Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Chao-Zhong Song"'
Autor:
Mingdong Liu, Chao Zhong Song, Patrick A. Navas, David W. Emery, George Stamatoyannopoulos, Hao Wang, Matthew T. Maurano, John A. Stamatoyannopoulos, Heyuan Qi
Publikováno v:
Nature Biotechnology. 33:198-203
Insertional mutagenesis and genotoxicity, which usually manifest as hematopoietic malignancy, represent major barriers to realizing the promise of gene therapy. Although insulator sequences that block transcriptional enhancers could mitigate or elimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3ee893807db1dcc74fb2a2dd7ad643
https://doi.org/10.1038/nbt.3062
https://doi.org/10.1038/nbt.3062
Publikováno v:
Journal of Molecular Biology. 366:1064-1073
Sp/KLF family of factors regulates gene expression by binding to the CACCC/GC/GT boxes in the DNA through their highly conserved three zinc finger domains. To investigate the role of this family of factors in erythroid differentiation and globin gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5346275676df0405d4513f262069c676
https://doi.org/10.1016/j.jmb.2006.12.047
https://doi.org/10.1016/j.jmb.2006.12.047
Publikováno v:
Journal of Molecular Biology. 329:207-215
The transcriptional co-activators CBP/p300 and PCAF participate in transcriptional activation by many factors. We have shown that both CBP/p300 and PCAF stimulate the transcriptional activation by KLF13, a member of the KLF/Sp1 family, either individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c285ca9817cc8e2688d3e8b913525cd
https://doi.org/10.1016/s0022-2836(03)00429-7
https://doi.org/10.1016/s0022-2836(03)00429-7
Publikováno v:
Biochemical and Biophysical Research Communications. 296:118-124
CBP and p300 are transcriptional coactivators that physically interact with diverse sequence-specific DNA-binding factors through conserved domains. To further investigate the functional roles of these protein-interaction domains in CBP/p300 regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63339a3a85a0f912fe88c4032f1d54c
https://doi.org/10.1016/s0006-291x(02)00842-2
https://doi.org/10.1016/s0006-291x(02)00842-2
Publikováno v:
Journal of Biological Chemistry. 277:7029-7036
The Sp1/KLF family of factors regulates diverse cellular processes, including growth and development. Fetal Krüppel-like factor (FKLF2) is a new member of this family. In this study, we characterized the coactivators involved in FKLF2 transcriptiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176890015f04609d70428beff666fac6
https://doi.org/10.1074/jbc.m108826200
https://doi.org/10.1074/jbc.m108826200
Autor:
Chao-Zhong Song, Maurice Green, Paul M. Loewenstein, Karoly Toth, Qing-quan Tang, A Nishikawa
Publikováno v:
Molecular and Cellular Biology. 17:2186-2193
The human adenovirus E1A 243 amino acid oncoprotein possesses a transcription repression function that appears to be linked with its ability to induce cell cycle progression and to inhibit cell differentiation. The molecular mechanism of E1A repressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dbf9cf5aa4f53445a6878903f0619a
https://doi.org/10.1128/mcb.17.4.2186
https://doi.org/10.1128/mcb.17.4.2186
Autor:
Y. Eugene Chen, Jiandie D. Lin, Yanbo Fan, Malayannan Subramaniam, Milton H. Hamblin, Jifeng Zhang, Chao Zhong Song, Siming Li, John R. Hawse, Tainqing Zhu, Ke-Jie Yin, Raul Urrutia
Publikováno v:
Brain : a journal of neurology. 136(Pt 4)
Peroxisome proliferator-activated receptor gamma (PPARγ) is emerging as a major regulator in neurological diseases. However, the role of (PPARγ) and its co-regulators in cerebrovascular endothelial dysfunction after stroke is unclear. Here, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aeaa6e3476874b711726a6791d9d8be
https://pubmed.ncbi.nlm.nih.gov/23408111
https://pubmed.ncbi.nlm.nih.gov/23408111
Publikováno v:
Proceedings of the National Academy of Sciences. 92:10330-10333
The 243-amino acid adenovirus E1A oncoprotein both positively and negatively modulates the expression of cellular genes involved in the regulation of cell growth. The E1A transcription repression function appears to be linked with its ability to indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93d5f1da8666eab225c8699bc80b7d7
https://doi.org/10.1073/pnas.92.22.10330
https://doi.org/10.1073/pnas.92.22.10330
Autor:
Stanley T. Bayley, Chao-Zhong Song, Janey Symington, Paul M. Loewenstein, Maurice Green, Rozalia Pusztai, Karoly Toth, Akira Nishikawa, Christopher J. Tierney, Qing-quan Tang
Publikováno v:
Journal of Biological Chemistry. 270:23263-23267
The human adenovirus E1A 243R protein (243 residues) transcriptionally represses a set of cellular genes that regulate cellular growth and differentiation. We describe two lines of evidence that E1A repression does not require cellular protein synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8ba01c3fae1bcd3303e092a7247166
https://doi.org/10.1074/jbc.270.40.23263
https://doi.org/10.1074/jbc.270.40.23263
Publikováno v:
Journal of Virology. 69:2907-2911
Human adenovirus E1A proteins can repress the expression of several viral and cellular genes. By using a cell-free transcription system, we demonstrated that the gene product of the E1A 12S mRNA, the 243-residue protein E1A243R, inhibits basal transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0b62b2136c44aceb0f149e67496975
https://doi.org/10.1128/jvi.69.5.2907-2911.1995
https://doi.org/10.1128/jvi.69.5.2907-2911.1995