Zobrazeno 1 - 10
of 445
pro vyhledávání: '"Chao-Wen Cheng"'
Autor:
Chih-Chieh Chang, Yoko K. Takada, Chao-Wen Cheng, Yukina Maekawa, Seiji Mori, Yoshikazu Takada
Publikováno v:
Cells, Vol 13, Iss 4, p 307 (2024)
FGF9 is a potent mitogen and survival factor, but FGF9 protein levels are generally low and restricted to a few adult organs. Aberrant expression of FGF9 usually results in cancer. However, the mechanism of FGF9 action has not been fully established.
Externí odkaz:
https://doaj.org/article/614fb72014324302bdc8aa35442eed17
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1435 (2023)
During tumorigenesis, urokinase (uPA) and uPA receptor (uPAR) play essential roles in mediating pathological progression in many cancers. To understand the crosstalk between the uPA/uPAR signaling and cancer, as well as to decipher their cellular pat
Externí odkaz:
https://doaj.org/article/5ef1403f0385457fa28b441a5916c190
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/9fa4533892e6408aabc829c253acf11b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract A link between sex hormones and B-cell activating factor (BAFF), a crucial immunoregulator of autoimmune thyroid disease (AITD), may exist. The study aimed to elucidate the role of estrogen (E2) in regulating BAFF in Graves' disease (GD). In
Externí odkaz:
https://doaj.org/article/fb9203b171414f159c482ee2b8acc310
Publikováno v:
Archives of Medical Science, Vol 18, Iss 5, Pp 1231-1240 (2021)
Introduction Interferon (IFN)-β is known as an environmental trigger for the occurrence of autoimmune thyroid disease (AITD). However, the association of another type-1 IFN, IFN-β, with AITD is unknown. Material and methods In the study, we explor
Externí odkaz:
https://doaj.org/article/f3e36606d6734596b71c85aaa8c7be4e
Publikováno v:
Autoimmunity, Vol 53, Iss 5, Pp 261-269 (2020)
Cytokines and growth factors participate in immune responses, and the pathogenesis of autoimmune diseases. Herein, we simultaneously examined differential levels of 29 circulating factors to determine their associations in female patients with overt
Externí odkaz:
https://doaj.org/article/e3ec792e61734ed2bd810c090b08d5d5
Autor:
Szu-Yu Chen, Chi-Fu Chiang, Kou-Chou Chiu, Chao-Wen Cheng, Shih-Ming Huang, Pei-Hsuan Chen, Ching-Yang Chen, Yi-Shing Shieh
Publikováno v:
Journal of Dental Sciences, Vol 14, Iss 3, Pp 281-287 (2019)
Background/purpose: Macrophages participate in the periapical inflammation with pro-inflammatory M1 cells and anti-inflammatory M2 cells. Gas6/Axl signal is the responsible pathway for the activation of M1 and polarization of M2. The aim of this stud
Externí odkaz:
https://doaj.org/article/10930b7d5dfc4b9bb9e6cca80bc49754
Autor:
Wen-Yueh Hung, Jer-Hwa Chang, Yu Cheng, Chi-Kuan Chen, Ji-Qing Chen, Kuo-Tai Hua, Chao-Wen Cheng, Michael Hsiao, Chi-Li Chung, Wei-Jiunn Lee, Ming-Hsien Chien
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 1, Pp 337-355 (2018)
Background/Aims: Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) therapy is a clinical option for non-small cell lung cancer (NSCLC) harboring activating EGFR mutations or for cancer with wild-type (WT) EGFR when chemotherapy
Externí odkaz:
https://doaj.org/article/a43dcd58df144f428af979b5fe270d59
Autor:
Jer-Hwa Chang, Chao-Wen Cheng, Yi-Chieh Yang, Wan-Shen Chen, Wen-Yueh Hung, Jyh-Ming Chow, Pai-Sheng Chen, Michael Hsiao, Wei-Jiunn Lee, Ming-Hsien Chien
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-16 (2018)
Abstract Background Metastasis rather than the primary cancer determines the survival of cancer patients. Activation of Akt plays a critical role in the epithelial-to-mesenchymal transition (EMT), the initial step in lung cancer metastasis. Apigenin
Externí odkaz:
https://doaj.org/article/9b30ba857f0d4aaa94401846f26c4a42
Autor:
Chung-Ze Wu, Li-Chien Chang, Chao-Wen Cheng, Te-Chao Fang, Yuh-Feng Lin, Dee Pei, Jin-Shuen Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3407 (2021)
In recent decades, the obesity epidemic has resulted in morbidity and mortality rates increasing globally. In this study, using obese mouse models, we investigated the relationship among urokinase plasminogen activator (uPA), metabolic disorders, glo
Externí odkaz:
https://doaj.org/article/eb5c331b71ed4de9a434b60b16ac457c