Zobrazeno 1 - 10
of 18
pro vyhledávání: '"ChaoYu Jin"'
Autor:
Richard T. George, Liron Abuhatzira, Susan M. Stoughton, Sotirios K. Karathanasis, Dewei She, ChaoYu Jin, Nicholas A. P. S. Buss, Rebecca Bakker‐Arkema, Emily L. Ongstad, Michael Koren, Boaz Hirshberg
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 13 (2021)
Background MEDI6012 is recombinant human lecithin cholesterol acyltransferase, the rate‐limiting enzyme in reverse cholesterol transport. Infusions of lecithin cholesterol acyltransferase have the potential to enhance reverse cholesterol transport
Externí odkaz:
https://doaj.org/article/1a70f3f882f34faebeab6817f3357b2e
Autor:
Michael J. Koren, ChaoYu Jin, Rebecca Bakker-Arkema, Liron Abuhatzira, Dewei She, Boaz Hirshberg, Richard T George, Emily L. Ongstad, Nicholas A P S Buss, Susan M Stoughton, Sotirios K. Karathanasis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background MEDI6012 is recombinant human lecithin cholesterol acyltransferase, the rate‐limiting enzyme in reverse cholesterol transport. Infusions of lecithin cholesterol acyltransferase have the potential to enhance reverse cholesterol transport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ba2d209839d960299a3b3593e85a51
https://doi.org/10.1161/jaha.119.014572
https://doi.org/10.1161/jaha.119.014572
Autor:
Judith Hsia, Chang Yeop Han, Bill Cook, Minal B. Mehta, Tomas Vaisar, Melissa Damschroder, ChaoYu Jin, Alan Chait, Holly Kimko, Lan-Feng Tsai, Glenn Carlson, Qun Du, David Han, Boaz Hirshberg, B. Timothy Hummer, Nicholas Bhagroo, Judith Falloon, Anton I. Rosenbaum, Joseph Grimsby, Steven Novick, Sotirios K. Karathanasis, John E. Le Lay, Christopher J. Rhodes
Publikováno v:
Science Translational Medicine. 13
Cardiovascular disease (CVD) is the leading global cause of death, and treatments that further reduce CV risk remain an unmet medical need. Epidemiological studies have consistently identified low high-density lipoprotein cholesterol (HDL-C) as an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b806a69f8bbce11f56c6f79f662b55
https://doi.org/10.1126/scitranslmed.abb0602
https://doi.org/10.1126/scitranslmed.abb0602
Autor:
George, Richard T., Abuhatzira, Liron, Stoughton, Susan M., Karathanasis, Sotirios K., Dewei She, ChaoYu Jin, Buss, Nicholas A. P. S., Bakker-Arkema, Rebecca, Ongstad, Emily L., Koren, Michael, Hirshberg, Boaz, She, Dewei, Jin, ChaoYu
Publikováno v:
Journal of the American Heart Association; 7/6/2021, Vol. 10 Issue 13, p1-15, 31p
Autor:
Richard T George, Liron Abuhatzira, David A. Morrow, Boaz Hirshberg, Andrea L Vavere, Sotirios K. Karathanasis, Marc P. Bonaca, Dewei She, Brian A. Bergmark, Jeong-Gun Park, Judy Hsia, ChaoYu Jin, Marc S. Sabatine
Publikováno v:
European heart journal. Cardiovascular pharmacotherapy. 8(3)
Aims Reverse cholesterol transport (RCT) removes cholesterol and stabilizes vulnerable plaques. In addition, high-density lipoprotein (HDL) may be cardioprotective in acute myocardial infarction (MI). Lecithin-cholesterol acyltransferase (LCAT) may e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696fc37362fd85807675f4e36562ee7f
https://pubmed.ncbi.nlm.nih.gov/33493256
https://pubmed.ncbi.nlm.nih.gov/33493256
Autor:
Rajesh Narwal, Brandon W. Higgs, Yanan Zheng, Bing Wang, Ashok Kumar Gupta, Xiaoping Jin, Pralay Mukhopadhyay, Chaoyu Jin, Paul Baverel, Lorin Roskos, Yong Ben
Publikováno v:
Clinical Pharmacology and Therapeutics
Durvalumab is an anti-PD-L1 monoclonal antibody approved for patients with locally advanced or metastatic urothelial carcinoma (UC) that has progressed after platinum-containing chemotherapy. A population tumor kinetic model, coupled with dropout and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4d17b86e4490356f61970422e9141b
https://doi.org/10.1002/cpt.986
https://doi.org/10.1002/cpt.986
Autor:
Mark P. Chao, Roy Louis Maute, Chris H. Takimoto, ChaoYu Jin, Balaji Agoram, David A. Sallman
Publikováno v:
Journal of Clinical Oncology. 38:e15098-e15098
e15098 Background: Magrolimab (Hu5F9-G4) is a monoclonal IgG4 antibody that binds to CD47 receptor and blocks its interaction with SIRPA, thereby enabling tumor cell phagocytosis and activation of an anti-tumor T-cell response. Magrolimab has shown e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7811f00830b13ba3868e5a69fe24e8dd
https://doi.org/10.1200/jco.2020.38.15_suppl.e15098
https://doi.org/10.1200/jco.2020.38.15_suppl.e15098
Autor:
Yanan Zheng, Pralay Mukhopadhyay, Rajesh Narwal, Chaoyu Jin, Brandon W. Higgs, Paul Baverel, Ashok K. Gupta, Lorin Roskos
Publikováno v:
Annals of Oncology. 29:viii423
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f124362ac332cc5de660af8d8ec9c751
https://doi.org/10.1093/annonc/mdy288.061
https://doi.org/10.1093/annonc/mdy288.061
Autor:
Vincent Dubois, Lorin Roskos, Ashok Kumar Gupta, Xuyang Song, Xiaoping Jin, Chaoyu Jin, Rajesh Narwal, Pralay Mukhopadhyay, Paul Baverel, Phillip A. Dennis, Yong Ben
Publikováno v:
Journal of Clinical Oncology. 35:2566-2566
2566 Background: Durvalumab is a human monoclonal antibody that binds to PD-L1 and blocks its interaction with PD-1 and CD80. The objectives of this analysis were to develop a population pharmacokinetics (PK) model of durvalumab, to quantitate the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79621a7a589eb480fe464c7f1b13c369
https://doi.org/10.1200/jco.2017.35.15_suppl.2566
https://doi.org/10.1200/jco.2017.35.15_suppl.2566
Autor:
Pralay Mukhopadhyay, Lorin Roskos, Phillip A. Dennis, Chaoyu Jin, Brandon W. Higgs, Ashok Kumar Gupta, Yanan Zheng, Bing Wang, Xiaoping Jin, Rajesh Narwal
Publikováno v:
Journal of Clinical Oncology. 35:11555-11555
11555 Background: Durvalumab is a human monoclonal antibody that binds to PD-L1 and blocks its interaction with PD-1 and CD80. The primary objectives of this analysis were to describe the longitudinal tumor size profiles and identify the key factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fdfec925d5b7133b3643f5ee2841f64
https://doi.org/10.1200/jco.2017.35.15_suppl.11555
https://doi.org/10.1200/jco.2017.35.15_suppl.11555