Zobrazeno 1 - 10
of 378
pro vyhledávání: '"Chao-Jung Chen"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract 3’,5’-cyclic uridine monophosphate (cUMP) and 3’,5’-cyclic cytidine monophosphate (cCMP) have been established as bacterial second messengers in the phage defense system, named pyrimidine cyclase system for anti-phage resistance (Pyc
Externí odkaz:
https://doaj.org/article/aaceaf0014d244a6ac2e1fa5d9395cbf
Autor:
Chien-Hao Wang, Jai-Sing Yang, Chao-Jung Chen, San-Hua Su, Hsin-Yuan Yu, Yu-Ning Juan, Yu-Jen Chiu, Tsung-Jung Ho
Publikováno v:
Tzu-Chi Medical Journal, Vol 36, Iss 2, Pp 152-165 (2024)
Objectives: The protective effects and related mechanisms of Jing-Si herbal tea (JSHT) were investigated in cellular damage mediated by pro-inflammatory cytokines, including interleukin (IL)-1β, IL-6, and tumor necrosis factor-α, on normal human lu
Externí odkaz:
https://doaj.org/article/cff3f155fed94de58f112366226d4b5f
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Purine-containing nucleotide second messengers regulate diverse cellular activities. Cyclic di-pyrimidines mediate anti-phage functions in bacteria; however, the synthesis mechanism remains elusive. Here, we determine the high-resolution str
Externí odkaz:
https://doaj.org/article/8dca18426af4486fa80cab363a1ac94e
Autor:
Tzu-Ping Ko, Yu-Chuan Wang, Chia-Shin Yang, Mei-Hui Hou, Chao-Jung Chen, Yi-Fang Chiu, Yeh Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The bacterial Cyclic-oligonucleotide-Based Anti-phage Signaling System (CBASS) contains a CD-NTase that synthesizes cyclic di- and tri-nucleotides, and bacterial STING proteins recognize c-di-GMP generated by CD-NTase during phage infection and signa
Externí odkaz:
https://doaj.org/article/3bf6d388b3fb402f8510dc617dfce23a
Autor:
Mu-Lin Chiu, Jian-Shiun Chiou, Chao-Jung Chen, Wen-Miin Liang, Fuu-Jen Tsai, Yang-Chang Wu, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Chen-Hsing Chou, Cheng-Wen Lin, Te-Mao Li, Yu-Lung Hsu, Ying-Ju Lin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Hereditary Hemolytic Anemias (HHAs) are a rare but heterogeneous group of erythrocytic diseases, characterized by intrinsic cellular defects due to inherited genetic mutations. We investigated the efficacy of Chinese herbal medicine (CHM) in reducing
Externí odkaz:
https://doaj.org/article/516ba12faebe46feb2866a3237e9469a
Autor:
Hao-Teng Zheng, Zi-Xuan Zhuang, Chao-Jung Chen, Hsin-Yi Liao, Hung-Lin Chen, Huang-Chun Hsueh, Chih-Feng Chen, Shuen-Ei Chen, San-Yuan Huang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The adrenal gland responds to heat stress by epinephrine and glucocorticoid release to alleviate the adverse effects. This study investigated the effect of acute heat stress on the protein profile and histone modification in the adrenal glan
Externí odkaz:
https://doaj.org/article/7e1f28897ddf4ecab2c76ec7e1d24699
Autor:
Jiaxin Yu, Ni Tien, Yu-Ching Liu, Der-Yang Cho, Jia-Wen Chen, Yin-Tai Tsai, Yu-Chen Huang, Huei-Jen Chao, Chao-Jung Chen
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Rapidly identifying methicillin-resistant Staphylococcus aureus (MRSA) with high integration in the current workflow is critical in clinical practices. We proposed a matrix-assisted laser desorption/ionization-time-of-flight mass spectrometr
Externí odkaz:
https://doaj.org/article/8094490b8c52466682cd3eef88115d0c
Autor:
Hsin-Yao Wang, Chia-Ru Chung, Chao-Jung Chen, Ko-Pei Lu, Yi-Ju Tseng, Tzu-Hao Chang, Min-Hsien Wu, Wan-Ting Huang, Ting-Wei Lin, Tsui-Ping Liu, Tzong-Yi Lee, Jorng-Tzong Horng, Jang-Jih Lu
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/3ed27923887744babc175d8e50e8275b
Autor:
Fuu-Jen Tsai, Pei-Yuu Yang, Chao-Jung Chen, Ju-Pi Li, Te-Mao Li, Jian-Shiun Chiou, Chi-Fung Cheng, Po-Heng Chuang, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Bo Ban, Wen-Miin Liang, Ying-Ju Lin
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Liver cirrhosis is one of the main causes of the morbidity and mortality in liver diseases. Chinese herbal medicine (CHM) has long been used for the clinical treatment of liver diseases. This study was designed to explore the usag
Externí odkaz:
https://doaj.org/article/3d2019ee5a6d425a8c54f326eea03336
Autor:
Hsin-Yao Wang, Chia-Ru Chung, Chao-Jung Chen, Ko-Pei Lu, Yi-Ju Tseng, Tzu-Hao Chang, Min-Hsien Wu, Wan-Ting Huang, Ting-Wei Lin, Tsui-Ping Liu, Tzong-Yi Lee, Jorng-Tzong Horng, Jang-Jih Lu
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Enterococcus faecium is a clinically important pathogen that can cause significant morbidity and death. In this study, we aimed to develop a machine learning (ML) algorithm-based rapid susceptibility method to distinguish vancomycin-resistan
Externí odkaz:
https://doaj.org/article/ba1dfd8def6b4a558456b9b31a386683