chaochao Ge, Yue Cao, Jinghua Li
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10987, p 10987 (2021)
Volume 22
Issue 20
International Journal of Molecular Sciences, Vol 22, Iss 10987, p 10987 (2021)
Increasing the level of reactive oxygen species (ROS) in cancer cells has been suggested as a viable approach to cancer therapy. Our previous study has demonstrated that mitochondria-targeted flavone-naphthalimide-polyamine conjugate 6c elevates the
Autor:
Qian Li, Haoying He, Songqiang Xie, Chaochao Ge, Chaojie Wang, Yuxia Wang, Chenyang Feng, Xiaojuan Xu, Fujun Dai
Publikováno v:
Journal of Medicinal Chemistry. 60:2071-2083
Approximately 90% of cancer-associated deaths result from disseminated tumors, indicating the ineffectiveness of current therapies and the imperative need of antimetastatic drugs. A novel pharmacophore with flavonoid and naphthalimide moieties was co